Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Martin Helan"'
Publikováno v:
Renal Failure, Vol 45, Iss 1 (2023)
AbstractAcute kidney injury (AKI) is associated with impaired outcomes in critically ill COVID-19 patients. However, the prognostic significance of early AKI is poorly described. We aimed to determine whether AKI on admission to the intensive care un
Externí odkaz:
https://doaj.org/article/a0945fec4db6447fae201a371dc47ced
Autor:
Martin Helan, Jan Malaska, Josef Tomandl, Jiri Jarkovsky, Katerina Helanova, Klara Benesova, Michal Sitina, Milan Dastych, Tomas Ondrus, Monika Pavkova Goldbergova, Roman Gal, Petr Lokaj, Marie Tomandlova, Jiri Parenica
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 640 (2022)
Septic shock is a major cause of mortality in ICU patients, its pathophysiology is complex and not properly understood. Oxidative stress seems to be one of the most important mechanisms of shock progression to multiple organ failure. In the present p
Externí odkaz:
https://doaj.org/article/1423f386f1bd4135b46c9a37a3d82924
Autor:
William Hartman, Martin Helan, Dan Smelter, Venkatachalem Sathish, Michael Thompson, Christina M Pabelick, Bruce Johnson, Y S Prakash
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0129489 (2015)
Hypoxia effects on pulmonary artery structure and function are key to diseases such as pulmonary hypertension. Recent studies suggest that growth factors called neurotrophins, particularly brain-derived neurotrophic factor (BDNF), can influence lung
Externí odkaz:
https://doaj.org/article/be0865b199aa4b80939929d706cbab9a
Autor:
Ivana Andrejčinová, Gabriela Blažková, Ioanna Papatheodorou, Kamila Bendíčková, Veronika Bosáková, Monika Skotáková, Roman Panovský, Lukáš Opatřil, Ondřej Vymazal, Petra Kovačovicová, Vladimír Šrámek, Martin Helán, Marcela Hortová-Kohoutková, Jan Frič
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25938- (2024)
COVID-19 manifestation is associated with a strong immune system activation leading to inflammation and subsequently affecting the cardiovascular system. The objective of the study was to reveal possible interconnection between prolongated inflammati
Externí odkaz:
https://doaj.org/article/f617ca2ba0344a22bafd2c3c94b44616
Autor:
Marcela Hortová-Kohoutková, Monika Skotáková, Isaac G. Onyango, Miriam Slezáková, Roman Panovský, Lukáš Opatřil, Peter Slanina, Marco De Zuani, Ondřej Mrkva, Ivana Andrejčinová, Petra Lázničková, Martina Dvončová, Alexandra Mýtniková, Vaughn Ostland, Michal Šitina, Gorazd B. Stokin, Vladimír Šrámek, Marcela Vlková, Martin Helán, Jan Frič
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMajor clinically relevant inflammatory events such as septic shock and severe COVID-19 trigger dynamic changes in the host immune system, presenting promising candidates for new biomarkers to improve precision diagnostics and patient stra
Externí odkaz:
https://doaj.org/article/04c0cc079aed47a5a83b613a13f68454
Autor:
Veronika Tomášková, Alexandra Mýtniková, Marcela Hortová Kohoutková, Ondřej Mrkva, Monika Skotáková, Michal Šitina, Kateřina Helánová, Jan Frič, Jiří Pařenica, Vladimír Šrámek, Martin Helán
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Sepsis is a clinical syndrome characterized by a dysregulated response to infection. It represents a leading cause of mortality in ICU patients worldwide. Although sepsis is in the point of interest of research for several decades, its clinical manag
Externí odkaz:
https://doaj.org/article/599daca0805a48cc88ce354abf90785d
Autor:
Martin Helán, Martin Ráb, Vladimír Šrámek, Jiří Vaníček, Robert Staffa, Ondřej Volný, Pavel Suk
Publikováno v:
EJVES Vascular Forum, Vol 47, Iss , Pp 97-100 (2020)
Introduction: Pneumatic weapons rarely cause severe trauma. However, pellet embolisation can cause severe and unexpected injuries. Report: This is the case study of a 32 year old man, who was shot in the chest with a pneumatic rifle. Initially, urgen
Externí odkaz:
https://doaj.org/article/67547a70562943678d0c261905184ec5
Autor:
Marcela Hortová-Kohoutková, Marco De Zuani, Petra Lázničková, Kamila Bendíčková, Ondřej Mrkva, Ivana Andrejčinová, Alexandra Mýtniková, Ondřej Polanský, Kamila Kočí, Veronika Tomášková, Vladimír Šrámek, Martin Helán, Jan Frič
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Sepsis and septic shock remain leading causes of morbidity and mortality for patients in the intensive care unit. During the early phase, immune cells produce various cytokines leading to prompt activation of the immune system. Polymorphonuclear leuk
Externí odkaz:
https://doaj.org/article/4f0c4bb5dd654f3797c88469645bd791