Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Martin Jakab"'
Autor:
Christian Mayr, Tobias Kiesslich, Dino Bekric, Marlena Beyreis, Michael Kittl, Celina Ablinger, Elen Neureiter, Martin Pichler, Felix Prinz, Markus Ritter, Daniel Neureiter, Martin Jakab, Heidemarie Dobias
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287769 (2023)
Biliary tract cancer is a deadly disease with limited therapeutic options. Ouabain is a well-known inhibitor of the pumping function of Na+/K+-ATPase, though there is evidence that low concentrations of ouabain lead to a reduction of cell viability o
Externí odkaz:
https://doaj.org/article/ee71fae858cb43a488c0159eb41426f2
Autor:
Michael Kittl, Martina Winklmayr, Julia Preishuber-Pflügl, Victoria Strobl, Martin Gaisberger, Markus Ritter, Martin Jakab
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
In a variety of physiological and pathophysiological conditions, cells are exposed to acidic environments. Severe synovial fluid acidification also occurs in a progressive state of osteoarthritis (OA) affecting articular chondrocytes. In prior studie
Externí odkaz:
https://doaj.org/article/93a404db289148d5aedd6c5240597ae3
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 5, Pp 951-969 (2019)
Externí odkaz:
https://doaj.org/article/3615fb9108294da0b1aea0a66089c100
Autor:
Christian Mayr, Marlena Beyreis, Heidemarie Dobias, Martin Gaisberger, Julia Fuchs, Martin Pichler, Markus Ritter, Martin Jakab, Katharina Helm, Daniel Neureiter, Tobias Kiesslich
Publikováno v:
Cell Adhesion & Migration, Vol 13, Iss 1, Pp 76-82 (2019)
Cellular migration is essential in diverse physiological and pathophysiological processes. Here, we present a protocol for quantitative analysis of migration using confluence detection allowing continuous, non-endpoint measurement with minimal hands-
Externí odkaz:
https://doaj.org/article/b9adb13df766495f940ed2d8fd1e2dd0
Autor:
Michael Kittl, Martina Winklmayr, Katharina Helm, Johannes Lettner, Martin Gaisberger, Markus Ritter, Martin Jakab
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Chondrocytes face extreme alterations of extracellular osmolarity and pH, which force them to appropriately regulate their cell volume (CV) and cellular pH. Perturbations of these mechanisms lead to chondrocyte death and ultimately to osteoarthritis
Externí odkaz:
https://doaj.org/article/25647c51ab3f41e2b83f4a67c265b878
Autor:
Michael Kittl, Heidemarie Dobias, Marlena Beyreis, Tobias Kiesslich, Christian Mayr, Martin Gaisberger, Markus Ritter, Hubert H. Kerschbaum, Martin Jakab
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 4, Pp 1460-1473 (2018)
Background/Aims: The neutral, non-essential amino acid glycine has manifold functions and effects under physiological and pathophysiological conditions. Besides its function as a neurotransmitter in the central nervous system, glycine also exerts imm
Externí odkaz:
https://doaj.org/article/3f68b6d4a51b41f3ad84825f5d1d85bc
Autor:
Martin Jakab, Nina Ketterl, Johannes Fürst, Marlena Beyreis, Michael Kittl, Tobias Kiesslich, Cornelia Hauser-Kronberger, Martin Gaisberger, Markus Ritter
Publikováno v:
Cellular Physiology and Biochemistry, Vol 43, Iss 3, Pp 1037-1051 (2017)
Background/Aims: Glucose-stimulated insulin secretion (GSIS) of pancreatic β-cells involves glucose uptake and metabolism, closure of KATP channels and depolarization of the cell membrane potential (Vmem), activation of voltage-activated Ca2+ curren
Externí odkaz:
https://doaj.org/article/9d08d18e6ed64e019e6e97f02b32088a
Autor:
Katharina Helm, Marlena Beyreis, Christian Mayr, Markus Ritter, Martin Jakab, Tobias Kiesslich, Kristjan Plaetzer
Publikováno v:
Cellular Physiology and Biochemistry, Vol 41, Iss 3, Pp 1011-1019 (2017)
Background/Aims: For in vitro cytotoxicity testing, discrimination of apoptosis and necrosis represents valuable information. Viability analysis performed at two different time points post treatment could serve such a purpose because the dynamics of
Externí odkaz:
https://doaj.org/article/c8465c34db334f90925959e119e7df27
Autor:
Michael Kittl, Marlena Beyreis, Munkhtuya Tumurkhuu, Johannes Fürst, Katharina Helm, Anna Pitschmann, Martin Gaisberger, Sabine Glasl, Markus Ritter, Martin Jakab
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 1, Pp 278-293 (2016)
Background/Aims: Previously we described insulinotropic effects of Leonurus sibiricus L. plant extracts used for diabetes mellitus treatment in Traditional Mongolian Medicine. The flavonoid quercetin and its glycoside rutin, which exert anti-diabetic
Externí odkaz:
https://doaj.org/article/42269a80f3bc4a0abaa79d38dcad5401
Autor:
Martin Jakab, Sabine Hofer, Andrea Ravasio, Felix Huber, Sabine Schmidt, Wolfgang Hitzl, John P. Geibel, Johannes Fürst, Markus Ritter
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 5, Pp 1507-1526 (2014)
Background/Aims: The ATP12A gene codes for a non-gastric H+/K+ ATPase, which is expressed in a wide variety of tissues. The aim of this study was to test for the molecular and functional expression of the non-gastric H+/K+ ATPase ATP12A/ATP1AL1 in un
Externí odkaz:
https://doaj.org/article/1f5dfa41fbe7442982b074fd0a9afe32