Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Martin Hruda"'
Autor:
Daniela Šimčíková, Dominik Gardáš, Kateřina Hložková, Martin Hruda, Petr Žáček, Lukáš Rob, Petr Heneberg
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Background Hexokinases (HKs) are well-studied enzymes catalyzing the first step of glycolysis. However, non-canonical regulatory roles of HKs are still incompletely understood. Here, we hypothesized that HKs comprise one of the missing links
Externí odkaz:
https://doaj.org/article/8260590dcb464ebea69b15362dc8bd49
Autor:
Karolina Seborova, Viktor Hlavac, Petr Holy, Sunniva S. Bjørklund, Thomas Fleischer, Lukas Rob, Martin Hruda, Jiri Bouda, Marcela Mrhalova, Mohammad Moufaq Khatar Al Obeed Allah, Pavel Vodicka, Ondrej Fiala, Pavel Soucek, Vessela N. Kristensen, Ludmila Vodickova, Radka Vaclavikova
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Epithelial ovarian carcinoma (EOC) is known for high mortality due to diagnosis at advanced stages and frequent therapy resistance. Previous findings suggested that the DNA repair system is involved in the therapeutic response of cancer patients and
Externí odkaz:
https://doaj.org/article/4d3c2d1b733a4311bfac5bc44475ebba
Autor:
Karolina Seborova, Radka Vaclavikova, Pavel Soucek, Katerina Elsnerova, Alena Bartakova, Petr Cernaj, Jiri Bouda, Lukas Rob, Martin Hruda, Pavel Dvorak
Publikováno v:
Cancer Medicine, Vol 8, Iss 2, Pp 606-616 (2019)
Abstract Introduction Ovarian cancer (OC) represents a serious disease with high mortality and lack of efficient predictive and prognostic biomarkers. ATP‐binding cassette (ABC) proteins constitute a large family dedicated to active transmembrane t
Externí odkaz:
https://doaj.org/article/4226b8e44ddc49938d5292df14cafd04
Autor:
Karolina Seborova, Alzbeta Kloudova-Spalenkova, Kamila Koucka, Petr Holy, Marie Ehrlichova, Changwei Wang, Iwao Ojima, Iveta Voleska, Petr Daniel, Kamila Balusikova, Michael Jelinek, Jan Kovar, Lukas Rob, Martin Hruda, Marcela Mrhalova, Pavel Soucek, Radka Vaclavikova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 73 (2021)
The main problem precluding successful therapy with conventional taxanes is de novo or acquired resistance to taxanes. Therefore, novel experimental taxane derivatives (Stony Brook taxanes; SB-Ts) are synthesized and tested as potential drugs against
Externí odkaz:
https://doaj.org/article/77ee0bd6371147ae89d6f2ac8ee5c1f2
Autor:
Helena Robova, Lukas Rob, Michael J. Halaska, Jana Drozenova, Tomas Pichlik, Vit Drochytek, Martin Hruda
Publikováno v:
Gynecologic Oncology. 174:76-79
Autor:
Borek Sehnal, Jaroslav Klat, Petra Herboltova, Jiri Hanacek, Michael Fanta, Petr Valha, Martin Hruda, Ian Vasicka, Michael J. Halaska
Publikováno v:
European Journal of Obstetrics & Gynecology and Reproductive Biology. 276:148-153
Surgical treatment of obese female patients represents a real challenge. Over the last decade, minimally invasive techniques for hysterectomy have emerged. These approaches reduce the invasiveness of standard surgical procedures while maintaining eff
Autor:
Karolina Seborova, Viktor Hlavac, Petr Holy, Sunniva Bjørklund, Thomas Fleischer, Alzbeta Spalenkova, Lukas Rob, Martin Hruda, Petr Cernaj, Jiri Bouda, Vessela N Kristensen, Pavel Soucek, Radka Vaclavikova
Publikováno v:
E-Posters.
Autor:
Martin Hruda, Viktor Hlaváč, Petr Holý, Karolína Šeborová, Radka Václavíková, Marcela Mrhalová, Petr Černaj, Jiří Bouda, Pavel Souček, Lukáš Rob
Publikováno v:
Ovarian cancer.
Autor:
Martin Hruda, Helena Robová, Lukáš Rob, Michael Jiří Halaška, Jana Drozenová, Tomáš Pichlík, Hana Malíková
Publikováno v:
Cervical cancer.
Autor:
Martin Hruda
Publikováno v:
Onkologie. 14:74-77
Incidence malignit v těhotenstvi byla dlouhodobě okrajovou zaležitosti, ale s narůstajicim věkem rodicek v poslednich dekadach roste. Maligni onemocněni v těhotenstvi je komplikaci pro přibližně 20-40/100 000 těhotných žen. Mezi nejcast