Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Martin Kaczocha"'
Autor:
Sherrye T. Glaser, Kalani Jayanetti, Saida Oubraim, Andrew Hillowe, Elena Frank, Jason Jong, Liqun Wang, Hehe Wang, Iwao Ojima, Samir Haj-Dahmane, Martin Kaczocha
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Fatty acid binding proteins (FABPs) govern intracellular lipid transport to cytosolic organelles and nuclear receptors. More recently, FABP5 has emerged as a key regulator of synaptic endocannabinoid signaling, suggesting that FABPs may broa
Externí odkaz:
https://doaj.org/article/051e942f5eec42278754deaffb2bf38b
Autor:
Jasper Murphy, Sery Pak, Lana Shteynman, Ian Winkeler, Zhaosheng Jin, Martin Kaczocha, Sergio D. Bergese
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4722 (2024)
Chronic postsurgical pain (CPSP) following total knee arthroplasty (TKA) and total hip arthroplasty (THA) is a prevalent complication of joint replacement surgery which has the potential to decrease patient satisfaction, increase financial burden, an
Externí odkaz:
https://doaj.org/article/85a521dcb25b47afa070b6b7edf7b63c
Autor:
Saida Oubraim, Ruixiang Wang, Kathryn Hausknecht, Martin Kaczocha, Roh-Yu Shen, Samir Haj-Dahmane
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Mood disorders, including anxiety and depression caused by prenatal ethanol exposure (PE) are prevalent conditions in fetal alcohol spectrum disorders (FASDs). Prenatal ethanol exposure is associated with persistent dysfunctions of several n
Externí odkaz:
https://doaj.org/article/c26d064334a9484bb011af6fcda1e12e
Autor:
Diane M. Bogdan, Keith Studholme, Adriana DiBua, Chris Gordon, Martha P. Kanjiya, Mei Yu, Michelino Puopolo, Martin Kaczocha
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The endocannabinoid anandamide (AEA) produces antinociceptive effects by activating cannabinoid receptor 1 (CB1). However, AEA also serves as an agonist at transient receptor potential vanilloid receptor 1 (TRPV1) in nociceptive sensory neur
Externí odkaz:
https://doaj.org/article/c1cb01ae7c1e46c1ab55a8d0f95094d3
Autor:
Andrew Hillowe, Chris Gordon, Liqun Wang, Robert C Rizzo, Lloyd C Trotman, Iwao Ojima, Agnieszka Bialkowska, Martin Kaczocha
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292483 (2023)
Prostate cancer is a leading cause of cancer-related deaths in men in the United States. Although treatable when detected early, prostate cancer commonly transitions to an aggressive castration-resistant metastatic state. While taxane chemotherapeuti
Externí odkaz:
https://doaj.org/article/620d251e83954e02a10d8f068f447ba8
Autor:
Mohammad Fauzan, Saida Oubraim, Mei Yu, Sherrye T. Glaser, Martin Kaczocha, Samir Haj-Dahmane
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The endocannabinoid (eCB) anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are endogenous lipid neurotransmitters that regulate an array of physiological functions, including pain, stress homeostasis, and reward. Fatty acid-binding protein 5 (FABP5
Externí odkaz:
https://doaj.org/article/c2a6642812754ab3bd18d02f3f673122
Autor:
David E Komatsu, Sardar M Z Uddin, Chris Gordon, Martha P Kanjiya, Diane Bogdan, Justice Achonu, Adriana DiBua, Hira Iftikhar, Amanda Ackermann, Rohan J Shah, Jason Shieh, Agnieszka B Bialkowska, Martin Kaczocha
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278632 (2022)
Total knee arthroplasty (TKA) is the final treatment option for patients with advanced knee osteoarthritis (OA). Unfortunately, TKA surgery is accompanied by acute postoperative pain that is more severe than arthroplasty performed in other joints. El
Externí odkaz:
https://doaj.org/article/50003744588645228d7d4ddd61bbf0de
Autor:
Martin Kaczocha, Syed Azim, James Nicholson, Mario J. Rebecchi, Yong Lu, Tian Feng, Jamie L. Romeiser, Ruth Reinsel, Sabeen Rizwan, Shivam Shodhan, Nora D. Volkow, Helene Benveniste
Publikováno v:
BMC Anesthesiology, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background The primary goal of this study was to determine whether administration of intrathecal morphine reduces postoperative pain. The secondary goal was to determine the effect of intrathecal morphine upon circulating levels of the weakl
Externí odkaz:
https://doaj.org/article/c9680f89f73f42d3801817d5bf0c3af8
Publikováno v:
Immunity & Ageing, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background We have previously reported elevated expression of multiple pro-inflammatory markers in the lumbar spinal cord (LSC) of middle-aged male rats compared to young adults suggesting a para-inflammatory state develops in the LSC by mid
Externí odkaz:
https://doaj.org/article/4146de167bb044369d8c004cb3a80dad
Autor:
Jinwoo Kim, Diane M Bogdan, Matthew W Elmes, Monaf Awwa, Su Yan, Joyce Che, Garam Lee, Dale G Deutsch, Robert C Rizzo, Martin Kaczocha, Iwao Ojima
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218619 (2019)
(-)-Incarvillateine (INCA) is a natural product that has garnered attention due to its purported analgesic effects and historical use as a pain reliever in China. α-Truxillic acid monoesters (TAMEs) constitute a class of inhibitors targeting fatty a
Externí odkaz:
https://doaj.org/article/22652621445e47aaae6cb8fa64861e67