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pro vyhledávání: '"Martin Kurtev"'
Publikováno v:
Journal of Biological Chemistry. 280:21313-21320
Members of the Sir2 family of NAD-dependent protein deacetylases regulate diverse cellular processes including aging, gene silencing, and cellular differentiation. Here, we report that the distant mammalian Sir2 homolog SIRT6 is a broadly expressed,
Autor:
Mark Leid, Rita Machado de Oliveira, Frederic Picard, Leonard Guarente, Thanaset Senawong, Martin Kurtev, Namjin Chung, Michael W. McBurney, Acharawan Topark-Ngarm
Publikováno v:
Nature. 429:771-776
Calorie restriction extends lifespan in organisms ranging from yeast to mammals. In yeast, the SIR2 gene mediates the life-extending effects of calorie restriction. Here we show that the mammalian SIR2 orthologue, Sirt1 (sirtuin 1), activates a criti
Autor:
Thanaset Senawong, Mark Leid, Michael W. McBurney, Acharawan Topark-Ngarm, Frédéric Picard, Leonard Guarente, Martin Kurtev, Namjin Chung, Rita Machado de Oliveira
Publikováno v:
Nature. 430:921-921
Nature 429, 771–776 (2004). It has been drawn to our attention by Vincent Keng that the image in the bottom-left frame of Fig. 1c of this Letter presents identical data to the one above it on the right. A mistake made by the authors during compilat