Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Martin Hermansson"'
Autor:
Martina B. Lorey, Amer Youssef, Lauri Äikäs, Matthew Borrelli, Martin Hermansson, Julia M. Assini, Aapeli Kemppainen, Hanna Ruhanen, Maija Ruuth, Sampsa Matikainen, Petri T. Kovanen, Reijo Käkelä, Michael B. Boffa, Marlys L. Koschinsky, Katariina Öörni
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionLipoprotein(a) (Lp(a)) is an LDL-like particle with an additional apolipoprotein (apo)(a) covalently attached. Elevated levels of circulating Lp(a) are a risk factor for atherosclerosis. A proinflammatory role for Lp(a) has been proposed,
Externí odkaz:
https://doaj.org/article/e718ebe0203e44b68e68438c5b4d9562
Autor:
Philip Hallenborg, Benjamin Anderschou Holbech Jensen, Even Fjære, Rasmus Koefoed Petersen, Mohammed-Samir Belmaâti, Sarah Søndergård Rasmussen, Jon Petur Gunnarsson, Pernille Lauritzen, Kenneth King Yip Cheng, Martin Hermansson, Si Brask Sonne, Christer S. Ejsing, Aimin Xu, Irina Kratchmarova, Marcus Krüger, Lise Madsen, Karsten Kristiansen, Blagoy Blagoev
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The intimate association between obesity and type II diabetes urges for a deeper understanding of adipocyte function. We and others have previously delineated a role for the tumor suppressor p53 in adipocyte biology. Here, we show that mice
Externí odkaz:
https://doaj.org/article/40be2ce071a64faf8d38428ae1f155cb
Autor:
Bing Peng, Dominik Kopczynski, Brian S. Pratt, Christer S. Ejsing, Bo Burla, Martin Hermansson, Peter Imre Benke, Sock Hwee Tan, Mark Y. Chan, Federico Torta, Dominik Schwudke, Sven W. Meckelmann, Cristina Coman, Oliver J. Schmitz, Brendan MacLean, Mailin-Christin Manke, Oliver Borst, Markus R. Wenk, Nils Hoffmann, Robert Ahrends
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Targeted mass spectrometry enables reproducible and accurate lipid quantification but dedicated software tools to develop targeted lipidomics assays are lacking. Here, the authors develop a targeted lipidomics workbench and lipid knowledgebase for th
Externí odkaz:
https://doaj.org/article/cf125a979bd74b198ac9797a20846f29
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 3, Pp 182-187 (2020)
Abstract Mammalian cells maintain the complex glycerophospholipid (GPL) class compositions of their various membranes within close limits because this is essential to their well‐being or viability. Surprisingly, however, it is still not understood
Externí odkaz:
https://doaj.org/article/c60e25a3381043ef80631d6b8c813f82
Autor:
Fernando Martínez-Montañés, Albert Casanovas, Richard R. Sprenger, Magdalena Topolska, David L. Marshall, Marta Moreno-Torres, Berwyck L.J. Poad, Stephen J. Blanksby, Martin Hermansson, Ole N. Jensen, Christer S. Ejsing
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108024- (2020)
Summary: The ability to remodel lipid metabolism under changing conditions is pivotal for cellular functionality and homeostasis. Here, we characterize the regulatory landscape of phosphorylation-based signaling events across the life cycle of Saccha
Externí odkaz:
https://doaj.org/article/c5ea7ca592024eb0a1b9cd19cf2ab979
Autor:
Sihui Wang, Fatima-Zahra Idrissi, Martin Hermansson, Alexandra Grippa, Christer S. Ejsing, Pedro Carvalho
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Lipid droplets (LDs) and peroxisomes both emerge from the endoplasmic reticulum (ER). Here, the authors show that yeast Seipin and Pex30 proteins act together to regulate budding of these organelles from the same subdomain of the ER.
Externí odkaz:
https://doaj.org/article/41f77d38f6a44557a6cd2e203937e85f
Publikováno v:
Bio-Protocol, Vol 7, Iss 9 (2017)
Glycerophospholipids consist of a glycerophosphate backbone to which are esterified two acyl chains and a polar head group. The head group (e.g., choline, ethanolamine, serine or inositol) defines the glycerophospholipid class, while the acyl chains
Externí odkaz:
https://doaj.org/article/62a3d6f8d9084830a77296da245d331f
Autor:
Josch K Pauling, Martin Hermansson, Jürgen Hartler, Klaus Christiansen, Sandra F Gallego, Bing Peng, Robert Ahrends, Christer S Ejsing
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188394 (2017)
Advances in mass spectrometry-based lipidomics have in recent years prompted efforts to standardize the annotation of the vast number of lipid molecules that can be detected in biological systems. These efforts have focused on cataloguing, naming and
Externí odkaz:
https://doaj.org/article/116b0c47a2a54f21b3dcbca12c694c4e
Publikováno v:
Biomolecules, Vol 9, Iss 1, p 7 (2018)
Total fatty acid analysis is a routine method in many areas, including lipotyping of individuals in personalized medicine, analysis of foodstuffs, and optimization of oil production in biotechnology. This analysis is commonly done by converting fatty
Externí odkaz:
https://doaj.org/article/06a6805163a84a7d9eba97c87058a67e
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 12, Pp 3533-3541 (2010)
Previous studies indicate that methyl-β-cyclodextrin (meβ-CD) can greatly enhance translocation of long-chain phospholipids from vesicles to cells in culture, which is very useful when studying, e.g., phospholipid metabolism and trafficking. Howeve
Externí odkaz:
https://doaj.org/article/1e0de7984b80415c9630261033641adb