Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Martin Heinkelein"'
Publikováno v:
Journal of Virology. 79:7005-7013
Foamy viruses (FVs) generate their Pol protein precursor molecule independently of the Gag protein from a spliced mRNA. This mode of expression raises the question of the mechanism of Pol protein incorporation into the viral particle (capsid). We pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967f742475c451c99ee6eeb70771adbf
https://doi.org/10.1128/jvi.79.11.7005-7013.2005
https://doi.org/10.1128/jvi.79.11.7005-7013.2005
Autor:
Dirk Lindemann, Annett Stange, Marc Cartellieri, Heinrich G. Göttlinger, Ingrid Mannigel, Katrin Peters, Axel Rethwilm, Nicole Stanke, Martin Heinkelein, Hanswalter Zentgraf
Publikováno v:
Journal of Virology. 79:5466-5476
Foamy viruses (FV) are unusual among retroviruses since they require both Gag and Env structural proteins for particle egress. Recently significant progress has been made towards the mechanistic understanding of the viral release process, in particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8da3d36881cdb0725aa003f850dbe10
https://doi.org/10.1128/jvi.79.9.5466-5476.2005
https://doi.org/10.1128/jvi.79.9.5466-5476.2005
Autor:
Florian Kreppel, Axel Rethwilm, Stefan Kochanek, Thomas Juretzek, Ottmar Herchenröder, Martin Heinkelein, Marcus Picard-Maureau, Dirk Lindemann
Publikováno v:
Gene Therapy. 11:722-728
To confer adenovirus vectors (AdV), the feature of integration into the host cell genome hybrid vectors were characterized in vitro, which express vectors derived from the prototypic foamy virus (FV) in the backbone of a high-capacity AdV. FVs consti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7641bdfc996d2481761b65cfb51313
https://doi.org/10.1038/sj.gt.3302216
https://doi.org/10.1038/sj.gt.3302216
Publikováno v:
genesis. 39:94-99
Here we describe the efficient generation of eGFP-transgenic rats using a lentiviral approach. Analysis of the founder generation demonstrated that 46% of the offspring had stably integrated the provirus into the genome and of those 92% expressed eGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bdd728911ceb18fb8b3ee2e8f1d54f
https://doi.org/10.1002/gene.20037
https://doi.org/10.1002/gene.20037
Autor:
Axel Rethwilm, Ottmar Herchenröder, Martin Heinkelein, Dirk Lindemann, Michael Bock, Wolfram W. Rudolph, Thomas Juretzek, Jacqueline Roy, Kathleen Gärtner
Publikováno v:
Journal of Virology. 77:11324-11331
Crucial aspects of the foamy virus (FV) replication strategy have so far only been investigated for the prototypic FV (PFV) isolate, which is supposed to be derived from nonhuman primates. To study whether the unusual features of this replication pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c30ddf9bcb15daf1ffbeeb0423470d
https://doi.org/10.1128/jvi.77.21.11324-11331.2003
https://doi.org/10.1128/jvi.77.21.11324-11331.2003
Publikováno v:
Journal of Virology. 77:11855-11858
A remarkable feature of the prototype foamy virus (PFV) replication pathway has been reported to consist of the ability to retrotranspose intracellularly with high efficiency (M. Heinkelein, T. Pietschmann, G. Jármy, M. Dressler, H. Imrich, J. Thur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6abab0e2d0dc6c918f8216715498ca3e
https://doi.org/10.1128/jvi.77.21.11855-11858.2003
https://doi.org/10.1128/jvi.77.21.11855-11858.2003
Autor:
Dirk Lindemann, Martin Heinkelein, Matthias Rammling, Marco Dressler, Jana Thurow, H. Imrich, Axel Rethwilm, Gergely Jármy
Publikováno v:
Journal of Virology. 76:3774-3783
Foamy virus (FV) vectors that have minimal cis -acting sequences and are devoid of residual viral gene expression were constructed and analyzed by using a packaging system based on transient cotransfection of vector and different packaging plasmids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da88754471ec09cedc3d00a600df3e53
https://doi.org/10.1128/jvi.76.8.3774-3783.2002
https://doi.org/10.1128/jvi.76.8.3774-3783.2002
Autor:
Thomas Pietschmann, Martin Heinkelein, Hanswalter Zentgraf, Jana Thurow, Angelika Berg, Petra Knaus, Axel Rethwilm, Dirk Lindemann, Marcus Picard-Maureau
Publikováno v:
Journal of Virology. 75:5762-5771
Signal peptides (SP) are key determinants for targeting glycoproteins to the secretory pathway. Here we describe the involvement in particle maturation as an additional function of a viral glycoprotein SP. The SP of foamy virus (FV) envelope glycopro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20eaae5d1f40cc1d7b2a30bba6ced931
https://doi.org/10.1128/jvi.75.13.5762-5771.2001
https://doi.org/10.1128/jvi.75.13.5762-5771.2001
Publikováno v:
Journal of Medical Virology. 64:223-231
Conventional phenotypic analysis of resistance of the human immunodeficiency virus (HIV) to antiviral therapy is time-consuming and requires culture of infectious virus. Although phenotypic analyses may be desirable, rapid generation of test results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1c7e17061443681f000c906b0b9155b
https://doi.org/10.1002/jmv.1040
https://doi.org/10.1002/jmv.1040
Publikováno v:
Journal of General Virology. 81:2941-2947
Mouse monoclonal antibodies (MAbs) that specifically detect the 127 kDa Pol precursor and the 85 kDa reverse transcriptase/RNase H (RT/RN) or pr127 and the 40 kDa integrase (IN) in immunoblot and immunofluorescence assays (IFA) were used to investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea511e7e7cd1eeeb24c800b7b7fcd5f1
https://doi.org/10.1099/0022-1317-81-12-2941
https://doi.org/10.1099/0022-1317-81-12-2941