Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Martin J Elhay"'
Autor:
David R. Powell, Martin J Elhay, Els N.T. Meeusen, Fernando J. Rossello, Michael John de Veer, Melanie R Neeland
Publikováno v:
Immunology
Summary Vaccine formulations incorporating innate immune stimulants are highly immunogenic; however, the biological signals that originate in the peripheral tissues at the site of injection and are transmitted to the local lymph node to induce immuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2537d0cdabd1d091273f6ff41734a9cb
https://doi.org/10.1111/imm.12401
https://doi.org/10.1111/imm.12401
Autor:
Martin J Elhay, Els N.T. Meeusen, Melanie R Neeland, Paul Harrison, Jill Louise Pleasance, Michael John de Veer, Melissa Louise Burke
Publikováno v:
Innate Immunity. 20:501-510
Many modern vaccines use defined adjuvants to stimulate the innate immune system and shape the adaptive immune response. The exact nature of these innate signals and whether immune differentiation can originate within the periphery is not known. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb3fa643440fbbca21280498b43edd2
https://doi.org/10.1177/1753425913501213
https://doi.org/10.1177/1753425913501213
Autor:
Jackie Nathanielsz, Martin J Elhay, Melanie R Neeland, Jill Louise Pleasance, Michael John de Veer, Elza Nicole Theresia Meeusen, Melissa Louise Burke
Publikováno v:
Vaccine. 31:1012-1018
a b s t r a c t After vaccination, innate cell populations transport antigen from the tissue, via the afferent lymphatic vessels, into the local lymph node where they provide critical signals for the generation of an adap- tive immune response. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc38c6e5017b0683fdfffb21b9466d4f
https://doi.org/10.1016/j.vaccine.2012.12.049
https://doi.org/10.1016/j.vaccine.2012.12.049
Publikováno v:
Vaccine. 28:6597-6602
Aluminium adjuvants are potent enhancers of immune responses. Despite being a component in most human and animal vaccines, their specific mode of action remains elusive. We have used a sheep lymphatic cannulation model to directly measure the traffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bbe32b4a252e40c7c3ecba0478b93b
https://doi.org/10.1016/j.vaccine.2010.07.056
https://doi.org/10.1016/j.vaccine.2010.07.056
Publikováno v:
Vaccine. 32(47)
Vaccine formulations administered in the periphery must activate naive immune cells within the lymph node. In this study, we have directly cannulated the ovine lymphatic vessels to investigate the cellular and molecular mechanisms that transfer infor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47f8d13c5de4bc334c72260cedf1665
https://pubmed.ncbi.nlm.nih.gov/25280435
https://pubmed.ncbi.nlm.nih.gov/25280435
Autor:
Lise Ostergaard Brandt, Peter Henrik Andersen, Ida Rosenkrands, Erik B. Lindblad, Martin J Elhay
Publikováno v:
Infection and Immunity. 68:791-795
The ESAT-6 antigen fromMycobacterium tuberculosisis a dominant target for cell-mediated immunity in the early phase of tuberculosis (TB) in TB patients as well as in various animal models. The purpose of our study was to evaluate the potential of ESA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f46d17de02b14e5553220af99d6a8c
https://doi.org/10.1128/iai.68.2.791-795.2000
https://doi.org/10.1128/iai.68.2.791-795.2000
Autor:
Martin J Elhay, Peter Andersen, Susanne Jacobsen, Ida Rosenkrands, Karin Weldingh, Peter Birk Rasmussen
Publikováno v:
Infection and Immunity. 66:3492-3500
Culture filtrate from Mycobacterium tuberculosis contains molecules which promote high levels of protective immunity in animal models of subunit vaccination against tuberculosis. We have used two-dimensional electrophoresis for analysis and purificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4df18cfb682564a8846bb08e0b994d5
https://doi.org/10.1128/iai.66.8.3492-3500.1998
https://doi.org/10.1128/iai.66.8.3492-3500.1998
Autor:
Martin J Elhay, Peter Andersen
Publikováno v:
Immunology and Cell Biology. 75:595-603
Tuberculosis remains one of the most important threats to world health. Current vaccination and prevention strategies are inadequate and there is an urgent need for a new vaccine. The current vaccine bacille Calmette-Guérin (BCG), is unable to prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31220813f0e9c59c56653a61b1bc31b3
https://doi.org/10.1038/icb.1997.94
https://doi.org/10.1038/icb.1997.94
Autor:
Jayne Sherrard, Joanna Kemp, Sarah Preston, Troy Morgan Kraska, Martin J Elhay, David Piedrafita, Michael John de Veer, Elza Nicole Theresia Meeusen
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78357 (2013)
PLoS ONE
PLoS ONE
It has recently been recognised that vaccine adjuvants play a critical role in directing the nature of a vaccine induced effector response. In the present study, several adjuvants were evaluated for their ability to protect sheep after field vaccinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52afe6c6653c299ec74df61b6acff27c
http://europepmc.org/articles/PMC3804492?pdf=render
http://europepmc.org/articles/PMC3804492?pdf=render
Publikováno v:
International Journal for Parasitology. 26:835-842
Successful vaccination against any potential pathogen is critically dependent on inducing an appropriate immune response. The pivotal role of cytokines in the immune response to vaccination suggests that non-protective responses or responses that exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ef601540ec75239135374b58f4a131
https://doi.org/10.1016/s0020-7519(96)80052-x
https://doi.org/10.1016/s0020-7519(96)80052-x