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of 7
pro vyhledávání: '"Martin J. Wilby"'
Autor:
Martin J. Wilby, Carolyn Hopkins, Emma Bedson, Sue Howlin, Girvan Burnside, Elizabeth J. Conroy, Dyfrig A. Hughes, Manohar Sharma, Anthony Marson, Simon R. Clark, Paula Williamson
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-7 (2018)
Abstract Background Sciatica is a common condition reported to affect over 3% of the UK population at any time and is often caused by a prolapsed intervertebral disc (PID). Although the duration and severity of symptoms can vary, pain persisting beyo
Externí odkaz:
https://doaj.org/article/a0418d3c3c464c1e9a107cfa377d0f3a
Autor:
Martin J Wilby, Ashley Best, Eifiona Wood, Girvan Burnside, Emma Bedson, Hannah Short, Dianne Wheatley, Daniel Hill-McManus, Manohar Sharma, Simon Clark, Jennifer Bostock, Sally Hay, Ganesan Baranidharan, Cathy Price, Richard Mannion, Peter J Hutchinson, Dyfrig A Hughes, Anthony Marson, Paula R Williamson
Publikováno v:
Health Technology Assessment, Vol 25, Iss 24 (2021)
Background: Sciatica is a common condition reported to affect > 3% of the UK population at any time and is most often caused by a prolapsed intervertebral disc. Currently, there is no uniformly adopted treatment strategy. Invasive treatments, such as
Externí odkaz:
https://doaj.org/article/822c34010724485e9bf788140139f60f
Publikováno v:
Experimental Neurology. 159:225-236
We have treated spinal cord injured rats with demyelination plus Schwann cell transplantation and assessed neurite outgrowth in a quantifiable model of axonal regeneration. Axonal injuries of differing severity were induced in the dorsal funiculus of
Publikováno v:
The Journal of emergency medicine. 42(2)
Background: Spontaneous spinal epidural hematoma (SSEH) is a rare cause of spinal cord compression that requires emergency investigation and treatment. Prompt diagnosis is essential to prevent morbidity and mortality. Objectives: Our goal was to repo
Autor:
Juin Fok-Seang, Barbara J. Gour, James W. Fawcett, Martin J. Wilby, Orest W. Blaschuk, Elizabeth M. Muir
Publikováno v:
Molecular and cellular neurosciences. 14(1)
Astrocytes exclude Schwann cells (SCs) from the central nervous system (CNS) at peripheral nerve entry zones and restrict their migration after transplantation into the CNS. We have modeled the interactions between SCs, astrocytes, and fibroblasts in
Autor:
Kathryn H. Adcock, John H. Rogers, Elizabeth M. Muir, Simon R. Sinclair, James W. Fawcett, Martin J. Wilby, Stephen B. Dunnett, Rike Zietlow, Philippe Horellou
We have developed a novel Schwann cell line, SCTM41, derived from postnatal sciatic nerve cultures and have stably transfected a clone with a rat glial cell line-derived neurotrophic factor (GDNF) construct. Coculture with this GDNF-secreting clone e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e27fae94a0fc0cf6d6578b42f85137
https://europepmc.org/articles/PMC6782537/
https://europepmc.org/articles/PMC6782537/
Autor:
Stephen L. Nishimura, Charles H. Streuli, Gwynneth M. Edwards, James W. Fawcett, Kevin Boylen, Martin J. Wilby, Richard Milner, Robert Pytela, Charles ffrench-Constant
Publikováno v:
Developmental Biology. (2):215-228
Myelination of the peripheral nervous system (PNS) requires the migration of Schwann cells during both development and regeneration. We have characterized the expression pattern of Schwann cell integrins and analyzed their role in migration on differ