Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Martin J. Llewelyn"'
Autor:
Angela McBride, Nguyen Lam Vuong, Nguyen Van Hao, Nguyen Quang Huy, Ho Quang Chanh, Nguyen Thi Xuan Chau, Nguyen Minh Nguyet, Damien K. Ming, Nguyen Thanh Ngoc, Phung Tran Huy Nhat, Nguyen Thanh Phong, Luong Thi Hue Tai, Phan Vinh Tho, Dinh The Trung, Dong Thi Hoai Tam, Huynh Trung Trieu, Ronald Bertus Geskus, Martin J. Llewelyn, C. Louise Thwaites, Sophie Yacoub
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Dengue is a neglected tropical disease, for which no therapeutic agents have shown clinical efficacy to date. Clinical trials have used strikingly variable clinical endpoints, which hampers reproducibility and comparability of fin
Externí odkaz:
https://doaj.org/article/7ff61bf43c8845dea91bf39ed5bbf930
Autor:
Josef Prazak, Irina Irincheeva, Martin J. Llewelyn, Daiana Stolz, Luis García de Guadiana Romualdo, Rolf Graf, Theresia Reding, Holger J. Klein, Philippe Eggimann, Yok-Ai Que
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-10 (2021)
Abstract Background Accurate biomarkers to diagnose infection are lacking. Studies reported good performance of pancreatic stone protein (PSP) to detect infection. The objective of the study was to determine the performance of PSP in diagnosing infec
Externí odkaz:
https://doaj.org/article/3a44793dc4784e9db676e6f9d0b74c17
Autor:
Trinh Manh Hung, Nguyen Van Hao, Lam Minh Yen, Angela McBride, Vu Quoc Dat, H. Rogier van Doorn, Huynh Thi Loan, Nguyen Thanh Phong, Martin J. Llewelyn, Behzad Nadjm, Sophie Yacoub, C. Louise Thwaites, Sayem Ahmed, Nguyen Van Vinh Chau, Hugo C. Turner, The Vietnam ICU Translational Applications Laboratory (VITAL) Investigators, Dang Phuong Thao, Dang Trung Kien, Doan Bui Xuan Thy, Dong Huu Khanh Trinh, Du Hong Duc, Ronald Geskus, Ho Bich Hai, Ho Quang Chanh, Ho Van Hien, Huynh Trung Trieu, Evelyne Kestelyn, Le Dinh Van Khoa, Le Thanh Phuong, Luu Hoai Bao Tran, Luu Phuoc An, Angela Mcbride, Nguyen Lam Vuong, Nguyen Quang Huy, Nguyen Than Ha Quyen, Nguyen Thanh Ngoc, Nguyen Thi Giang, Nguyen Thi Le Thanh, Nguyen Thi Phuong Dung, Nguyen Thi Phuong Thao, Ninh Thi Thanh Van, Phan Nguyen Quoc Khanh, Phung Khanh Lam, Phung Tran Huy Nhat, Guy Thwaites, Tran Minh Duc, Jennifer Ilo Van Nuil, Vu Ngo Thanh Huyen, Cao Thi Tam, Duong Bich Thuy, Ha Thi Hai Duong, Ho Dang Trung Nghia, Le Buu Chau, Le Mau Toan, Le Ngoc Minh Thu, Le Thi Mai Thao, Luong Thi Hue Tai, Nguyen Hoan Phu, Nguyen Quoc Viet, Nguyen Thanh Nguyen, Nguyen Thi Kim Anh, Nguyen Van Thanh Duoc, Pham Kieu Nguyet Oanh, Phan Thi Hong Van, Phan Tu Qui, Phan Vinh Tho, Truong Thi Phuong Thao, Natasha Ali, David Clifton, Mike English, Shadi Ghiasi, Heloise Greeff, Jannis Hagenah, Ping Lu, Jacob McKnight, Chris Paton, Pantelis Georgiou, Bernard Hernandez Perez, Kerri Hill-Cawthorne, Alison Holmes, Stefan Karolcik, Damien Ming, Nicolas Moser, Liane Canas, Alberto Gomez, Hamideh Kerdegari, Marc Modat, Reza Razavi, Linda Denehy, Luigi Pisani, Marcus Schultz
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
BackgroundCritically ill patients often require complex clinical care by highly trained staff within a specialized intensive care unit (ICU) with advanced equipment. There are currently limited data on the costs of critical care in low-and middle-inc
Externí odkaz:
https://doaj.org/article/f7077071376a4b659d7c43626ab987a1
Autor:
Laurence S. J. Roope, James Buchanan, Liz Morrell, Koen B. Pouwels, Katy Sivyer, Fiona Mowbray, Lucy Abel, Elizabeth L. A. Cross, Lucy Yardley, Tim Peto, A. Sarah Walker, Martin J. Llewelyn, Sarah Wordsworth
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background Deciding whether to discontinue antibiotics at early review is a cornerstone of hospital antimicrobial stewardship practice worldwide. In England, this approach is described in government guidance (‘Start Smart then Focus’). H
Externí odkaz:
https://doaj.org/article/04ca5440f28f4bb39b4c50d3dfc7dba6
