Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Martin J. Firth"'
Autor:
Ursula R. Kees, Jette Ford, Amy L. Samuels, Denise Anderson, Martin J. Firth, Alex H. Beesley
Patients relapsing with T-cell acute lymphoblastic leukemia (T-ALL) face a dismal outcome. The aim of this study was to identify new markers of drug resistance and clinical response in T-ALL. We measured gene expression and drug sensitivity in 15 ped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a377a32eda6df9a0ded304a0b16393
https://doi.org/10.1158/0008-5472.c.6505596
https://doi.org/10.1158/0008-5472.c.6505596
Autor:
Peter Herrmann, Siavash Ahmadi-Noorbakhsh, Adrian Regli, Gabrielle C. Musk, David Joseph Reese, J. Jane Pillow, Martin J. Firth
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-14 (2021)
Intensive Care Medicine Experimental
Intensive Care Medicine Experimental
Background Intra-abdominal hypertension (IAH) is common in critically ill patients and is associated with increased morbidity and mortality. High positive end-expiratory pressures (PEEP) can reverse lung volume and oxygenation decline caused by IAH,
Autor:
Michaela Fakiola, Anshuman Mishra, Madhukar Rai, Shri Prakash Singh, Rebecca A O'Leary, Stephen Ball, Richard W Francis, Martin J Firth, Ben T Radford, E Nancy Miller, Shyam Sundar, Jenefer M Blackwell
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15807 (2010)
Genome wide linkage studies (GWLS) have provided evidence for loci controlling visceral leishmaniasis on Chromosomes 1p22, 6q27, 22q12 in Sudan and 6q27, 9p21, 17q11-q21 in Brazil. Genome wide studies from the major focus of disease in India have not
Externí odkaz:
https://doaj.org/article/39ddd52d3bcf49b383192be1f1eea845
Publikováno v:
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics. 158(3)
Introduction A growing number of adult patients are seeking orthodontic treatment. This research aimed to analyze the particulars of patients seeking retreatment and identify the causes of their original treatment failure. Methods An online questionn
Publikováno v:
Tropical Medicine and Infectious Disease; Volume 1; Issue 1; Pages: 3
As the number of Australians engaging in short-term international travel increases, so does the opportunity for importing overseas-acquired infectious diseases. This study aimed to determine knowledge of infectious disease risks and pre-travel health
Autor:
Fiona Marriage, Lisa W Martin, Fiona M. Wood, Daniel J. Haustead, Phillip E. Melton, Katharine F. Adcroft, Andrew W. Stevenson, Philip J. R. Day, Martin J. Firth, Suzanne Rea, Mark W. Fear, Vishal Saxena, Robyn Silla
Publikováno v:
Scientific Reports
Haustead, D J, Stevenson, A, Saxena, V, Marriage, F, Firth, M, Silla, R, Martin, L W, Adcroft, K F, Rea, S M, Day, P, Melton, P, Wood, F M & Fear, M W 2016, ' Transcriptome analysis of human ageing in male skin shows mid-life period of variability and central role of NF-κB ', Scientific Reports, vol. 6, 26846 . https://doi.org/10.1038/srep26846
Haustead, D J, Stevenson, A, Saxena, V, Marriage, F, Firth, M, Silla, R, Martin, L W, Adcroft, K F, Rea, S M, Day, P, Melton, P, Wood, F M & Fear, M W 2016, ' Transcriptome analysis of human ageing in male skin shows mid-life period of variability and central role of NF-κB ', Scientific Reports, vol. 6, 26846 . https://doi.org/10.1038/srep26846
Age is well-known to be a significant factor in both disease pathology and response to treatment, yet the molecular changes that occur with age in humans remain ill-defined. Here, using transcriptome profiling of healthy human male skin, we demonstra
Autor:
J. Ford, Ursula R. Kees, Joseph R Freitas, Alex H. Beesley, Martin J. Firth, Renae E. Weller, Kanchana U. Perera
Publikováno v:
British Journal of Cancer
Glucocorticoids (GCs) are among the most important drugs for acute lymphoblastic leukaemia (ALL), yet despite their clinical importance, the exact mechanisms involved in GC cytotoxicity and the development of resistance remain uncertain. We examined
Autor:
Ursula R. Kees, David L. Baker, Katrin Hoffmann, Jette Ford, Saranga Senanayake, Martin J. Firth, Nicholas de Klerk, Joseph R Freitas, Alex H. Beesley
Publikováno v:
British Journal of Haematology. 140:656-664
Despite high cure rates 25% of children with acute lymphoblastic leukaemia (ALL) relapse and have dismal outcome. Crucially, many are currently stratified as standard risk (SR) and additional markers to improve patient stratification are required. He
Autor:
Martin J. Firth, David R. Brigstock, Joanne M. Boag, Joseph R Freitas, Jette Ford, Ursula R. Kees, Nicholas de Klerk, Alex H. Beesley
Publikováno v:
British Journal of Haematology. 138:740-748
Summary In recent years microarrays have been used extensively to characterize gene expression in acute lymphoblastic leukaemia (ALL). Few studies, however, have analysed normal haematopoietic cell populations to identify altered gene expression in A
Autor:
Joseph R Freitas, Nicolas H de Klerk, David L. Baker, Kanchana U. Perera, Alex H. Beesley, Nicholas G. Gottardo, Ursula R. Kees, Martin J. Firth, Katrin Hoffmann
Publikováno v:
British Journal of Haematology. 137:319-328
In the last four decades the survival of patients with newly diagnosed childhood T-cell acute lymphoblastic leukaemia (T-ALL) has improved dramatically. In sharp contrast, relapsed T-ALL continues to confer a dismal prognosis. We sought to determine