Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Martin Klečka"'
Publikováno v:
European Journal of Organic Chemistry. 2015:7943-7961
A general access to 4-substituted 6-arylpyrrolo[2,3-d]pyrimidine (6-substituted 8-aryl-7-deazapurine derivatives) was developed based on iridium-catalyzed C–H borylations of pyrrolo[2,3-d]pyrimidines at the 6-position followed by the Suzuki cross-c
Autor:
Michal Hocek, Eva Tloušťová, Lenka Poštová Slavětínská, Petr Džubák, Martin Klečka, Marian Hajduch
Publikováno v:
MedChemComm. 6:576-580
A series of 7-phenylsulfanyl- or 7-(2-thienyl)sulfanyl-7-deazapurine bases bearing diverse substituents at position 6 was prepared through C–H sulfenylation of 6-chloro-7-deazapurine followed by cross-coupling or nucleophilic substitutions. The cor
Publikováno v:
European Journal of Organic Chemistry. 2014:7203-7210
A new chemoselective synthesis of pyrrolo[2,3-d]pyrimidines (7-deazapurines) bearing two different aryl groups at positions 4 and 5 was developed based on two orthogonal cross-couplings. Starting from 7-benzyl-protected 4-(phenylsulfanyl)-5-iodopyrro
Publikováno v:
RSC Adv.. 4:62140-62143
Protocols for selective Pd–Cu-catalyzed direct C–H amination or C–H chloroamination of 7-deazapurines with N-chloro-N-alkyl-arylsulfonamides have been developed leading either to 8-(arylsulfonyl)methylamino-7-deazapurines or to 7-chloro-8-(aryl
Publikováno v:
ChemInform. 46
Selective monoarylation at position 5 of substrate (I) becomes possible with Suzuki [-< conditions A)] or Stille coupling [-< conditions C), product (VIII)].
Publikováno v:
Collection of Czechoslovak Chemical Communications. 71:1221-1228
6-Allylpurine derivatives are formed by Cu(I)-catalyzed coupling of (9-benzyl-9H-purin-6-yl)- magnesium chloride with allyl halides. The reaction is accompanied by allylic rearrangement in some cases. Under acid conditions the double bond of the ally