Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Martin Jacko"'
Autor:
Yocelyn Recinos, Dmytro Ustianenko, Yow-Tyng Yeh, Xiaojian Wang, Martin Jacko, Lekha V. Yesantharao, Qiyang Wu, Chaolin Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Pre-mRNA splicing, a key process in gene expression, can be therapeutically modulated using various drug modalities, including antisense oligonucleotides (ASOs). However, determining promising targets is hampered by the challenge of systemat
Externí odkaz:
https://doaj.org/article/50eafa1abd784c8ab1e55ddaab52c2b2
Autor:
Kelvin F Cho, Shawn M Gillespie, Nicholas A Kalogriopoulos, Michael A Quezada, Martin Jacko, Michelle Monje, Alice Y Ting
Publikováno v:
eLife, Vol 11 (2022)
Technologies for detecting cell-cell contacts are powerful tools for studying a wide range of biological processes, from neuronal signaling to cancer-immune interactions within the tumor microenvironment. Here, we report TRACC (Transcriptional Readou
Externí odkaz:
https://doaj.org/article/ba21240dbd5f4fa98d5721e296c4f39a
Autor:
Sebastien M. Weyn-Vanhentenryck, Huijuan Feng, Dmytro Ustianenko, Rachel Duffié, Qinghong Yan, Martin Jacko, Jose C. Martinez, Marianne Goodwin, Xuegong Zhang, Ulrich Hengst, Stavros Lomvardas, Maurice S. Swanson, Chaolin Zhang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The precise timing of neurodevelopmental splicing switches and the underlying regulatory mechanisms remain poorly understood. This study identifies two major waves of developmental switches under the control of distinct combinations of RNA-binding pr
Externí odkaz:
https://doaj.org/article/e95f34f767ed420686c114eb449248ee
Autor:
Kelvin F Cho, Shawn M Gillespie, Nicholas A Kalogriopoulos, Michael A Quezada, Martin Jacko, Michelle Monje, Alice Y Ting
Publikováno v:
eLife. 11
Technologies for detecting cell-cell contacts are powerful tools for studying a wide range of biological processes, from neuronal signaling to cancer-immune interactions within the tumor microenvironment. Here, we report TRACC (Transcriptional Readou
Autor:
Dmytro Ustianenko, Stavros Lomvardas, Martin Jacko, Ulrich Hengst, Xuegong Zhang, Sebastien M. Weyn-Vanhentenryck, Chaolin Zhang, Maurice S. Swanson, Qinghong Yan, Huijuan Feng, Jose C. Martinez, Rachel Duffié, Marianne Goodwin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications
Alternative splicing (AS) is one crucial step of gene expression that must be tightly regulated during neurodevelopment. However, the precise timing of developmental splicing switches and the underlying regulatory mechanisms are poorly understood. He
Autor:
Sebastien M. Weyn-Vanhentenryck, Chaolin Zhang, Martin Jacko, Huijuan Feng, Joy Pai, Ke Xu, Damian J. Williams, John W. Smerdon, Rui Yan, Hynek Wichterle
Publikováno v:
Neuron. 97:853-868.e6
Summary Neuronal maturation requires dramatic morphological and functional changes, but the molecular mechanisms governing this process are not well understood. Here, we studied the role of Rbfox1, Rbfox2, and Rbfox3 proteins, a family of tissue-spec
Publikováno v:
Biomolecular Nmr Assignments
ZCCHC9 is a human nuclear protein with sequence homology to yeast Air1p/Air2p proteins which are RNA-binding subunits of the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex involved in nuclear RNA quality control and degradation in yeast. The ZCCHC9 p