Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Martin Haupt-Jorgensen"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/ce5a5236ccc847ef8370544e5f165c8c
Autor:
Camilla Hartmann Friis Hansen, Martin Haupt‐Jorgensen, Karsten Buschard, Bente Pakkenberg, Lukasz Krych, Axel Kornerup Hansen
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 2, Pp n/a-n/a (2023)
Abstract Background Early antibiotic treatment changes susceptibility to disease in rodent models for type 1 diabetes, but the impact that gestational antibiotics may have on pancreatic embryogenesis and β cell function later in life is still unknow
Externí odkaz:
https://doaj.org/article/863784c01dfa40cab2ace2c2a46937e8
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0289258 (2023)
Type 1 diabetes (T1D) is an autoimmune disease with an unexplained rising incidence for which environmental factors like gluten may play a role. Previously, we showed that a gluten-free (GF) diet provided strictly in utero reduces the autoimmune diab
Externí odkaz:
https://doaj.org/article/6cb5e19fa9f14523bb2474d7ccf21b14
Autor:
Valdemar Brimnes Ingemann Johansen, Daisy Færø, Karsten Buschard, Karsten Kristiansen, Flemming Pociot, Pia Kiilerich, Knud Josefsen, Martin Haupt-Jorgensen, Julie Christine Antvorskov
Publikováno v:
Cells, Vol 12, Iss 12, p 1567 (2023)
The incidence of the autoimmune disease type 1 diabetes is increasing, likely caused by environmental factors. A gluten-free diet has previously been shown to ameliorate autoimmune diabetes in non-obese diabetic (NOD) mice and humans. Although the ex
Externí odkaz:
https://doaj.org/article/b2c42a13b2a945fd8645ea5dbb6b5f17
Publikováno v:
PPAR Research, Vol 2020 (2020)
Peroxisome proliferator-activated receptors (PPARs) are a family of transcription factors with a key role in glucose and lipid metabolism. PPARs are expressed in many cell types including pancreatic beta cells and immune cells, where they regulate in
Externí odkaz:
https://doaj.org/article/16f73e277629494fbe289350cac7392e
Autor:
Laurits J Holm, Martin Haupt-Jorgensen, Jesper Larsen, Jano D Giacobini, Mesut Bilgin, Karsten Buschard
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194414 (2018)
Sphingolipids are a diverse group of lipids with important roles in beta-cell biology regulating insulin folding and controlling apoptosis. Sphingolipid biosynthesis begins with the condensation of L-serine and palmitoyl-CoA. Here we tested the effec
Externí odkaz:
https://doaj.org/article/bc6b7c684378410db0b95b3b96ab786f
Autor:
Martin Haupt-Jorgensen, Erik Nielsen, Kåre Engkilde, Mia Lerche, Jesper Larsen, Karsten Buschard
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181143 (2017)
Intranasal administration of gliadin prevents autoimmune diabetes in non-obese diabetic mice. The current study was designed to investigate if bakers are intranasally exposed to gluten during work and whether occupation as baker is inversely associat
Externí odkaz:
https://doaj.org/article/fb0098fb38bd41608ae65ea5784f1304
Autor:
Susanne W. Bruun, Knud Josefsen, Julia T. Tanassi, Aleš Marek, Martin H. F. Pedersen, Ulrik Sidenius, Martin Haupt-Jorgensen, Julie C. Antvorskov, Jesper Larsen, Niels H. Heegaard, Karsten Buschard
Publikováno v:
Journal of Diabetes Research, Vol 2017 (2017)
Externí odkaz:
https://doaj.org/article/4535a2be384d4135a48b444df02c53c5
Autor:
Julie C. Antvorskov, Knud Josefsen, Martin Haupt-Jorgensen, Petra Fundova, David P. Funda, Karsten Buschard
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Studies have documented that the pathogenesis of autoimmune diabetes is influenced by the intake of gluten. Aims. To investigate the importance of gluten exposure during pregnancy and the subsequent development of autoimmune diabetes in offspring. Me
Externí odkaz:
https://doaj.org/article/5b9e4ded7d25465e9d6775ed63e3f0ac
Autor:
Susanne W. Bruun, Knud Josefsen, Julia T. Tanassi, Aleš Marek, Martin H. F. Pedersen, Ulrik Sidenius, Martin Haupt-Jorgensen, Julie C. Antvorskov, Jesper Larsen, Niels H. Heegaard, Karsten Buschard
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Gluten promotes type 1 diabetes in nonobese diabetic (NOD) mice and likely also in humans. In NOD mice and in non-diabetes-prone mice, it induces inflammation in the pancreatic lymph nodes, suggesting that gluten can initiate inflammation locally. Fu
Externí odkaz:
https://doaj.org/article/fe19ad5d509b49ac928332016b8b7943