Editorial: The gut-pancreas axis in type 1 diabetes – a focus on environmental factors

Autor: Tina Fløyel, David Funda, Veronica I. Dodero, Martin Haupt-Jorgensen

Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)

Externí odkaz: https://doaj.org/article/ce5a5236ccc847ef8370544e5f165c8c

Failure to replicate the diabetes alleviating effect of a maternal gluten-free diet in non-obese diabetic mice.

Autor: Mia Øgaard Mønsted, Laurits Juulskov Holm, Karsten Buschard, Martin Haupt-Jorgensen

Publikováno v: PLoS ONE, Vol 18, Iss 9, p e0289258 (2023)

Type 1 diabetes (T1D) is an autoimmune disease with an unexplained rising incidence for which environmental factors like gluten may play a role. Previously, we showed that a gluten-free (GF) diet provided strictly in utero reduces the autoimmune diab

Externí odkaz: https://doaj.org/article/6cb5e19fa9f14523bb2474d7ccf21b14

Reduced phosphatidylcholine level in the intestinal mucus layer of prediabetic NOD mice

Autor: Mia Øgaard Mønsted, Mesut Bilgin, Marek Kuzma, Helena Pelantová, Kristina Pedersen, Petra Tomášová, Anastasiia Nazmutdinova, Blanka Šedivá, David Funda, Josué L. Castro‐Mejía, Laurits Juulskov Holm, Dennis Sandris Nielsen, Martin Haupt‐Jorgensen

Publikováno v: Mønsted, M Ø, Bilgin, M, Kuzma, M, Pelantová, H, Pedersen, K, Tomášová, P, Nazmutdinova, A, Šedivá, B, Funda, D, Castro-Mejía, J L, Holm, L J, Nielsen, D S & Haupt-Jorgensen, M 2023, ' Reduced phosphatidylcholine level in the intestinal mucus layer of prediabetic NOD mice ', APMIS-Journal of Pathology, Microbiology and Immunology, vol. 131, no. 6, pp. 237-248 . https://doi.org/10.1111/apm.13302

Type 1 diabetes (T1D) is an autoimmune disease with rising incidence. Pre- and manifest T1D is associated with intestinal barrier dysfunction, skewed microbiota composition, and serum dyslipidemia. The intestinal mucus layer protects against pathogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa299c76aa546cf3f5dc26192adf6cb4
https://doi.org/10.1111/apm.13302

A Gluten-Free Diet during Pregnancy and Early Life Increases Short Chain Fatty Acid-Producing Bacteria and Regulatory T Cells in Prediabetic NOD Mice

Autor: Antvorskov, Valdemar Brimnes Ingemann Johansen, Daisy Færø, Karsten Buschard, Karsten Kristiansen, Flemming Pociot, Pia Kiilerich, Knud Josefsen, Martin Haupt-Jorgensen, Julie Christine

Publikováno v: Cells; Volume 12; Issue 12; Pages: 1567

The incidence of the autoimmune disease type 1 diabetes is increasing, likely caused by environmental factors. A gluten-free diet has previously been shown to ameliorate autoimmune diabetes in non-obese diabetic (NOD) mice and humans. Although the ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::73685b54de14f0dbd3c804b779bc2f64

Occupation with grain crops is associated with lower type 1 diabetes incidence: Registry-based case-control study.

Autor: Martin Haupt-Jorgensen, Erik Nielsen, Kåre Engkilde, Mia Lerche, Jesper Larsen, Karsten Buschard

Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0181143 (2017)

Intranasal administration of gliadin prevents autoimmune diabetes in non-obese diabetic mice. The current study was designed to investigate if bakers are intranasally exposed to gluten during work and whether occupation as baker is inversely associat

Externí odkaz: https://doaj.org/article/fb0098fb38bd41608ae65ea5784f1304