Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Martin J Kelly"'
Autor:
Jian Qiu, Heidi M Rivera, Martha A Bosch, Stephanie L Padilla, Todd L Stincic, Richard D Palmiter, Martin J Kelly, Oline K Rønnekleiv
Publikováno v:
eLife, Vol 7 (2018)
The neuropeptides tachykinin2 (Tac2) and kisspeptin (Kiss1) in hypothalamic arcuate nucleus Kiss1 (Kiss1ARH) neurons are essential for pulsatile release of GnRH and reproduction. Since 17β-estradiol (E2) decreases Kiss1 and Tac2 mRNA expression in K
Externí odkaz:
https://doaj.org/article/8c43e44e4ebd4186b9a91911319ae1ba
Autor:
Jian Qiu, Casey C Nestor, Chunguang Zhang, Stephanie L Padilla, Richard D Palmiter, Martin J Kelly, Oline K Rønnekleiv
Publikováno v:
eLife, Vol 5 (2016)
Kisspeptin (Kiss1) and neurokinin B (NKB) neurocircuits are essential for pubertal development and fertility. Kisspeptin neurons in the hypothalamic arcuate nucleus (Kiss1ARH) co-express Kiss1, NKB, dynorphin and glutamate and are postulated to provi
Externí odkaz:
https://doaj.org/article/aaa722b0f09c4914835ef0f2f9847498
Autor:
Ana B Ropero, Paloma Alonso-Magdalena, Sergi Soriano, Pablo Juan-Picó, Troy A Roepke, Martin J Kelly, Ángel Nadal
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34650 (2012)
The non-steroidal compound STX modulates the hypothalamic control of core body temperature and energy homeostasis. The aim of this work was to study the potential effects of STX on pancreatic β-cell function. 1-10 nM STX produced an increase in gluc
Externí odkaz:
https://doaj.org/article/654f20452c13425aa16520891ffdafc2
Autor:
Diane Lebesgue, Michael Traub, Maxine De Butte-Smith, Christopher Chen, R Suzanne Zukin, Martin J Kelly, Anne M Etgen
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8642 (2010)
Pretreatment with 17beta-estradiol (E2) is profoundly neuroprotective in young animals subjected to focal and global ischemia. However, whether E2 retains its neuroprotective efficacy in aging animals, especially when administered after brain insult,
Externí odkaz:
https://doaj.org/article/30cf4247503e4abfa98385e530d46cac
Autor:
Jian Qiu, Martha A. Bosch, Todd L. Stincic, Avery C. Hunker, Larry S. Zweifel, Oline K. Rønnekleiv, Martin J. Kelly
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101645- (2022)
Objective: Proopiomelanocortin (POMC) neurons are the key anorexigenic hypothalamic neuron for integrating metabolic cues to generate the appropriate output for maintaining energy homeostasis and express the requisite channels as a perfect synaptic i
Externí odkaz:
https://doaj.org/article/6c8f4be480964addb3b17dc712cb716d
Autor:
Joseph F. Quinn, Martin J. Kelly, Christopher J. Harris, Wyatt Hack, Nora E. Gray, Veronika Kulik, Zoe Bostick, Barbara H. Brumbach, Philip F. Copenhaver
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105888- (2022)
Based on previous evidence that the non-steroidal estrogen receptor modulator STX mitigates the effects of neurotoxic Amyloid-β (Aβ) in vitro, we have evaluated its neuroprotective benefits in a mouse model of Alzheimer's disease. Cohorts of 5XFAD
Externí odkaz:
https://doaj.org/article/782f7a69b4644a658b5e92462ffc06b9
Autor:
Todd L. Stincic, Martha A. Bosch, Avery C. Hunker, Barbara Juarez, Ashley M. Connors, Larry S. Zweifel, Oline K. Rønnekleiv, Martin J. Kelly
Publikováno v:
Molecular Metabolism, Vol 49, Iss , Pp 101218- (2021)
Objective: Arcuate nucleus neuropeptide Y/agouti-related peptide (NPY/AgRP) neurons drive ingestive behavior. The M-current, a subthreshold non-inactivating potassium current, plays a critical role in regulating NPY/AgRP neuronal excitability. Fastin
Externí odkaz:
https://doaj.org/article/fb095b3020044ae88ead4c1b4cac825f
Autor:
Jian Qiu, Martin J. Kelly, Ashley M. Connors, Stefanie Kaech Petrie, Todd L. Stincic, Oline K. Rønnekleiv, Martha A. Bosch
Publikováno v:
The Journal of Neuroscience. 41:9688-9701
Kisspeptin (Kiss1) neurons are essential for reproduction, but their role in the control of energy balance and other homeostatic functions remains unclear. High-frequency firing of hypothalamic arcuate Kiss1 (Kiss1ARH) neurons releases kisspeptin int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d23591cfc18004e6f01d22e55e03543
https://doi.org/10.1523/jneurosci.0622-21.2021
https://doi.org/10.1523/jneurosci.0622-21.2021
Autor:
Todd L. Stincic, Martin J. Kelly
Publikováno v:
J Neuroendocrinol
Pregnancy is energetically demanding and, therefore, by necessity reproduction and energy balance are inextricably linked. With insufficient or excessive energy stores a female is liable to suffer complications during pregnancy or produce unhealthy o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474a1f4b033d7cc19f41332ba8a26672
https://europepmc.org/articles/PMC10228899/
https://europepmc.org/articles/PMC10228899/
