Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Martin Holdener"'
Autor:
Selina Christen, Ken Coppieters, Kerstin Rose, Martin Holdener, Monika Bayer, Josef M Pfeilschifter, Edith Hintermann, Matthias G von Herrath, Michel Aurrand-Lions, Beat A Imhof, Urs Christen
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54675 (2013)
Type 1 diabetes (T1D) results from the autoimmune destruction of insulin-producing beta-cells in the pancreas. Recruitment of inflammatory cells is prerequisite to beta-cell-injury. The junctional adhesion molecule (JAM) family proteins JAM-B and JAM
Externí odkaz:
https://doaj.org/article/d685c0b69ec74af4b048df92ec80e458
Autor:
Malte Bachmann, Katharina Horn, Ina Rudloff, Itamar Goren, Martin Holdener, Urs Christen, Nicole Darsow, Klaus-Peter Hunfeld, Ulrike Koehl, Peter Kind, Josef Pfeilschifter, Peter Kraiczy, Heiko Mühl
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001144 (2010)
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine s
Externí odkaz:
https://doaj.org/article/e6c088080be7423fa78c20ce81794829
Autor:
Andreas Bergthaler, Lukas Flatz, Admar Verschoor, Ahmed N Hegazy, Martin Holdener, Katja Fink, Bruno Eschli, Doron Merkler, Rami Sommerstein, Edit Horvath, Marylise Fernandez, André Fitsche, Beatrice M Senn, J. Sjef Verbeek, Bernhard Odermatt, Claire-Anne Siegrist, Daniel D Pinschewer
Publikováno v:
PLoS Biology, Vol 7, Iss 8 (2009)
Externí odkaz:
https://doaj.org/article/ec0219d9772549e08bac957492e2f23a
Autor:
Andreas Bergthaler, Lukas Flatz, Admar Verschoor, Ahmed N Hegazy, Martin Holdener, Katja Fink, Bruno Eschli, Doron Merkler, Rami Sommerstein, Edit Horvath, Marylise Fernandez, André Fitsche, Beatrice M Senn, J Sjef Verbeek, Bernhard Odermatt, Claire-Anne Siegrist, Daniel D Pinschewer
Publikováno v:
PLoS Biology, Vol 7, Iss 4, p e1000080 (2009)
CD8 T cells are recognized key players in control of persistent virus infections, but increasing evidence suggests that assistance from other immune mediators is also needed. Here, we investigated whether specific antibody responses contribute to con
Externí odkaz:
https://doaj.org/article/8a27a9e5804d4df3b1f7cdd8b9062da4
Autor:
Hamed Aissaoui, Martin Holdener, Carmela Gnerre, Kerstin Niggemann, Stefan Reber, Sylvia Richard, Romain Siegrist, Christoph Boss
Publikováno v:
ChemMedChem. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08d96c24bacc9c0e213c72b029c9da27
https://doi.org/10.1002/cmdc.202300007
https://doi.org/10.1002/cmdc.202300007
Autor:
Hervé Farine, Julie Hoerner, Peter M.A. Groenen, Daniel S. Strasser, Martin Holdener, Patricia N. Sidharta, Martine Gehin, Jasper Dingemanse, René Roscher, Jochen Zisowsky
Publikováno v:
European Journal of Molecular and Clinical Medicine, Vol 2, Iss 4-5, Pp 118-125 (2015)
Biomarkers have shown to improve success rates in the development of novel drugs, providing essential information in the early phases of clinical development for decision-making. Chemoattractant receptor-homologous molecule expressed on Th2 cells (CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b4f17496e233b4a4886b9d53b46b88
https://www.ejmcm.com/articles/210
https://www.ejmcm.com/articles/210
Autor:
Martin Holdener, Urs Christen, Monika Bayer, Selina Christen, Josef Pfeilschifter, Dimitrios P. Bogdanos, Janine Ehser, Edith Hintermann
Publikováno v:
Journal of Autoimmunity. 42:39-49
In our novel mouse model for autoimmune hepatitis (AIH), wildtype FVB mice infected with an Adenovirus (Ad) expressing the major AIH autoantigen human cytochrome P450 2D6 (hCYP2D6) show persistent histological and immunological features associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38be5d4678efecf6f8d33b116d9ca05
https://doi.org/10.1016/j.jaut.2012.11.001
https://doi.org/10.1016/j.jaut.2012.11.001
Autor:
Josef Pfeilschifter, Urs Christen, Martin Holdener, Claude Granier, Michael P. Manns, Edith Hintermann, Monika Bayer, Stephanie Loges
Publikováno v:
Journal of Autoimmunity. 37:242-253
Autoimmune hepatitis (AIH) is a serious chronic inflammatory disease of the liver with yet unknown etiology and largely uncertain immunopathology. The hallmark of type 2 AIH is the generation of liver kidney microsomal-1 (LKM-1) autoantibodies, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6495f18be95386d4de7be2d262cec069
https://doi.org/10.1016/j.jaut.2011.06.005
https://doi.org/10.1016/j.jaut.2011.06.005
Publikováno v:
Journal of Autoimmunity. 34:38-44
In this review we want to consider some of the requirements for autoimmune disease to develop and how this may be reproduced in animal models. Besides a genetic predisposition, environmental triggering factors seem to play a central role in the etiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e837cee879ee9f92bf72acb7e9f36d
https://doi.org/10.1016/j.jaut.2009.08.001
https://doi.org/10.1016/j.jaut.2009.08.001
Autor:
Andreas Linke, Itamar Goren, Christoph Schürmann, Martin Holdener, Josef Pfeilschifter, Stefan Frank, Nadine Allmann, Ari Waisman, Nir Yogev
Publikováno v:
The American Journal of Pathology. 175:132-147
Whether the wound macrophage is a key regulatory inflammatory cell type in skin repair has been a matter of debate. A transgenic mouse model mediating inducible macrophage depletion during skin repair has not been used to date to address this questio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e2a92f29b02774bb8c77070f9cac6f
https://doi.org/10.2353/ajpath.2009.081002
https://doi.org/10.2353/ajpath.2009.081002