Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Martin Kollmar"'
Autor:
Martin Kollmar, Tobias Welz, Aishwarya Ravi, Thomas Kaufmann, Noura Alzahofi, Klas Hatje, Asmahan Alghamdi, Jiyu Kim, Deborah A. Briggs, Annette Samol-Wolf, Olena Pylypenko, Alistair N. Hume, Pawel Burkhardt, Jan Faix, Eugen Kerkhoff
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-21 (2024)
Abstract An important question in cell biology is how cytoskeletal proteins evolved and drove the development of novel structures and functions. Here we address the origin of SPIRE actin nucleators. Mammalian SPIREs work with RAB GTPases, formin (FMN
Externí odkaz:
https://doaj.org/article/0ef371bb0f37464e940f4e2fa0201a73
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Heterologous protein expression is an important method for analysing cellular functions of proteins, in genetic circuit engineering and in overexpressing proteins for biopharmaceutical applications and structural biology research. The degene
Externí odkaz:
https://doaj.org/article/887d83c7ccac4a97b8b80af5ba2fb735
Autor:
Stefanie Mühlhausen, Hans Dieter Schmitt, Uwe Plessmann, Peter Mienkus, Pia Sternisek, Thorsten Perl, Michael Weig, Henning Urlaub, Oliver Bader, Martin Kollmar
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Yeasts of the CTG-clade lineage, which includes the human-infecting Candida albicans, Candida parapsilosis and Candida tropicalis species, are characterized by an altered genetic code. Instead of translating CUG codons as leucine,
Externí odkaz:
https://doaj.org/article/21810cf83f754ad98fa92e1970787823
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Coiled-coil regions were among the first protein motifs described structurally and theoretically. The simplicity of the motif promises that coiled-coil regions can be detected with reasonable accuracy and precision in any protein sequence. H
Externí odkaz:
https://doaj.org/article/457f24aabd3c4d23a4754297cf759afa
Autor:
Martin Kollmar, Stefanie Mühlhausen
Publikováno v:
BMC Evolutionary Biology, Vol 17, Iss 1, Pp 1-18 (2017)
Abstract Background The last eukaryotic common ancestor already had an amazingly complex cell possessing genomic and cellular features such as spliceosomal introns, mitochondria, cilia-dependent motility, and a cytoskeleton together with several intr
Externí odkaz:
https://doaj.org/article/b0897a9d84814666a4c1ac8fddbdb46f
Autor:
Dominic Simm, Martin Kollmar
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191924 (2018)
Stable single-alpha helices (SAH-domains) function as rigid connectors and constant force springs between structural domains, and can provide contact surfaces for protein-protein and protein-RNA interactions. SAH-domains mainly consist of charged ami
Externí odkaz:
https://doaj.org/article/ee2ac1629f864405800d38405dcf2267
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177716 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0174639.].
Externí odkaz:
https://doaj.org/article/adeabbcba9964b80ad623755b6e7175b
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174639 (2017)
Stable single-alpha helices (SAHs) are versatile structural elements in many prokaryotic and eukaryotic proteins acting as semi-flexible linkers and constant force springs. This way SAH-domains function as part of the lever of many different myosins.
Externí odkaz:
https://doaj.org/article/4f6310f7e05040dbbe34da4e032b2188
Autor:
Olena Pylypenko, Tobias Welz, Janine Tittel, Martin Kollmar, Florian Chardon, Gilles Malherbe, Sabine Weiss, Carina Ida Luise Michel, Annette Samol-Wolf, Andreas Till Grasskamp, Alistair Hume, Bruno Goud, Bruno Baron, Patrick England, Margaret A Titus, Petra Schwille, Thomas Weidemann, Anne Houdusse, Eugen Kerkhoff
Publikováno v:
eLife, Vol 5 (2016)
There is growing evidence for a coupling of actin assembly and myosin motor activity in cells. However, mechanisms for recruitment of actin nucleators and motors on specific membrane compartments remain unclear. Here we report how Spir actin nucleato
Externí odkaz:
https://doaj.org/article/c2c1af684db44be18ca98b689ff18474
Autor:
Martin Kollmar, Klas Hatje
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88111 (2014)
Multicellular animals possess two to three different types of muscle tissues. Striated muscles have considerable ultrastructural similarity and contain a core set of proteins including the muscle myosin heavy chain (Mhc) protein. The ATPase activity
Externí odkaz:
https://doaj.org/article/1e21dfb5f7284a389c5c383ea9d0744a