Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Martin H. Kunzmann"'
Autor:
Martin H. Kunzmann, Stephan A. Sieber, Thomas Böttcher, Joanna Krysiak, Oliver Baron, Franziska Weinandy, Jan Vomacka, Katrin Lorenz-Baath, Vadim S. Korotkov, Bianca Bauer
Publikováno v:
Chemistry - A European Journal. 22:1622-1630
Methicillin-resistant Staphylococcus aureus (MRSA) causes severe infections with only few effective antibiotic therapies currently available. To approach this challenge, chemical entities with a novel and resistance-free mode of action are desperatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4288a364dbbb1f6a125edea8b174ba35
https://doi.org/10.1002/chem.201503981
https://doi.org/10.1002/chem.201503981
Publikováno v:
Biochemistry. 50:910-916
The discovery of novel and unique target-drug pairs for the treatment of human diseases such as cancer and bacterial infections is an urgent goal of chemical and pharmaceutical sciences. Natural products represent an inspiring source of compounds for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854aa4216c83044163c701cfdcce343c
https://doi.org/10.1021/bi101858g
https://doi.org/10.1021/bi101858g
Publikováno v:
Chemical Science. 5:1158
Bacterial pathogenesis is triggered by complex molecular mechanisms that sense bacterial density within an infected host and induce the expression of toxins for overriding the immune response. Virulence is controlled by a set of transcriptional regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78bde564ffbc7351f2ca6f3abe89c901
https://doi.org/10.1039/c3sc52228h
https://doi.org/10.1039/c3sc52228h
Autor:
Martin H. Kunzmann, Stephan A. Sieber
Publikováno v:
Molecular BioSystems. 8:3061
α-Alkylidene-γ-butyrolactones are quite common in nature and exhibit a broad spectrum of biological activities. We therefore synthesized a small library of xanthatine inspired α-alkylidene-γ-butyrolactones to screen non-pathogenic and uropathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fb4e50af13120b0c34f35d4d7745d2
https://doi.org/10.1039/c2mb25313e
https://doi.org/10.1039/c2mb25313e