Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Martin Hruby"'
Autor:
Yusuf Dölen, Uzi Gileadi, Ji-Li Chen, Michael Valente, Jeroen H. A. Creemers, Eric A. W. Van Dinther, N. Koen van Riessen, Eliezer Jäger, Martin Hruby, Vincenzo Cerundolo, Mustafa Diken, Carl G. Figdor, I. Jolanda M. de Vries
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tumor-specific neoantigens can be highly immunogenic, but their identification for each patient and the production of personalized cancer vaccines can be time-consuming and prohibitively expensive. In contrast, tumor-associated antigens are widely ex
Externí odkaz:
https://doaj.org/article/0cd7f0771f6d416b8ca65394e4472b9d
Autor:
Yusuf Dölen, Michael Valente, Oya Tagit, Eliezer Jäger, Eric A. W. Van Dinther, N. Koen van Riessen, Martin Hruby, Uzi Gileadi, Vincenzo Cerundolo, Carl G. Figdor
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Nanovaccines, co-delivering antigen and invariant natural killer T (iNKT) cell agonists, proved to be very effective in inducing anti-tumor T cell responses due to their exceptional helper function. However, it is known that iNKT cells are not equall
Externí odkaz:
https://doaj.org/article/c812d3d1313e4b30b8812dcd99efb274
Autor:
Maria Camilla Operti, Alexander Bernhardt, Vladimir Sincari, Eliezer Jager, Silko Grimm, Andrea Engel, Martin Hruby, Carl Gustav Figdor, Oya Tagit
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 276 (2022)
Despite the efficacy and potential therapeutic benefits that poly(lactic-co-glycolic acid) (PLGA) nanomedicine formulations can offer, challenges related to large-scale processing hamper their clinical and commercial development. Major hurdles for th
Externí odkaz:
https://doaj.org/article/520ea29edb634f44a4939dd9f2d92bf8
Autor:
Jan Havlik, Vladimira Petrakova, Jan Kucka, Helena Raabova, Dalibor Panek, Vaclav Stepan, Zuzana Zlamalova Cilova, Philipp Reineck, Jan Stursa, Jan Kucera, Martin Hruby, Petr Cigler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Mass production of nanoparticles containing well-controlled structural defects is a challenge. Here the authors demonstrate the feasibility of homogeneous ion irradiation generated in a nuclear reactor, for the preparation of fluorescent nanodiamonds
Externí odkaz:
https://doaj.org/article/d24191b157dd408483a7995aee04b7c0
Autor:
Martin Hruby, Irma Ivette Santana Martínez, Holger Stephan, Pavla Pouckova, Jiri Benes, Petr Stepanek
Publikováno v:
Polymers, Vol 13, Iss 22, p 3969 (2021)
Iron and copper are essential micronutrients needed for the proper function of every cell. However, in excessive amounts, these elements are toxic, as they may cause oxidative stress, resulting in damage to the liver and other organs. This may happen
Externí odkaz:
https://doaj.org/article/9f4c59362f0e453cbcad55855ae255cf
Autor:
Martin Hruby, Khushboo Agrawal, Olivia Policianova, Jiri Brus, Jan Skopal, Pavel Svec, Miroslav Otmar, Petr Dzubak, Petr Stepanek, Marian Hajduch
Publikováno v:
Biomedical Papers, Vol 160, Iss 2, Pp 222-230 (2016)
Background: The archetypal DNA methyltransferase inhibitors, 5-azacytidine (AZA) and 5-aza-2'-deoxycytidine (DAC) are potent antineoplastic agents used in the treatment of mainly, blood malignancies. However, the administration of these drugs is conf
Externí odkaz:
https://doaj.org/article/cbba99dfdc65480fb1ebb674d8b9a70e
Autor:
David Babuka, Kristyna Kolouchova, Ondrej Groborz, Zdenek Tosner, Alexander Zhigunov, Petr Stepanek, Martin Hruby
Publikováno v:
Nanomaterials, Vol 10, Iss 11, p 2231 (2020)
Fluorine-19 MRI is a promising noninvasive diagnostic method. However, the absence of a nontoxic fluorine-19 MRI tracer that does not suffer from poor biodistribution as a result of its strong fluorophilicity is a constant hurdle in the widespread ap
Externí odkaz:
https://doaj.org/article/9a8e315d56804e3183fb68359d26a107
Autor:
Zbynek Novy, Volodymyr Lobaz, Martin Vlk, Jan Kozempel, Petr Stepanek, Miroslav Popper, Jana Vrbkova, Marian Hajduch, Martin Hruby, Milos Petrik
Publikováno v:
Nanomaterials, Vol 10, Iss 9, p 1690 (2020)
Nanoparticles (NPs) represent an emerging platform for diagnosis and treatment of various diseases such as cancer, where they can take advantage of enhanced permeability and retention (EPR) effect for solid tumor accumulation. To improve their colloi
Externí odkaz:
https://doaj.org/article/1a28b2b1d6ac44eab4bdfce3ae04cef0
Autor:
Jakub Hrib, Eva Chylikova Krumbholcova, Miroslava Duskova-Smrckova, Radka Hobzova, Jakub Sirc, Martin Hruby, Jiri Michalek, Jiri Hodan, Petr Lesny, Roman Smucler
Publikováno v:
Polymers, Vol 11, Iss 7, p 1087 (2019)
Self-inflating soft tissue expanders represent a valuable modality in reconstructive surgery. For this purpose, particularly synthetic hydrogels that increase their volume by swelling in aqueous environment are used. The current challenge in the fiel
Externí odkaz:
https://doaj.org/article/b9caceb0afb7422295fa13954999d557
Autor:
Martin Hruby
Publikováno v:
Geoinformatics FCE CTU, Vol 7, Iss 0, Pp 11-30 (2012)
The paper deals with a design of a new raster sub-system intended for modern GIS systems open for client and server operation, database connection and strong application interface (API). Motivation for such a design comes from the current state of AP
Externí odkaz:
https://doaj.org/article/b846c3bea254404988905c38f6fcc830