Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Martin Held"'
Autor:
Zhenzhen Zhang, Liang Gao, Alexander Boes, Barbara Bajer, Johanna Stotz, Lina Apitius, Felix Jakob, Erik S. Schneider, Evgeni Sperling, Martin Held, Thomas Emmler, Ulrich Schwaneberg, Volker Abetz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Continuous-flow biocatalysis utilizing immobilized enzymes emerged as a sustainable route for chemical synthesis. However, inadequate biocatalytic efficiency from current flow reactors, caused by non-productive enzyme immobilization or enzym
Externí odkaz:
https://doaj.org/article/d99ffd88bb234f94a89aa0bf68178d4d
Publikováno v:
CHIMIA, Vol 77, Iss 6 (2023)
Detailed preclinical characterization of metabolites formed in vivo from candidate drug substances is mandatory prior to the initiation of clinical trials. Therefore, inexpensive and efficient methods for drug metabolite synthesis are of high importa
Externí odkaz:
https://doaj.org/article/c275314c5a034df495533fdb43a633d6
Autor:
Philipp Koch, Steven Schmitt, Alexander Heynisch, Anja Gumpinger, Irene Wüthrich, Marina Gysin, Dimitri Shcherbakov, Sven N. Hobbie, Sven Panke, Martin Held
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-21 (2022)
Abstract Background Intracellularly active antimicrobial peptides are promising candidates for the development of antibiotics for human applications. However, drug development using peptides is challenging as, owing to their large size, an enormous s
Externí odkaz:
https://doaj.org/article/755df7666caf46a98e4895ca26a9e51a
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The number of newly approved antimicrobial compounds has been steadily decreasing over the past 50 years emphasizing the need for novel antimicrobial substances. Here we present Me x, a method for the high-throughput discovery of novel antim
Externí odkaz:
https://doaj.org/article/4840e6ec536543a186b250c05533d95d
Publikováno v:
Data in Brief, Vol 31, Iss , Pp 105984- (2020)
The Salzburg Database is a repository of polygonal areas of various classes and sizes, with and without holes. Positive weights are assigned to all edges of all polygons. We introduce this collection and describe the generators that produced its poly
Externí odkaz:
https://doaj.org/article/535c743b2ac8463c97bb55fd90873893
Publikováno v:
Membranes, Vol 11, Iss 3, p 174 (2021)
As a promising material for CO2/N2 separation, PolyActiveTM can be used as a separation layer in thin-film composite membranes (TFCM). Prior studies focused on the modification of PolyActiveTM using low-molecular-weight additives. In this study, the
Externí odkaz:
https://doaj.org/article/845532757a7a4739874b26fa850096b2
Publikováno v:
CAD'23.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e40614502aa2c7f65db00903b2e3aa5
https://doi.org/10.14733/cadconfp.2023.174-178
https://doi.org/10.14733/cadconfp.2023.174-178
Publikováno v:
ACM Journal of Experimental Algorithmics. 27:1-12
Our work on the Computational Geometry Challenge 2019 on area-optimal polygonizations is based on two key components: (1) sampling the search space to obtain initial polygonizations and (2) optimizing such a polygonizations. Among other heuristics fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02cf8bce59f466e836aa57a9f2ef6e97
https://doi.org/10.1145/3500913
https://doi.org/10.1145/3500913
Autor:
Martin Held, Peter Palfrader
Publikováno v:
Computer-Aided Design and Applications. 19:967-976
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11f27d9338bdc1f0af5da1d7d3c04f39
https://doi.org/10.14733/cadaps.2022.967-976
https://doi.org/10.14733/cadaps.2022.967-976
Publikováno v:
Green Chemistry, 24
We demonstrate a novel one-pot biocatalytic process for the preparation of a versatile chemical intermediate, 2,6-bis(hydroxymethyl)pyridine, from naturally-occurring 2,6-lutidine using recombinant microbial whole cells as a catalysts. After scale up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5ab0bcc316384ccf4edff25a8779b0
https://doi.org/10.1039/d2gc00333c
https://doi.org/10.1039/d2gc00333c