Výsledky vyhledávání - "Martin Hauses"

Physical and functional characterization of the human LGI1 gene and its possible role in glioma development

Autor: Gerhard Ehninger, Dietmar Krex, Martin Hauses, Gabriele Schackert, Hella Appelt, Hans Konrad Schackert, Brigitte Mohr

Publikováno v: Acta Neuropathologica. 103:255-266

The human gene termed LGI1 (leucine-rich gene - glioma inactivated) has been isolated recently, and is supposed to be an additional candidate tumor suppressor gene involved in the formation and progression of glioblastoma multiforme [Chernova et al.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a5569bf8304164ff0887ae92d5f2f1
https://doi.org/10.1007/s004010100463

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[Untitled]

Autor: Gerhard Ehninger, Dietmar Krex, Brigitte Mohr, Hans K. Schackert, Martin Hauses, Gabriele Schackert

Publikováno v: Journal of Neuro-Oncology. 52:119-128

To elucidate the reasons why mRNA expression of the LGI1 candidate tumor-suppressor gene was severely reduced in the glioma-derived cell line H4, as demonstrated in a previous study, we performed a cytogenetic analysis of this cell line using convent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87c8dabfbcc21065827b2b9c2faf1f14
https://doi.org/10.1023/a:1010680920087

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The Transcription Factor Sp1 Regulates the Myeloid-specific Expression of the Human Hematopoietic Cell Kinase (HCK) Gene through Binding to Two Adjacent GC Boxes within the HCK Promoter-Proximal Region

Autor: Ralf R. Tönjes, Manuel Grez, Martin Hauses

Publikováno v: Journal of Biological Chemistry. 273:31844-31852

The human hemopoietic cell kinase (HCK) is a member of the src family of protein tyrosine kinases specifically expressed in myeloid cells and to a minor extent in B-lymphoid cells. HCK expression is up-regulated at the transcriptional level during my

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ed3f4a888828a1142576eb9149d325
https://doi.org/10.1074/jbc.273.48.31844

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Synthesis and preliminary evaluation of N1-methyl-9-[(1-hydroxy-3-[18F]fluoro-2-propoxy)methyl]guanine [18F]MFHPG, a new substrate of HSV-1-thymidine kinase

Autor: Matthias Scheunemann, Bernhard Noll, St. Noll, Hans K. Schackert, Peter Brust, M. Grote, Martin Hauses, Bernd Johannsen, A. Friedrich

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 44:S439-S441

The labelling procedure for N1-methyl-9-[(1-hydroxy-3-[18F]fluoro-2-propoxy)methyl]guanine ([18F]MFHPG), a novel substrate of HSV1-TK that possess potent properties to image the gene expression, and its preliminary biodistribution in rats are reporte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9672fd81a307fb5007420f55402989dc
https://doi.org/10.1002/jlcr.25804401155

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In vivo studies on the availability and toxicity of antisense oligonucleotides in bladder cancer

Autor: Caroline E, Blietz, Beate, Thode, Martin, Hauses, Ralph, Pries, Alexander J, Meyer, Christian, Doehn, Dieter, Jocham, Ingo, Kausch

Publikováno v: In vivo (Athens, Greece). 23(1)

The urinary bladder is an ideal organ for topical treatment. A substantial number of bladder cancer patients are resistant to conventional intravesical therapy. In search of new agents, antisense oligonucleotides (AS-ON) may be interesting candidates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8d0290ad254e27dc3a6bb5ff74a7d76
https://pubmed.ncbi.nlm.nih.gov/19368119

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Loss of expression of ZAC/LOT1 in squamous cell carcinomas of head and neck

Autor: Susanne Koy, Hella Appelt, Katrin Friedrich, Hans K. Schackert, Martin Hauses, Uwe Eckelt

Publikováno v: Headneck. 26(4)

Background. ZAC/Lot1 is a previously identified candidate tumor suppressor gene. The gene maps to the human chromosome 6q24-q25, a region frequently deleted in squamous cell carcinomas of the head and neck and other solid tumors. Methods. We have use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d30f6c83f935b096dc3eeaf0301480
https://pubmed.ncbi.nlm.nih.gov/15054737

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Comparison of [18F]FHPG and [124/125I]FIAU for imaging herpes simplex virus type 1 thymidine kinase gene expression

Autor: Steffi Noll, Hans K. Schackert, Bernd Johannsen, Norbert Avril, Roland Haubner, Peter Brust, Anne Friedrich, Uwe Haberkorn, Martina Anton, Olga Niki Koufaki, Bernhard Noll, Matthias Scheunemann, Martin Hauses, Gabriele Schackert

Publikováno v: European journal of nuclear medicine. 28(6)

Various radiotracers based on uracil nucleosides (e.g. [124I]2'-fluoro-2'-deoxy-5-iodo-1-beta-D-arabinofuranosyluracil, [124I]FIAU) and acycloguanosine derivatives (e.g. [18F]9-[(3-fluoro-1-hydroxy-2-propoxy) methyl] guanine, [18F]FHPG) have been pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c317d549870014792ca48928648cd2
https://pubmed.ncbi.nlm.nih.gov/11440032

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Correction of respiratory burst activity in X-linked chronic granulomatous cells to therapeutically relevant levels after gene transfer into bone marrow CD34+ cells

Autor: Arnold Ganser, Reinhard Seger, Johann Peter Hossle, Mary C. Dinauer, Sandra Wasser, Manuel Grez, Martin Hauses, Marion Ott, Sven Becker, Dieter Hoelzer

Publikováno v: Human gene therapy. 9(11)

Chronic granulomatous disease (CGD) is a disorder of the lymphohematopoietic system, whereby phagocytes of affected patients are unable to kill microorganisms. CGD is caused by a functional defect in the phagocytic nicotinamide adenine dinucleotide p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca14e6ecb22f4db0436829d2c62e6391
https://pubmed.ncbi.nlm.nih.gov/9694155

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