Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Martin Klingenberg"'
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 1355-1357 (2016)
The data reported herein are related to the article entitled: “The switching mechanism of the mitochondrial ADP/ATP carrier explored by free-energy landscapes” (Pietropaolo et al., 2016) [1].We report the coordinates of the ADP/ATP carrier (AAC2)
Externí odkaz:
https://doaj.org/article/ed4db41cc5364fc188d1164efd9fae8e
Autor:
Martin Klingenberg
Publikováno v:
Biochimie. 134:19-27
This review focuses on the biochemical work of UCP1 starting from the early observation by Ricquier and Kader in 1976. We entered this field in 1980 with the isolation of native UCP1 and then reported the amino acid sequence structure discovering a s
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1857:772-781
The ADP/ATP carrier (AAC) of mitochondria has been an early example for elucidating the transport mechanism alternating between the external (c-) and internal (m-) states (M. Klingenberg, Biochim. Biophys. Acta 1778 (2008) 1978-2021). An atomic resol
Autor:
Martin Klingenberg
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1788(10):2048-2058
Members of the mitochondrial carrier family interact with cardiolipin (CL) as evident from a variety of functional and structural effects. CL stabilises carrier proteins on isolation with detergents, with the Pi carrier as the prime example. CL is re
Autor:
Martin Klingenberg
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1778:1978-2021
Different from some more specialised short reviews, here a general although not encyclopaedic survey of the function, metabolic role, structure and mechanism of the ADP/ATP transport in mitochondria is presented. The obvious need for an “old fashio
Autor:
Shu-Gui Huang, Martin Klingenberg
Publikováno v:
European Journal of Biochemistry. 229:718-725
Binding of the fluorescent nucleotide derivative 2'-O-dansyl GTP and purine nucleotides to brown adipose tissue mitochondria from hamster was studied. 2'-O-Dansyl GTP binds with enhanced fluorescence to the uncoupling protein (UCP) in the mitochondri
Autor:
Martin Klingenberg
Publikováno v:
Biochimie. 89:1042-1048
Transport catalysis is analysed in terms of the "induced transition fit" (ITF) concept. The essentials of ITF are briefly elucidated, emphasizing the difference of substrate-protein interactions between enzymes and carriers exemplified by the paradig
Autor:
Martin Klingenberg
Publikováno v:
EMBO reports. 6:797-800
When the marvels of modern biological research are presented in the media, one image almost always appears: a person in a laboratory using a micropipette. This small but ubiquitous device has evolved into one of the icons of modern biotechnology, mol
Autor:
Martin Klingenberg
Publikováno v:
Archives of Biochemistry and Biophysics. 409:2-6
The total hemin content of washed rat liver microsomes is 2.15 times the cytochrome b5 content, only a small part being due to bound hemoglobin. The content of flavine is 4 5 that of cytochrome b5. The flavine probably does not contribute to the DPNH