Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Martin J Hessner"'
Autor:
Kirkwood A Pritchard, Xigang Jing, Michelle Teng, Clive Wells, Shuang Jia, Adeleye J Afolayan, Jason Jarzembowski, Billy W Day, Stephen Naylor, Martin J Hessner, G Ganesh Konduri, Ru-Jeng Teng
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0269564 (2022)
Myeloperoxidase (MPO), oxidative stress (OS), and endoplasmic reticulum (ER) stress are increased in the lungs of rat pups raised in hyperoxia, an established model of bronchopulmonary dysplasia (BPD). However, the relationship between OS, MPO, and E
Externí odkaz:
https://doaj.org/article/0e0e60295b3e42c7bc4e0afe473ef142
Autor:
Anna Palatnik, Shuyun Ye, Christina Kendziorski, Marissa Iden, Jessica S Zigman, Martin J Hessner, Janet S Rader
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193687 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0181242.].
Externí odkaz:
https://doaj.org/article/e5038b14157543cda52fac2e86ca9a2f
Autor:
Angela M Henschel, Susanne M Cabrera, Mary L Kaldunski, Shuang Jia, Rhonda Geoffrey, Mark F Roethle, Vy Lam, Yi-Guang Chen, Xujing Wang, Nita H Salzman, Martin J Hessner
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190351 (2018)
Environmental changes associated with modern lifestyles may underlie the rising incidence of Type 1 diabetes (T1D). Our previous studies of T1D families and the BioBreeding (BB) rat model have identified a peripheral inflammatory state that is associ
Externí odkaz:
https://doaj.org/article/8069ac9084344b759a849304ae2c4684
Autor:
Simon E Regnell, Martin J Hessner, Shuang Jia, Lina Åkesson, Hans Stenlund, Thomas Moritz, Daria La Torre, Åke Lernmark
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171372 (2017)
Type 1 diabetes is associated with abberations of fat metabolism before and after the clinical onset of disease. It has been hypothesized that the absence of the effect of insulin in the liver contributes to reduced hepatic fat synthesis. We measured
Externí odkaz:
https://doaj.org/article/7c49fd896a30464f8ddd9eec1d6dabc5
Autor:
Anna Palatnik, Shuyun Ye, Christina Kendziorski, Marissa Iden, Jessica S Zigman, Martin J Hessner, Janet S Rader
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181242 (2017)
Tumor cells that escape local tissue control can convert inflammatory cells from tumor suppressors to tumor promoters. Moreover, soluble immune-modulating factors secreted from the tumor environment can be difficult to identify in patient serum due t
Externí odkaz:
https://doaj.org/article/96dc36ec380244d2ab18e700e847af85
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152662 (2016)
In type 1 diabetes (T1D), β-cell loss is silent during disease progression. Methylation-sensitive quantitative real-time PCR (qPCR) of β-cell-derived DNA in the blood can serve as a biomarker of β-cell death in T1D. Amylin is highly expressed by
Externí odkaz:
https://doaj.org/article/03ee49d3aa814d6d8258aa03677d5235
Autor:
Hai Nguyen, David Arribas-Layton, I-Ting Chow, Cate Speake, William W. Kwok, Martin J. Hessner, Carla J. Greenbaum, Eddie A. James
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionPrevious studies verify the formation of enzymatically post-translationally modified (PTM) self-peptides and their preferred recognition by T cells in subjects with type 1 diabetes (T1D). However, questions remain about the relative preva
Externí odkaz:
https://doaj.org/article/176aa63aeeca4531b95bd9d0a26130c9
Autor:
Pinar Sargin, Mark F. Roethle, Shuang Jia, Tarun Pant, Ashley E. Ciecko, Samantha N. Atkinson, Nita H. Salzman, Ru-Jeng Teng, Yi-Guang Chen, Susanne M. Cabrera, Martin J. Hessner
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The increasing incidence of Type 1 diabetes has coincided with the emergence of the low-fiber, high-gluten Western diet and other environmental factors linked to dysbiosis. Since Lactiplantibacillus plantarum 299 v (Lp299v) supplementation improves g
Externí odkaz:
https://doaj.org/article/04e49acff871446096d9b0058aa801e5
CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons
Autor:
Xi Zhang, Camille M. Moore, Laura D. Harmacek, Joanne Domenico, Vittobai Rashika Rangaraj, Justin E. Ideozu, Jennifer R. Knapp, Katherine J. Woods, Stephanie Jump, Shuang Jia, Jeremy W. Prokop, Russell Bowler, Martin J. Hessner, Erwin W. Gelfand, Hara Levy
Publikováno v:
JCI Insight, Vol 7, Iss 6 (2022)
Cystic fibrosis (CF) is an inherited disorder caused by biallelic mutations of the CF transmembrane conductance regulator (CFTR) gene. Converging evidence suggests that CF carriers with only 1 defective CFTR copy are at increased risk for CF-related
Externí odkaz:
https://doaj.org/article/a63d56dde4aa4e118ea14046497fc7b7
Autor:
Aditi Narsale, Breanna Lam, Rosa Moya, TingTing Lu, Alessandra Mandelli, Irene Gotuzzo, Benedetta Pessina, Gianmaria Giamporcaro, Rhonda Geoffrey, Kerry Buchanan, Mark Harris, Anne-Sophie Bergot, Ranjeny Thomas, Martin J. Hessner, Manuela Battaglia, Elisavet Serti, Joanna D. Davies
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
Transient partial remission, a period of low insulin requirement experienced by most patients soon after diagnosis, has been associated with mechanisms of immune regulation. A better understanding of such natural mechanisms of immune regulation might
Externí odkaz:
https://doaj.org/article/20ba8c4ce6b4454ea7c69dca229e3557