Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Martin Jaburek"'
Autor:
Martin Jabůrek, Eduardo Klöppel, Pavla Průchová, Oleksandra Mozheitova, Jan Tauber, Hana Engstová, Petr Ježek
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103283- (2024)
We asked whether acute redox signaling from mitochondria exists concomitantly to fatty acid- (FA-) stimulated insulin secretion (FASIS) at low glucose by pancreatic β-cells. We show that FA β-oxidation produces superoxide/H2O2, providing: i) mitoch
Externí odkaz:
https://doaj.org/article/2c62519b300e44dfa58a44a1a60d3131
Autor:
Ason C. Y. Chiang, Jan Ježek, Peiqiang Mu, Ying Di, Anna Klucnika, Martin Jabůrek, Petr Ježek, Hansong Ma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Genetic screens have been used extensively to probe interactions between nuclear genes and their impact on phenotypes. Probing interactions between mitochondrial genes and their phenotypic outcome, however, has not been possible due to a lac
Externí odkaz:
https://doaj.org/article/535c6d0b32ad4ccfa77fbdd9ef88c699
Autor:
Pavla Průchová, Klára Gotvaldová, Katarína Smolková, Lukáš Alán, Blanka Holendová, Jan Tauber, Alexander Galkin, Petr Ježek, Martin Jabůrek
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 198 (2022)
Mitochondrial Ca2+-independent phospholipase A2γ (iPLA2γ/PNPLA8) was previously shown to be directly activated by H2O2 and release free fatty acids (FAs) for FA-dependent H+ transport mediated by the adenine nucleotide translocase (ANT) or uncoupli
Externí odkaz:
https://doaj.org/article/53699d1eb9834f9982df0e27cebb3b65
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 678 (2021)
Patatin-like phospholipase domain-containing protein PNPLA8, also termed Ca2+-independent phospholipase A2γ (iPLA2γ), is addressed to the mitochondrial matrix (or peroxisomes), where it may manifest its unique activity to cleave phospholipid side-c
Externí odkaz:
https://doaj.org/article/25e4aeb6e464408b86fecf9c1be4edbd
Autor:
Petr Ježek, Blanka Holendová, Martin Jabůrek, Jan Tauber, Andrea Dlasková, Lydie Plecitá-Hlavatá
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 197 (2021)
Pancreatic β-cell insulin secretion, which responds to various secretagogues and hormonal regulations, is reviewed here, emphasizing the fundamental redox signaling by NADPH oxidase 4- (NOX4-) mediated H2O2 production for glucose-stimulated insulin
Externí odkaz:
https://doaj.org/article/a4811a875d4446ca9f8d9188dbc70cbf
Autor:
Elena A Malingriaux, Anne Rupprecht, Lars Gille, Olga Jovanovic, Petr Jezek, Martin Jaburek, Elena E Pohl
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77786 (2013)
The production of reactive oxygen species (ROS) in mitochondria is very sensitive to the proton motive force and may be decreased by mild uncoupling, mediated e.g. by mitochondrial uncoupling proteins (UCPs). UCPs were conversely hypothesized to be a
Externí odkaz:
https://doaj.org/article/73c5601a52bc489dafef0f5e07e71a33
Publikováno v:
Free Radical Biology and Medicine. 192:81-82
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::537cf0ffd9dcdb554e8b8fe049a8e9d4
https://doi.org/10.1016/j.freeradbiomed.2022.10.140
https://doi.org/10.1016/j.freeradbiomed.2022.10.140
Publikováno v:
Free Radical Biology and Medicine. 192:82-83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5decde45372709832c18d4331ba33a5a
https://doi.org/10.1016/j.freeradbiomed.2022.10.142
https://doi.org/10.1016/j.freeradbiomed.2022.10.142
Publikováno v:
Free Radical Biology and Medicine. 192:91
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::473271234a02b963d5334c79616720fb
https://doi.org/10.1016/j.freeradbiomed.2022.10.160
https://doi.org/10.1016/j.freeradbiomed.2022.10.160
Publikováno v:
Free Radical Biology and Medicine. 145:S87-S88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa3688a24da0e66c7a975c24d0956fa9
https://doi.org/10.1016/j.freeradbiomed.2019.10.233
https://doi.org/10.1016/j.freeradbiomed.2019.10.233