Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Martin K Church"'
Autor:
Martin K Church, Diana S Church
Publikováno v:
Indian Journal of Dermatology, Vol 58, Iss 3, Pp 219-224 (2013)
H 1- antihistamines, the mainstay of treatment for urticaria, were developed from anticholinergic drugs more than 70 years ago. They act as inverse agonists rather than antagonists of histamine H 1 -receptors which are members of the G-protein family
Externí odkaz:
https://doaj.org/article/b4fc608ddce8481d9eccefc5b2292a77
Publikováno v:
World Allergy Organization Journal, Vol 4, Iss , Pp S22-S27 (2011)
This article reviews the molecular biology of the interaction of histamine with its H1-receptor and describes the concept that H1-antihistamines are not receptor antagonists but are inverse agonists i.e. they produce the opposite effect on the recept
Externí odkaz:
https://doaj.org/article/1dc6b8525fec4e32930b04880e49f687
Autor:
Karsten Weller, Claudia Ziege, Petra Staubach, Knut Brockow, Frank Siebenhaar, Karoline Krause, Sabine Altrichter, Martin K Church, Marcus Maurer
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e23931 (2011)
BACKGROUND: The guidelines recommend that first line treatment of chronic spontaneous urticaria should be second generation non-sedating H(1)-antihistamines with a positive recommendation against the use of old sedating first generation antihistamine
Externí odkaz:
https://doaj.org/article/40bd39f6887b473888386f4926cd3d13
Autor:
Emek Kocatürk, Indrashis Podder, Ana C. Zenclussen, Alicja Kasperska Zajac, Daniel Elieh-Ali-Komi, Martin K. Church, Marcus Maurer
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
Chronic urticaria (CU) is a mast cell-driven chronic inflammatory disease with a female predominance. Since CU affects mostly females in reproductive age, pregnancy is an important aspect to consider in the context of this disease. Sex hormones affec
Externí odkaz:
https://doaj.org/article/ff6b1eea6c504a5d88f00f39b1cfe861
Autor:
Kanokvalai Kulthanan, Martin K. Church, Eva Maria Grekowitz, Tomasz Hawro, Lea Alice Kiefer, Kanyalak Munprom, Yanisorn Nanchaipruek, Chuda Rujitharanawong, Dorothea Terhorst-Molawi, Marcus Maurer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundChronic inducible urticaria (CIndU) constitutes a group of nine different CIndUs in which pruritic wheals and/or angioedema occur after exposure to specific and definite triggers. Histamine released from activated and degranulating skin mas
Externí odkaz:
https://doaj.org/article/88bd2df797eb4f53bb5b7110e4ed14f7
Autor:
Jörg Scheffel, Niklas A. Mahnke, Zonne L. M. Hofman, Steven de Maat, Jim Wu, Hanna Bonnekoh, Reuben J. Pengelly, Sarah Ennis, John W. Holloway, Marieluise Kirchner, Philipp Mertins, Martin K. Church, Marcus Maurer, Coen Maas, Karoline Krause
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Systemic autoinflammatory syndromes such as cryopyrin-associated periodic syndrome (CAPS) are rare and often involve genes related to the inflammasome. Here, the authors report a syndrome characterised by systemic inflammation and cold-induced urtica
Externí odkaz:
https://doaj.org/article/e98d9cd321e045eeb259cd21cfaa4555
Autor:
Katrine Y. Baumann, Martin K. Church, Geraldine F. Clough, Sven Roy Quist, Martin Schmelz, Per Stahl Skov, Chris D. Anderson, Line Kring Tannert, Ana Maria Giménez-Arnau, Stefan Frischbutter, Jörg Scheffel, Marcus Maurer
Publikováno v:
Clinical and Translational Allergy, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Skin microdialysis (SMD) is a versatile sampling technique that can be used to recover soluble endogenous and exogenous molecules from the extracellular compartment of human skin. Due to its minimally invasive character, SMD can be applied i
Externí odkaz:
https://doaj.org/article/8d4b63443dd5427ebd22d605235a334b
Publikováno v:
Journal of Dermatological Science. 103:10-15
Cholinergic urticaria (CholU) is characterized by the occurrence of itchy wheals induced by sweating. Intradermal injections of acetylcholine (ACh) have been proposed to help with diagnosing CholU and subgrouping of patients, but controlled studies a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab009885186f0cdb15974104f160928
https://doi.org/10.1016/j.jdermsci.2021.05.001
https://doi.org/10.1016/j.jdermsci.2021.05.001
Autor:
Marcus Maurer, Z. Vadasz, L. Matanes, Elias Toubi, Jacob Bejar, H. Sheffer, A. Barzilai, D. A. Sabag, Martin K. Church
Publikováno v:
Clinical & Experimental Allergy. 50:799-804
Background Chronic spontaneous urticaria (CSU) is considered an autoimmune disorder in 50% of cases at least, in which T- and mast cell mediators are considered to be the primary cause of symptoms. However, H1 -antihistamines, cyclosporine A, and oma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a50fb11276de197cb83554da127594
https://doi.org/10.1111/cea.13616
https://doi.org/10.1111/cea.13616
Autor:
Sabine Altrichter, Marcus Maurer, Pavel Kolkhir, Qingqing Jiao, Martin Metz, Per Stahl Skov, Martin K. Church, Stefan Frischbutter, Jie Shen Fok
Publikováno v:
Altrichter, S, Frischbutter, S, Fok, J S, Kolkhir, P, Jiao, Q, Skov, P S, Metz, M, Church, M K & Maurer, M 2020, ' The role of eosinophils in chronic spontaneous urticaria ', Journal of Allergy and Clinical Immunology, vol. 145, no. 6, pp. 1510-1516 . https://doi.org/10.1016/j.jaci.2020.03.005
Chronic spontaneous urticaria (CSU) is considered to be primarily a mast cell–driven disease. However, recent evidence suggests that eosinophils may also have an axial role in symptomology. Histologic studies have demonstrated the presence of both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defa9830420cd5b9a76a7eba20004e2c
https://doi.org/10.1016/j.jaci.2020.03.005
https://doi.org/10.1016/j.jaci.2020.03.005