Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Martin Jutras"'
Autor:
Jessica Hindi, Marc‐Olivier Pilon, Maxime Meloche, Grégoire Leclair, Essaïd Oussaïd, Isabelle St‐Jean, Martin Jutras, Marie‐Josée Gaulin, Ian Mongrain, David Busseuil, Jean Lucien Rouleau, Jean‐Claude Tardif, Marie‐Pierre Dubé, Simon deDenus
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 5, Pp 872-885 (2023)
Abstract Females present a higher risk of adverse drug reactions. Sex‐related differences in drug concentrations may contribute to these observations but they remain understudied given the underrepresentation of females in clinical trials. The aim
Externí odkaz:
https://doaj.org/article/58f822ad9b2840d0901676770757397e
Autor:
Sabrina Robert, Marc‐Olivier Pilon, Essaïd Oussaïd, Maxime Meloche, Grégoire Leclair, Martin Jutras, Marie‐Josée Gaulin, Ian Mongrain, David Busseuil, Jean‐Claude Tardif, Marie‐Pierre Dubé, Simon deDenus
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract Small studies suggest that amiodarone is a weak inhibitor of cytochrome P450 (CYP) 2D6. Inhibition of CYP2D6 leads to increases in concentrations of drugs metabolized by the enzyme, such as metoprolol. Considering that both metoprolol and am
Externí odkaz:
https://doaj.org/article/0853f8a5071a463ca8c6f9d55b6c7249
Autor:
Marc‐Olivier Pilon, Grégoire Leclair, Essaïd Oussaïd, Isabelle St‐Jean, Martin Jutras, Marie‐Josée Gaulin, Ian Mongrain, David Busseuil, Jean Lucien Rouleau, Jean‐Claude Tardif, Marie‐Pierre Dubé, Simon deDenus
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 8, Pp 2024-2034 (2022)
Abstract ABCG2 is a gene that codes for the human breast cancer resistance protein (BCRP). It is established that rs2231142 G>T, a single nucleotide polymorphism of the ABCG2 gene, is associated with gout and poor response to allopurinol, a uric acid
Externí odkaz:
https://doaj.org/article/f9425dbf0f014bcc896fcaa842b04bf7
Autor:
Maxime Meloche, Grégoire Leclair, Martin Jutras, Essaïd Oussaïd, Marie‐Josée Gaulin, Ian Mongrain, David Busseuil, Jean‐Claude Tardif, Marie‐Pierre Dubé, Simon deDenus
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 4, Pp 1063-1073 (2022)
Abstract Large, observational genetic studies are commonly used to identify genetic factors associated with diseases and disease‐related traits. Such cohorts have not been commonly used to identify genetic predictors of drug dosing or concentration
Externí odkaz:
https://doaj.org/article/81b54697e31d490090a5d831aea25000
Autor:
Ina Puscas, Florian Bernard-Patrzynski, Martin Jutras, Marc-André Lécuyer, Lyne Bourbonnière, Alexandre Prat, Grégoire Leclair, V. Gaëlle Roullin
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 514 (2020)
The authors wish to make the following corrections to this paper [...]
Externí odkaz:
https://doaj.org/article/e4ef6982589246e3ab81bd9c222f500c
Autor:
Ina Puscas, Florian Bernard-Patrzynski, Martin Jutras, Marc-André Lécuyer, Lyne Bourbonnière, Alexandre Prat, Grégoire Leclair, V. Gaëlle Roullin
Publikováno v:
Pharmaceutics, Vol 11, Iss 11, p 587 (2019)
Since most preclinical drug permeability assays across the blood-brain barrier (BBB) are still evaluated in rodents, we compared an in vitro mouse primary endothelial cell model to the mouse b.End3 and the acellular parallel artificial membrane perme
Externí odkaz:
https://doaj.org/article/381b5d7e6cfc40b9bc35b7cf59ec2eaf
Autor:
Anaëlle Monfort, Caroline Morin, Martin Jutras, Stéphane Charest, Grégoire Leclair, Ema Ferreira
Publikováno v:
Breastfeeding Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53ca2ecc1a2afb06f66f8d8438c78bae
https://doi.org/10.1089/bfm.2023.0042
https://doi.org/10.1089/bfm.2023.0042
Autor:
Isabelle St-Jean, Marie-Pierre Dubé, Javed Butler, Michael M. Givertz, Yassamin Feroz Zada, João Pedro Ferreira, Essaïd Oussaïd, Andreas P. Kalogeropoulos, Grégoire Leclair, Robert J. Mentz, Martin Jutras, W.H. Wilson Tang, Simon de Denus, Jean L. Rouleau
Publikováno v:
Eur J Heart Fail
AIMS In Aldosterone Targeted Neurohormonal Combined with Natriuresis Therapy in Heart Failure (ATHENA-HF), high-dose spironolactone (100 mg daily) did not improve efficacy endpoints over usual care [placebo or continued low-dose spironolactone (25 mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5b776b8b69599162ef5c4d8d8d4fe2
https://doi.org/10.1002/ejhf.1802
https://doi.org/10.1002/ejhf.1802
Autor:
Sylvie Poirier Larabie, Martin Jutras, Grégoire Leclair, Isabelle St-Jean, Christine Kleinert, François Gagné, Christian Gagnon
Publikováno v:
Environmental science and pollution research international. 29(30)
Aquatic organisms are continuously exposed to emerging contaminants coming from urban effluents of wastewater treatment plants. The contamination of surface water by those effluents poses a number of environmental risks, and pharmaceuticals are part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c28323e0c8d0261957a5d98727acef
https://pubmed.ncbi.nlm.nih.gov/35146607
https://pubmed.ncbi.nlm.nih.gov/35146607
Autor:
Ema Ferreira, Brigitte Martin, Grégoire Leclair, Anaëlle Monfort, Martin Jutras, Isabelle Boucoiran
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 204
A bioanalytical method by high performance liquid chromatography coupled to mass spectrometry (HPLC-MS/MS) for the simultaneous quantification of 17 drugs and 2 major active metabolites in breast milk was developed and validated. Breast milk samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f54ab19b291db952d6a676c73a69f42
https://pubmed.ncbi.nlm.nih.gov/34273657
https://pubmed.ncbi.nlm.nih.gov/34273657