Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Martin Hey-Mogensen"'
Autor:
Casey L. Quinlan, Irina V. Perevoshchikova, Martin Hey-Mogensen, Adam L. Orr, Martin D. Brand
Publikováno v:
Redox Biology, Vol 1, Iss 1, Pp 304-312 (2013)
Mitochondrial radical production is important in redox signaling, aging and disease, but the relative contributions of different production sites are poorly understood. We analyzed the rates of superoxide/H2O2 production from different defined sites
Externí odkaz:
https://doaj.org/article/3405ed2232b1433ba604656945b5da86
Autor:
Martin Hey-Mogensen, Joachim Nielsen, Niels Ørtenblad, Kasper Degn Gejl, Charlotte Suetta, Hans-Christer Holmberg, Peter Krustrup, Coen P. H. Elemans
Publikováno v:
The Journal of Physiology. 595:2839-2847
Mitochondrial energy production involves the movement of protons down a large electrochemical gradient via ATP synthase located on the folded inner membrane, known as cristae. In mammalian skeletal ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10e0a53e9ae06095b04fbcead600ff51
https://doi.org/10.1113/jp273040
https://doi.org/10.1113/jp273040
Autor:
Martin Gram, Martin Hey-Mogensen, Andreas Vigelsø, Jørn Wulff Helge, Flemming Dela, Takashi Yokota
Publikováno v:
The Journal of Physiology. 593:4011-4027
Currently, it is not known whether impaired mitochondrial function contributes to human ageing or whether potential impairments in mitochondrial function with age are secondary to physical inactivity. The present study investigated mitochondrial resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b8328d32dd0939f662e482c4cf63ca4
https://doi.org/10.1113/jp270211
https://doi.org/10.1113/jp270211
Autor:
Irina V. Perevoshchikova, Casey L. Quinlan, Martin Hey-Mogensen, Renata L.S. Goncalves, Martin D. Brand
Publikováno v:
Journal of Biological Chemistry. 290:209-227
The sites and rates of mitochondrial production of superoxide and H2O2 in vivo are not yet defined. At least 10 different mitochondrial sites can generate these species. Each site has a different maximum capacity (e.g. the outer quinol site in comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f513df7f4e88b89c2e53325e7c84a3
https://doi.org/10.1074/jbc.m114.619072
https://doi.org/10.1074/jbc.m114.619072
Autor:
Martin Hey-Mogensen, Trine R. Clausen
Publikováno v:
Current Diabetes Reviews. 13
Introduction The mitochondrion plays a critical role in cellular energy metabolism. For this reason it is considered as a plausible target for the treatment of metabolic diseases such as obesity and type-2 diabetes. Although several mitochondrial mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7220eeeffd4863d00eff751e67f546
https://doi.org/10.2174/1573399812666160217122827
https://doi.org/10.2174/1573399812666160217122827
Autor:
Nagendra Yadava, Martin Hey-Mogensen, Martin D. Brand, Casey L. Quinlan, Renata L.S. Goncalves, Victoria I. Bunik
Publikováno v:
Journal of Biological Chemistry. 289:8312-8325
Several flavin-dependent enzymes of the mitochondrial matrix utilize NAD(+) or NADH at about the same operating redox potential as the NADH/NAD(+) pool and comprise the NADH/NAD(+) isopotential enzyme group. Complex I (specifically the flavin, site I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c953316c5b1c9199f3e4f9d89b08b1f8
https://doi.org/10.1074/jbc.m113.545301
https://doi.org/10.1074/jbc.m113.545301
Autor:
Jørn Wulff Helge, Nis Stride, Lia E. Bang, Flemming Dela, Christina Neigaard Hansen, Steen Larsen, Henning Bundgaard, Lars Bo Nielsen, Martin Hey-Mogensen
Publikováno v:
Journal of the American College of Cardiology. 61(1):44-53
Background A prevalent side effect of statin therapy is muscle pain, and yet the basic mechanism behind it remains unknown. We hypothesize that a statin-induced reduction in muscle Q10 may attenuate mitochondrial OXPHOS capacity, which may be an unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e9dc2169df98dfa2ca35b7c39e44ec
Autor:
Flemming Dela, Christina Neigaard Hansen, Flemming Wibrand, Joachim Nielsen, Lars Bo Nielsen, Steen Larsen, Martin Hey-Mogensen, Jørn Wulff Helge, Henrik Daa Schrøder, Nis Stride, Robert Boushel
Publikováno v:
The Journal of Physiology. 590:3349-3360
Skeletal muscle mitochondrial content varies extensively between human subjects. Biochemical measures of mitochondrial proteins, enzyme activities and lipids are often used as markers of mitochondrial content and muscle oxidative capacity (OXPHOS). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfdcd5192e638f05808b1fa4e8f66e37
https://doi.org/10.1113/jphysiol.2012.230185
https://doi.org/10.1113/jphysiol.2012.230185
Publikováno v:
Acta Physiologica. 204:354-361
Aim: Mitochondrial dysfunction has been suggested to play a significant role in obesity and insulin resistance. The aim of the present study was to investigate if changes in obesity and insulin resistance were related to similar changes in mitochondr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b6e136a1e591b71eda9c843f564725b
https://doi.org/10.1111/j.1748-1716.2011.02347.x
https://doi.org/10.1111/j.1748-1716.2011.02347.x
Autor:
Martin Gram, Vilhelm A. Bohr, Martin Borch Jensen, Martin Hey-Mogensen, Morten Scheibye-Knudsen, Flemming Dela, Christina Neigaard Hansen, Michael T. Lund
Key points The present study utilized a novel method aiming to investigate mitochondrial function in human skeletal muscle at submaximal levels and at a predefined membrane potential. The effect of age and training status was investigated using a cro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08839544c3d7ff414c7fbcdfc93a0b78
https://europepmc.org/articles/PMC4575582/
https://europepmc.org/articles/PMC4575582/
