Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Martin Hosking"'
1
Akademický článek
iPSC-derived NK cells expressing high-affinity IgG Fc receptor fusion CD64/16A to mediate flexible, multi-tumor antigen targeting for lymphoma
Autor: Kate J. Dixon, Kristin M. Snyder, Melissa Khaw, Robert Hullsiek, Zachary B. Davis, Anders W. Matson, Soheila Shirinbak, Bryan Hancock, Ryan Bjordahl, Martin Hosking, Jeffrey S. Miller, Bahram Valamehr, Jianming Wu, Bruce Walcheck
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
IntroductionNK cells can mediate tumor cell killing by natural cytotoxicity and by antibody-dependent cell-mediated cytotoxicity (ADCC), an anti-tumor mechanism mediated through the IgG Fc receptor CD16A (FcγRIIIA). CD16A polymorphisms conferring in
Externí odkaz: https://doaj.org/article/25f0bc6b630e4c64ae1fcc8be73d5e42
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2
Akademický článek
iPSC-derived natural killer cells expressing the FcγR fusion CD64/16A can be armed with antibodies for multitumor antigen targeting
Autor: Jeffrey S Miller, Martin Hosking, Ryan Bjordahl, Bahram Valamehr, Soheila Shirinbak, Zachary Davis, Bryan Hancock, Bruce Walcheck, Kristin M Snyder, Kate J Dixon, Geoffrey Hart, Melissa Khaw, Anders Matson, Jianming Wu
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Background Antibody therapies can direct natural killer (NK) cells to tumor cells, tumor-associated cells, and suppressive immune cells to mediate antibody-dependent cell-mediated cytotoxicity (ADCC). This antigen-specific effector function of human
Externí odkaz: https://doaj.org/article/5fb4875136e348289f045144cde7592c
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4
Akademický článek
A Canadian, retrospective, multicenter experience with selexipag for a heterogeneous group of pediatric pulmonary hypertension patients
Autor: David Youssef, Susan Richards, Sabine Lague, Catherine Sheppard, Jenna Smith, Erika Vorhies, Martin Hosking, Matthew Pietrosanu, Angela Bates
Publikováno v: Frontiers in Pediatrics, Vol 11 (2023)
IntroductionSelexipag, an oral nonprostanoid prostaglandin receptor agonist, has led to reduced morbidity and mortality in adults with pulmonary arterial hypertension (PAH). While the adult literature has been extrapolated to suggest selexipag as an
Externí odkaz: https://doaj.org/article/fe6c2bbc44e74f2e80bed13272e9261a
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5
Akademický článek
Utility and Access to 3-Dimensional Printing in the Context of Congenital Heart Disease: An International Physician Survey Study
Autor: Caroline F. Illmann, BSc, Martin Hosking, MD, Kevin C. Harris, MD, MHSc
Publikováno v: CJC Open, Vol 2, Iss 4, Pp 207-213 (2020)
Background: Three-dimensional (3D) printing is a new technology capable of producing patient-specific 3D cardiac models. Methods: A cross-sectional survey of pediatric cardiologists was conducted. Members of the Canadian Pediatric Cardiology Associat
Externí odkaz: https://doaj.org/article/2e97c2dba8b544ad98d0f1ce9c8494b0
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