Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Martin J. Serra"'
Autor:
Claire V. Crowther, Laura E. Jones, Eric M. Mastrogiacomo, Claire A. Porterfield, Martin J. Serra, Jessica N. Morelli, Jessica L. Kent
Publikováno v:
RNA. 23:217-228
Fifty-three RNA duplexes containing two single nucleotide bulge loops were optically melted in 1 M NaCl in order to determine the thermodynamic parameters ΔH°, ΔS°, ΔG°37, and TM for each duplex. Because of the large number of possible combinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86ebfdf56ea759099ad530a44f7544b
https://doi.org/10.1261/rna.056168.116
https://doi.org/10.1261/rna.056168.116
Publikováno v:
RNA. 21:975-984
Eleven RNA hairpins containing 2-aminopurine (2-AP) in either base-paired or single nucleotide bulge loop positions were optically melted in 1 M NaCl; and, the thermodynamic parameters ΔH°, ΔS°, ΔG°37, and TM for each hairpin were determined. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aafc45493113a1235f05745fbf75ef7
https://doi.org/10.1261/rna.048306.114
https://doi.org/10.1261/rna.048306.114
Autor:
Lesley R. Sevcik, Audra L. Sinclair, Martin J. Serra, Alice A. Deckert, Elizabeth L. McMichael, Kara Ostrosky, Elisabeth E. Whitman, Brittany Rauzan, Rachel Cave, Rachel Stegemann
Publikováno v:
Biochemistry. 52:765-772
The rates of duplex formation for two octamers of DNA (5' d-CACGGCTC/5' d-GAGCCGTG and 5' d-CACAGCAC/5' d-GTGCTGTG), the homologous RNA, and both sets of hybrids in 1 M NaCl buffer have been measured using stopped-flow spectroscopy. In addition, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c75a611d5f2fc42a6028a3682fb70ab
https://doi.org/10.1021/bi3013005
https://doi.org/10.1021/bi3013005
Autor:
Julie Estes, Gregory D. Frattini, Michael D. McCann, Martin J. Serra, Kelly A. Klapec, Geoffery F.S. Lim, Michelle L. Manni, Robert J. Knarr, Jessica L. Gratton
Publikováno v:
RNA. 17:108-119
Thirty-one RNA duplexes containing single-nucleotide bulge loops were optically melted in 1 M NaCl, and the thermodynamic parameters ΔH°, ΔS°, ΔG°37, and TM for each sequence were determined. The bulge loops were of the group II variety, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f437577cfcb3faa9943f032c2ef90b3
https://doi.org/10.1261/rna.2306911
https://doi.org/10.1261/rna.2306911
Autor:
Susan M. Freier, Martin J. Serra, Scott Davis, Christine Esau, Stephanie Propp, Eric E. Swayze, Balkrishen Bhat, Garth A. Kinberger, C. Frank Bennett, Laura E. Jones
Publikováno v:
Nucleic Acids Research
Chemically modified antisense oligonucleotides (ASOs) are widely used as a tool to functionalize microRNAs (miRNAs). Reduction of miRNA level after ASO inhibition is commonly reported to show efficacy. Whether this is the most relevant endpoint for m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c9201374cb3f1fcc4ae3d2fd9aa685
https://doi.org/10.1093/nar/gkn904
https://doi.org/10.1093/nar/gkn904
Autor:
Yukiko Stranger-Jones, Chad A. Griffith, Joshua M. Blose, Jason D. Long, Kelly A. Klapec, Vasiliy Sim, Allison C. Zyra, Martin J. Serra, Michelle L. Manni
Publikováno v:
Biochemistry. 46:15123-15135
Fifty-nine RNA duplexes containing single-nucleotide bulge loops were optically melted in 1 M NaCl, and the thermodynamic parameters DeltaH degrees, DeltaS degrees, DeltaG 37 degrees, and TM for each sequence were determined. Sequences from this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1918263f7e5dcdd0d436e72c07f2171
https://doi.org/10.1021/bi700736f
https://doi.org/10.1021/bi700736f
Publikováno v:
Nucleic Acids Research
Thermodynamic parameters are reported for duplex formation of 48 self-complementary RNA duplexes containing Watson-Crick terminal base pairs (GC, AU and UA) with all 16 possible 3' double-nucleotide overhangs; mimicking the structures of short interf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2822fde6e8d88ce0f3f32cc80e6519fa
http://europepmc.org/articles/PMC1500867
http://europepmc.org/articles/PMC1500867
Publikováno v:
RNA. 11:512-516
Thermodynamic parameters are reported for duplex formation in 1 M NaCl for 16 RNA sequences, each containing a core tetramer duplex, GGCC, and a 3′ overhang consisting of two bases. The results indicate additional double-helical stability is confer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c47964921c03272cd92faf6d16dbb9f
https://doi.org/10.1261/rna.7254905
https://doi.org/10.1261/rna.7254905
Publikováno v:
Biochemistry. 43:11813-11817
Thermodynamic parameters are reported for hairpin formation in 1 M NaCl by RNA sequence of the type GCAXUAAUYUGC, where XY is the set of 10 possible mismatch base pairs. A nearest-neighbor analysis of the data indicates that the free energy of loop f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699951861d63aeb55a6c8d78030a15e9
https://doi.org/10.1021/bi049954i
https://doi.org/10.1021/bi049954i
Autor:
Jessica L. Kent, Martin J. Serra, Michael D. McCann, Geoffrey F.S. Lim, Brandon L. Panaro, Daniel Phillips
Publikováno v:
RNA (New York, N.Y.). 20(6)
Thirty-five RNA duplexes containing single nucleotide bulge loops were optically melted and the thermodynamic parameters for each duplex determined. The bulge loops were of the group III variety, where the bulged nucleotide is either a AG/U or CU/G,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e644d42b5d913d0b958ddc8c3386279e
https://pubmed.ncbi.nlm.nih.gov/24742935
https://pubmed.ncbi.nlm.nih.gov/24742935