Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Martin Krkoška"'
Autor:
Jarmila Herůdková, Kamil Paruch, Prashant Khirsariya, Karel Souček, Martin Krkoška, Olga Vondálová Blanářová, Petr Sova, Alois Kozubík, Alena Hyršlová Vaculová
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 10, Pp 830-841 (2017)
Although Chk1 kinase inhibitors are currently under clinical investigation as effective cancer cell sensitizers to the cytotoxic effects of numerous chemotherapeutics, there is still a considerable uncertainty regarding their role in modulation of an
Externí odkaz:
https://doaj.org/article/e81b0f5a2c1d4cceb65c2243075f3a24
Autor:
Olga Vondálová Blanářová, Barbora Šafaříková, Jarmila Herůdková, Martin Krkoška, Silvie Tománková, Zuzana Kahounová, Ladislav Anděra, Jan Bouchal, Gvantsa Kharaishvili, Milan Král, Petr Sova, Alois Kozubík, Alena Hyršlová Vaculová
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188584 (2017)
Searching for new strategies for effective elimination of human prostate cancer cells, we investigated the cooperative cytotoxic action of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and two platinum-based complexes, cisplatin or
Externí odkaz:
https://doaj.org/article/f28d4460e94e49e89d81127c542aa443
Autor:
Ondřej Slabý, Kateřina Nevědělová, Igor Kiss, Veronika Zubáňová, Zdeněk Kala, Zuzana Tylichová, Jana Nekvindová, Jan Vondráček, Alena Hyršlová Vaculová, Lucia Bohovicova, Pavel Fabian, Martin Krkoška, Petr Kysela, Jarmila Herůdková, Lenka Ostřížková, Vladimir Palicka, Lenka Radová
Publikováno v:
Pharmacological Reports. 74:148-158
Background Hepatocellular carcinoma (HCC) is a major contributor to the worldwide cancer burden. Recent studies on HCC have demonstrated dramatic alterations in expression of several cytochrome P450 (CYP) family members that play a crucial role in bi
Autor:
Martin, Krkoška, Jana, Nekvindová, Kateřina, Nevědělová, Veronika, Zubáňová, Lenka, Radová, Jan, Vondráček, Jarmila, Herůdková, Ondřej, Slabý, Igor, Kiss, Lucia, Bohovicová, Pavel, Fabian, Zuzana, Tylichová, Zdeněk, Kala, Petr, Kysela, Lenka, Ostřížková, Vladimír, Palička, Alena, Hyršlová Vaculová
Publikováno v:
Pharmacological reports : PR. 74(1)
Hepatocellular carcinoma (HCC) is a major contributor to the worldwide cancer burden. Recent studies on HCC have demonstrated dramatic alterations in expression of several cytochrome P450 (CYP) family members that play a crucial role in biotransforma
Autor:
Helena Libalova, Lenka Šmerdová, Jana Svobodová, Alois Kozubík, Jiřina Procházková, Martin Krkoška, Markéta Kabátková, Miroslav Machala, Jiří Kléma, Jan Vondráček, Jan Topinka
Publikováno v:
Toxicological Sciences. 172:368-384
The aryl hydrocarbon receptor (AhR) activation has been shown to alter proliferation, apoptosis, or differentiation of adult rat liver progenitors. Here, we investigated the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated AhR activation
Autor:
Jan Vondráček, Alena Hyršlová Vaculová, Markéta Kabátková, Martin Krkoška, Jana Nekvindová, Ondřej Zapletal, Jana Svobodová
Publikováno v:
Toxicology. 461:152897
Cytochrome P450 family 1 (CYP1) enzymes contribute both to metabolism of xenobiotics and to the control of endogenous levels of ligands of the aryl hydrocarbon receptor (AhR). Their activities, similar to other CYPs, can be altered in tumor tissues.
Autor:
Ladislav Anděra, Alena Hyršlová Vaculová, Silvie Tománková, Jan Bouchal, Milan Král, Martin Krkoška, Petr Sova, Zuzana Kahounová, Barbora Šafaříková, Gvantsa Kharaishvili, Alois Kozubík, Olga Vondálová Blanářová, Jarmila Herůdková
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0188584 (2017)
PLoS ONE, Vol 12, Iss 11, p e0188584 (2017)
Searching for new strategies for effective elimination of human prostate cancer cells, we investigated the cooperative cytotoxic action of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and two platinum-based complexes, cisplatin or