Autor:
Fiona Mowbray, Katy Sivyer, Marta Santillo, Nicola Jones, Tim E. A. Peto, A. Sarah Walker, Martin J. Llewelyn, Lucy Yardley
Publikováno v:
Pilot and Feasibility Studies, Vol 6, Iss 1, Pp 1-12 (2020)
Abstract Background We aimed to investigate and optimise the acceptability and usefulness of a patient leaflet about antibiotic prescribing decisions made during hospitalisation, and to explore individual patient experiences and preferences regarding
Externí odkaz:
https://doaj.org/article/7b77fcf1697b4104a0230fdc970d8b67
Autor:
William L. Hamilton, Sacha-Marie Pires, Samantha Lippett, Vikesh Gudka, Elizabeth L. A. Cross, Martin J. Llewelyn
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-7 (2020)
Abstract Background Minimising antimicrobial overuse is needed to limit antimicrobial resistance. There is little evidence on how often microbiological testing informs antimicrobial de-escalation (e.g. stopping, shortening duration, switching to narr
Externí odkaz:
https://doaj.org/article/ba7981f826174cb79ce2042223837634
Autor:
Gwenan M. Knight, Nicholas G. Davies, Caroline Colijn, Francesc Coll, Tjibbe Donker, Danna R. Gifford, Rebecca E. Glover, Mark Jit, Elizabeth Klemm, Sonja Lehtinen, Jodi A. Lindsay, Marc Lipsitch, Martin J. Llewelyn, Ana L. P. Mateus, Julie V. Robotham, Mike Sharland, Dov Stekel, Laith Yakob, Katherine E. Atkins
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Antibiotics remain the cornerstone of modern medicine. Yet there exists an inherent dilemma in their use: we are able to prevent harm by administering antibiotic treatment as necessary to both humans and animals, but we must be mi
Externí odkaz:
https://doaj.org/article/d28eeb4aec5a465e8f6ad8ee4343de81
Autor:
Natasha V.D.V. Ratnaraja, Angharad P. Davies, Bridget L. Atkins, Rishi Dhillon, Nikunj Mahida, Samuel Moses, Joanne Herman, Anna Checkley, David Partridge, Martin J. Llewelyn
Publikováno v:
Clinical Infection in Practice, Vol 12, Iss , Pp 100095- (2021)
Infection expertise in the NHS has historically been provided predominantly by hospital-based medical microbiologists responsible for provision of diagnostic services and advice to front-line clinicians. While most hospitals had consultant-led microb
Externí odkaz:
https://doaj.org/article/a0c14db97e504dc3b64e51cc0c8c69e7
Autor:
Joanne Euden, Philip Pallmann, Detelina Grozeva, Mahableshwar Albur, Stuart E. Bond, Lucy Brookes-Howell, Paul Dark, Thomas Hellyer, Susan Hopkins, Philip Howard, Martin J. Llewelyn, Wakunyambo Maboshe, Iain J. McCullagh, Margaret Ogden, Helena Parsons, David Partridge, Neil Powell, Dominick Shaw, Bethany Shinkins, Tamas Szakmany, Stacy Todd, Emma Thomas-Jones, Robert M. West, Enitan D. Carrol, Jonathan A. T. Sandoe
Publikováno v:
Methods and Protocols, Vol 5, Iss 6, p 95 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel virus responsible for the coronavirus disease 2019 (COVID-19) pandemic. Although COVID-19 is a viral illness, many patients admitted to hospital are prescribed antibiotics, based
Externí odkaz:
https://doaj.org/article/0b3bc8a1efbc464eb86f02a8e4f4abfa
Autor:
Ann Sarah Walker, Eric Budgell, Magda Laskawiec-Szkonter, Katy Sivyer, Sarah Wordsworth, Jack Quaddy, Marta Santillo, Adele Krusche, Laurence S. J. Roope, Nicole Bright, Fiona Mowbray, Nicola Jones, Kieran Hand, Najib Rahman, Melissa Dobson, Emma Hedley, Derrick Crook, Mike Sharland, Chris Roseveare, F. D. Richard Hobbs, Chris Butler, Louella Vaughan, Susan Hopkins, Lucy Yardley, Timothy E. A. Peto, Martin J. Llewelyn, on behalf of the ARK trial team
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background To ensure patients continue to get early access to antibiotics at admission, while also safely reducing antibiotic use in hospitals, one needs to target the continued need for antibiotics as more diagnostic information becomes ava
Externí odkaz:
https://doaj.org/article/0690f54a01af48e9bf221bd91444969c