Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Martin Kaliwoda"'
Autor:
W. Höllriegl, Jürgen Siekmann, P. Matthiessen, E.-M. Muchitsch, Katalin Varadi, Herbert Gritsch, Gerald Schrenk, Peter Turecek, Artur Mitterer, Friedrich Scheiflinger, A. Schiviz, Hartmut J. Ehrlich, Hans-Peter Prof. Schwarz, M. J. Bossard, M. Graninger, Martin Kaliwoda, M. Purtscher, T. Riley, Hanspeter Rottensteiner
Publikováno v:
Hämostaseologie. 32:S29-S38
SummaryA longer acting recombinant FVIII is expected to serve patients’ demand for a more convenient prophylactic therapy. We have developed BAX 855, a PEGylated form of Baxter’s rFVIII product ADVATE™ based on the ADVATE™ manufacturing proce
Autor:
Michael Graninger, Christian Konetschny, Meinhard Hasslacher, Martin Kaliwoda, Manfred Reiter, Artur Mitterer, Eva-Maria Muchitsch, Ernst Böhm, Michael Dockal, Friedrich Scheiflinger
Publikováno v:
BMC Proceedings, Vol 5, Iss Suppl 8, p P23 (2011)
BMC Proceedings
BMC Proceedings
IntroductionClearance mechanisms for rFVII (or the active enzymerFVIIa) and rFIX are influenced by post-translationalmodifications, especially N-glycosylation. This should beconsidered when choosing a recombinant expressionsystem in view of the varyi
Autor:
Alexandra Foettinger-Vacha, Martin Kaliwoda, Peter Matthiessen, Meinhard Hasslacher, Hanspeter Rottensteiner, Peter L Turecek, Artur Mitterer, Friedrich Scheiflinger
Publikováno v:
Blood. 120:2236-2236
Abstract 2236 Baxter has developed a human recombinant (r) ADAMTS13 for treatment of patients with hereditary TTP. The protein is produced in a CHO cell-line using serum and protein-free fermentation technology. The purification process does not use
Autor:
Friedrich Scheiflinger, Peter Matthiessen, Martin Kaliwoda, Meinhard Hasslacher, Alexandra Foettinger-Vacha, Peter Turecek, Artur Mitterer, Hanspeter Rottensteiner
Publikováno v:
Blood. 120:2235-2235
Abstract 2235 Baxter has developed a human recombinant (r) ADAMTS13 for treatment of patients with hereditary TTP. Here we characterize preclinical and clinical lots of rADAMTS13 with respect to their functional properties. The ability of rADAMTS13 t
Autor:
Artur Mitterer, Peter Matthiessen, Peter Turecek, Michael Graninger, Gerald Schrenk, Martin Kaliwoda, Friedrich Scheiflinger, Hartmut J. Ehrlich
Publikováno v:
Blood. 118:4356-4356
Abstract 4356 Baxter and Nektar have developed a longer acting recombinant FVIII (BAX 855), which is manufactured by coupling stable PEG using Nektar technology to Baxter’s full-length rFVIII bulk drug substance from the protein-free ADVATE™ manu
Autor:
Hanspeter Rottensteiner, Wolfgang Mundt, Friedrich Scheiflinger, Susanne Vejda, Martin Kaliwoda, Ernst Boehm, Manfred Reiter, Katalin Varadi, Hartmut J. Ehrlich, Peter Turecek
Publikováno v:
Blood. 116:4658-4658
Abstract 4658 Human coagulation factor IX (FIX) is a vitamin-K-dependent coagulation factor whose absence or dysfunction causes hemophilia B. Treatment of hemophilia B is based on replacement therapy using highly purified FIX concentrates. Baxter has