Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Martin J. D'Souza"'
Autor:
Dedeepya Pasupuleti, Priyal Bagwe, Amarae Ferguson, Mohammad N. Uddin, Martin J. D’Souza, Susu M. Zughaier
Publikováno v:
Vaccines, Vol 12, Iss 9, p 1049 (2024)
Inducing T lymphocyte (T-cell) activation and proliferation with specificity against a pathogen is crucial in vaccine formulation. Assessing vaccine candidates’ ability to induce T-cell proliferation helps optimize formulation for its safety, immun
Externí odkaz:
https://doaj.org/article/3b27ddeff29a4fdcb2c9b80a1c7a0363
Autor:
Sarthak Shah, Parth Patel, Priyal Bagwe, Akanksha Kale, Amarae Ferguson, Emmanuel Adediran, Tanisha Arte, Revanth Singh, Mohammad N. Uddin, Martin J. D’Souza
Publikováno v:
Viruses, Vol 16, Iss 6, p 865 (2024)
Humans continue to be at risk from the Zika virus. Although there have been significant research advancements regarding Zika, the absence of a vaccine or approved treatment poses further challenges for healthcare providers. In this study, we develope
Externí odkaz:
https://doaj.org/article/eb5dbadd31a54fe39c9fd9502cdd3425
Autor:
Smital Patil, Sharon Vijayanand, Ipshita Menon, Keegan Braz Gomes, Akanksha Kale, Priyal Bagwe, Shadi Yacoub, Mohammad N. Uddin, Martin J. D’Souza
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1131 (2023)
COVID-19 continues to cause an increase in the number of cases and deaths worldwide. Due to the ever-mutating nature of the virus, frequent vaccination against COVID-19 is anticipated. Most of the approved SARS-CoV-2 vaccines are administered using t
Externí odkaz:
https://doaj.org/article/ada22f0c60f64b41b81e32c8d3cabc87
Autor:
Sharon Vijayanand, Smital Patil, Ipshita Menon, Keegan Braz Gomes, Akanksha Kale, Priyal Bagwe, Mohammad N. Uddin, Susu M. Zughaier, Martin J. D’Souza
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 895 (2023)
SARS-CoV-2, the causal agent of COVID-19, is a contagious respiratory virus that frequently mutates, giving rise to variant strains and leading to reduced vaccine efficacy against the variants. Frequent vaccination against the emerging variants may b
Externí odkaz:
https://doaj.org/article/5b0c959d05dd4fea8c733bd6934e3bb4
Autor:
Akanksha Kale, Devyani Joshi, Ipshita Menon, Priyal Bagwe, Smital Patil, Sharon Vijayanand, Keegan Braz Gomes, Mohammad N. Uddin, Martin J. D’Souza
Publikováno v:
Vaccines, Vol 11, Iss 3, p 583 (2023)
Although the global Zika epidemic in 2015–16 fueled vaccine development efforts, there is no approved Zika vaccine or treatment available to date. Current vaccine platforms in clinical trials are administered via either subcutaneous or intramuscula
Externí odkaz:
https://doaj.org/article/0e4cf3946da64c5fa287089e80078778
Publikováno v:
Vaccines, Vol 11, Iss 3, p 543 (2023)
Tumor cells express antigens that should induce immune-mediated rejection; however, spontaneous rejection of established tumors is rare. Recent evidence suggests that patients suffering from cancer exhibit an elevation in regulatory T cells populatio
Externí odkaz:
https://doaj.org/article/a6aabce0859840e096e09055dadc7a3b
Autor:
Trinh Phuong Vo, Gitika Panicker, Kimberly Braz-Gomes, Ashwin C. Parenky, Ira Rajbhandari, Mangalathu S. Rajeevan, Elizabeth R. Unger, Martin J. D’Souza, Mohammad N. Uddin
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1128 (2022)
Human papillomavirus (HPV) causes cervical cancer among women and is associated with other anogenital cancers in men and women. Prophylactic particulate vaccines that are affordable, self-administered and efficacious could improve uptake of HPV vacci
Externí odkaz:
https://doaj.org/article/2fd700d7a8424506a5b29e1c09bdb451
Autor:
Sharon Vijayanand, Smital Patil, Devyani Joshi, Ipshita Menon, Keegan Braz Gomes, Akanksha Kale, Priyal Bagwe, Shadi Yacoub, Mohammad N. Uddin, Martin J. D’Souza
Publikováno v:
Vaccines, Vol 10, Iss 9, p 1491 (2022)
This ‘proof-of-concept’ study aimed to test the microparticulate vaccine delivery system and a transdermal vaccine administration strategy using dissolving microneedles (MN). For this purpose, we formulated poly(lactic-co-glycolic) acid (PLGA) mi
Externí odkaz:
https://doaj.org/article/187ad2b23ac447419adcffc646b43182
Autor:
Keegan Braz Gomes, Ipshita Menon, Priyal Bagwe, Lotika Bajaj, Sang-Moo Kang, Martin J. D’Souza
Publikováno v:
Viruses, Vol 14, Iss 9, p 1920 (2022)
In this study, we demonstrate how encapsulating a conserved influenza ectodomain matrix-2 protein virus-like particle (M2e5x VLP) into a pre-crosslinked bovine serum albumin (BSA) polymeric matrix enhances in vitro antigen immunogenicity and in vivo
Externí odkaz:
https://doaj.org/article/cdf2d1dd1d1f415ea187d600f2288a28
Publikováno v:
Vaccines, Vol 10, Iss 7, p 983 (2022)
The emergence of drug-resistant gonorrhea infections worldwide combined with the lack of a vaccine is alarming. We prepared a novel microparticulate (MP) vaccine formulation using whole-cell inactivated Neisseria gonorrhoeae as the vaccine antigen, w
Externí odkaz:
https://doaj.org/article/a06f7f927d4b42f4b2caf975a3a0814f