Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Martin Heidemann"'
Autor:
Nicolas Descostes, Martin Heidemann, Lionel Spinelli, Roland Schüller, Muhammad Ahmad Maqbool, Romain Fenouil, Frederic Koch, Charlène Innocenti, Marta Gut, Ivo Gut, Dirk Eick, Jean-Christophe Andrau
Publikováno v:
eLife, Vol 3 (2014)
In mammals, the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II consists of 52 conserved heptapeptide repeats containing the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Post-translational modifications of the CTD coordinate the tr
Externí odkaz:
https://doaj.org/article/56988b85933f4d25b9e33e45db564b68
Autor:
Jürgen Kann, Marc-Uwe Fischer, Margareta Häcker, Martin Heidemann, Michael Hendricks, Peter Hennke, Lars Hettich, Claudia Junker, Anjela Keiluweit, Dirk Langner, Michaela Matthes-Branscheid, Jan Thomas Petersen, Marcus Reischl, Stephan Zilles
Haftungsansprüche gegen Leitungsorgane sind mittlerweile keine Seltenheit - persönliche Haftungsrisiken können nur durch adäquates Vorstandshandeln vermieden werden. Vertiefte Kenntnisse der rechtlichen Regularien gehören daher zur Kernkompetenz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14c370b2c543104250acc96bafd4bf07
https://doi.org/10.37307/b.978-3-503-19580-0
https://doi.org/10.37307/b.978-3-503-19580-0
Autor:
Audrey P. Gasch, Gabriele Varani, Aseem Z. Ansari, Corinna Hintermair, Laurence Florens, Ying Zhang, Yi-Hsuan Ho, Dirk Eick, Corey M. Nemec, Sandra C. Tseng, Michael P. Washburn, Fan Yang, Joshua M. Gilmore, Martin Heidemann
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 114, E3944-E3953 (2017)
The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) orchestrates dynamic recruitment of specific cellular machines during different stages of transcription. Signature phosphorylation patterns of Y1S2P3T4S5P6S7 hept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02934fe7477873de43ba8b2171e29d2
https://pubmed.ncbi.nlm.nih.gov/28465432
https://pubmed.ncbi.nlm.nih.gov/28465432
Autor:
Katja Strässer, Kaspar Burger, Michaela Rohrmoser, Anita Gruber-Eber, Markus Kellner, Bastian Mühl, Dirk Eick, Vigo Heissmeyer, Martin Heidemann, Britta Coordes
Publikováno v:
Journal of Biological Chemistry
J. Biol. Chem. 288, 21173-21183 (2013)
J. Biol. Chem. 288, 21173-21183 (2013)
Ribosome biogenesis is a process required for cellular growth and proliferation. Processing of ribosomal RNA (rRNA) is highly sensitive to flavopiridol, a specific inhibitor of cyclin-dependent kinase 9 (Cdk9). Cdk9 has been characterized as the cata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b736c54b4dd2545b45b848b3eb277f6
https://doi.org/10.1074/jbc.m113.483719
https://doi.org/10.1074/jbc.m113.483719
Autor:
Ignasi Forné, Corinna Hintermair, Martin Heidemann, Elisabeth Kremmer, Andrew Flatley, Dirk Eick, Axel Imhof, Kirsten Voß
Publikováno v:
Sci. Rep. 6:27401 (2016)
Scientific Reports
Scientific Reports
Dynamic phosphorylation of Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7 heptad-repeats in the C-terminal domain (CTD) of the large subunit coordinates progression of RNA polymerase (Pol) II through the transcription cycle. Here, we describe an M phase-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0548a63266d23789f57e6daae48190a3
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=48765
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=48765
Autor:
Corinna Hintermair, Nicolas Descostes, Ivo Gut, Frederic Koch, Rob D. Chapman, Marta Gut, Jean-Christophe Andrau, Elisabeth Kremmer, Andrew Flatley, Dirk Eick, Romain Fenouil, Martin Heidemann, Pierre Ferrier
Publikováno v:
The EMBO Journal. 31:2784-2797
Eukaryotic RNA polymerase II (Pol II) has evolved an array of heptad repeats with the consensus sequence Tyr1‐Ser2‐Pro3‐Thr4‐Ser5‐Pro6‐Ser7 at the carboxy‐terminal domain (CTD) of the large subunit (Rpb1). Differential phosphorylation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca886058eaea627d68559321bf43725
https://doi.org/10.1038/emboj.2012.123
https://doi.org/10.1038/emboj.2012.123
Publikováno v:
BIOspektrum. 17:270-273
Die C-terminale Domane (CTD) der RNA-Polymerase II (RNAPII) ermoglicht die Transkription von Chromatin, koordiniert viele RNA-Reifungsschritte und ist wichtig fur das Lesen und Schreiben epigenetischer Information.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27373f552ea9f55060e708e12370adeb
https://doi.org/10.1007/s12268-011-0040-4
https://doi.org/10.1007/s12268-011-0040-4
Autor:
Juan B. Rodríguez-Molina, Brent E. White, Sohail Akhtar, David W. Zhang, Kevan M. Shokat, Aseem Z. Ansari, Xin Li, Rob D. Chapman, Joshua R. Tietjen, Sunduz Keles, Martin Heidemann, Dirk Eick
Publikováno v:
Nature structural & molecular biology
Nature structural & molecular biology, vol 17, iss 9
Nature structural & molecular biology, vol 17, iss 9
Summary Sequential modifications of the RNA polymerase II (Pol II) carboxyl-terminal domain (CTD) coordinate the stage-specific association and release of cellular machines during transcription. Here we examine the genome-wide distributions of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080893a1626573dc494d02b3d9bf6ce1
http://europepmc.org/articles/PMC4035229
http://europepmc.org/articles/PMC4035229
Publikováno v:
Trends in Genetics. 24:289-296
In higher eukaryotes, an unusual C-terminal domain (CTD) is crucial to the function of RNA polymerase II in transcription. The CTD consists of multiple heptapeptide repeats; differences in the number of repeats between organisms and their degree of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54109f063ace5aa97ccf1cf605ee207b
https://doi.org/10.1016/j.tig.2008.03.010
https://doi.org/10.1016/j.tig.2008.03.010
Autor:
Corinna Hintermair, Marta Gut, Jean-Christophe Andrau, Nicolas Descostes, Axel Imhof, Muhammad Ahmad Maqbool, Elisabeth Kremmer, Martin Heidemann, Ignasi Forné, Kirsten Voss, Roland Schüller, Ivo Gut, Andrew Flatley, Dirk Eick
Publikováno v:
Transcription
Dynamic modification of heptad-repeats with the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7 of RNA polymerase II (RNAPII) C-terminal domain (CTD) regulates transcription-coupled processes. Mass spectrometry analysis revealed that K7-residue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04dd6b055b63300411c107494da7a752
https://pubmed.ncbi.nlm.nih.gov/26566685
https://pubmed.ncbi.nlm.nih.gov/26566685