Zobrazeno 1 - 10
of 538
pro vyhledávání: '"Martin J Kelly"'
Autor:
Jian Qiu, Martha A. Bosch, Todd L. Stincic, Avery C. Hunker, Larry S. Zweifel, Oline K. Rønnekleiv, Martin J. Kelly
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101645- (2022)
Objective: Proopiomelanocortin (POMC) neurons are the key anorexigenic hypothalamic neuron for integrating metabolic cues to generate the appropriate output for maintaining energy homeostasis and express the requisite channels as a perfect synaptic i
Externí odkaz:
https://doaj.org/article/6c8f4be480964addb3b17dc712cb716d
Autor:
Joseph F. Quinn, Martin J. Kelly, Christopher J. Harris, Wyatt Hack, Nora E. Gray, Veronika Kulik, Zoe Bostick, Barbara H. Brumbach, Philip F. Copenhaver
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105888- (2022)
Based on previous evidence that the non-steroidal estrogen receptor modulator STX mitigates the effects of neurotoxic Amyloid-β (Aβ) in vitro, we have evaluated its neuroprotective benefits in a mouse model of Alzheimer's disease. Cohorts of 5XFAD
Externí odkaz:
https://doaj.org/article/782f7a69b4644a658b5e92462ffc06b9
Autor:
Todd L. Stincic, Martha A. Bosch, Avery C. Hunker, Barbara Juarez, Ashley M. Connors, Larry S. Zweifel, Oline K. Rønnekleiv, Martin J. Kelly
Publikováno v:
Molecular Metabolism, Vol 49, Iss , Pp 101218- (2021)
Objective: Arcuate nucleus neuropeptide Y/agouti-related peptide (NPY/AgRP) neurons drive ingestive behavior. The M-current, a subthreshold non-inactivating potassium current, plays a critical role in regulating NPY/AgRP neuronal excitability. Fastin
Externí odkaz:
https://doaj.org/article/fb095b3020044ae88ead4c1b4cac825f
Autor:
Jian Qiu, Heidi M Rivera, Martha A Bosch, Stephanie L Padilla, Todd L Stincic, Richard D Palmiter, Martin J Kelly, Oline K Rønnekleiv
Publikováno v:
eLife, Vol 7 (2018)
The neuropeptides tachykinin2 (Tac2) and kisspeptin (Kiss1) in hypothalamic arcuate nucleus Kiss1 (Kiss1ARH) neurons are essential for pulsatile release of GnRH and reproduction. Since 17β-estradiol (E2) decreases Kiss1 and Tac2 mRNA expression in K
Externí odkaz:
https://doaj.org/article/8c43e44e4ebd4186b9a91911319ae1ba
Autor:
Jian Qiu, Martin J. Kelly, Ashley M. Connors, Stefanie Kaech Petrie, Todd L. Stincic, Oline K. Rønnekleiv, Martha A. Bosch
Publikováno v:
The Journal of Neuroscience. 41:9688-9701
Kisspeptin (Kiss1) neurons are essential for reproduction, but their role in the control of energy balance and other homeostatic functions remains unclear. High-frequency firing of hypothalamic arcuate Kiss1 (Kiss1ARH) neurons releases kisspeptin int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d23591cfc18004e6f01d22e55e03543
https://doi.org/10.1523/jneurosci.0622-21.2021
https://doi.org/10.1523/jneurosci.0622-21.2021
Autor:
Todd L. Stincic, Martin J. Kelly
Publikováno v:
J Neuroendocrinol
Pregnancy is energetically demanding and, therefore, by necessity reproduction and energy balance are inextricably linked. With insufficient or excessive energy stores a female is liable to suffer complications during pregnancy or produce unhealthy o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474a1f4b033d7cc19f41332ba8a26672
https://europepmc.org/articles/PMC10228899/
https://europepmc.org/articles/PMC10228899/
Autor:
Jian Qiu, Casey C Nestor, Chunguang Zhang, Stephanie L Padilla, Richard D Palmiter, Martin J Kelly, Oline K Rønnekleiv
Publikováno v:
eLife, Vol 5 (2016)
Kisspeptin (Kiss1) and neurokinin B (NKB) neurocircuits are essential for pubertal development and fertility. Kisspeptin neurons in the hypothalamic arcuate nucleus (Kiss1ARH) co-express Kiss1, NKB, dynorphin and glutamate and are postulated to provi
Externí odkaz:
https://doaj.org/article/aaa722b0f09c4914835ef0f2f9847498
Publikováno v:
Endocrinology
Hypothalamic kisspeptin (Kiss1) neurons provide indispensable excitatory transmission to gonadotropin-releasing hormone (GnRH) neurons for the coordinated release of gonadotropins, estrous cyclicity, and ovulation. But maintaining reproductive functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036104445954bb91c3928e4a23ec2731
https://europepmc.org/articles/PMC8758343/
https://europepmc.org/articles/PMC8758343/
Publikováno v:
eNeuro
Kisspeptin (Kiss1) neurons provide indispensable excitatory input to gonadotropin-releasing hormone (GnRH) neurons, which is important for the coordinated release of gonadotropins, estrous cyclicity and ovulation. However, Kiss1 neurons also send pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9edb63a8dca9904a38b8b231f22e383b
http://europepmc.org/articles/PMC8354717
http://europepmc.org/articles/PMC8354717