Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Martin H. Hoffer"'
Autor:
Vjera Grabovac, Martin H. Hoffer, Andreas Bernkop-Schnürch, Thomas F. Palmberger, Thierry Schmitz
Publikováno v:
International Journal of Pharmaceutics. 347:79-85
The aim of the present study was to synthesize and characterize a novel thiolated polymer by covalent attachment of N-acetyl cysteine to chitosan. The obtained conjugate was characterized in vitro by quantification of immobilized thiol groups and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5265e8f3841f48f2619bfb8fdbb2ad
https://doi.org/10.1016/j.ijpharm.2007.06.040
https://doi.org/10.1016/j.ijpharm.2007.06.040
Autor:
Martin Werle, Martin H. Hoffer, Krum Kafedjiiski, Ram K. R. Jetti, Andreas Bernkop-Schnürch, Florian Föger, Herbert Hoyer
Publikováno v:
International Journal of Pharmaceutics. 343:48-58
It was the aim of this study to synthesize and characterize a novel hyaluronic acid-cysteine ethyl ester (HA-Cys) conjugate providing improved mucoadhesive properties and a significantly lowered biodegradation rate. Mediated by carbodiimide and N-hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f3cc920c9c47a8a8ba7d9d7b166097
https://doi.org/10.1016/j.ijpharm.2007.04.019
https://doi.org/10.1016/j.ijpharm.2007.04.019
Publikováno v:
Biomaterials. 26:819-826
In order to achieve the same properties as chitosan-4-thio-butyl-amidine and to overcome at the same time its insufficient stability, the aim of this study was to evaluate the imidoester reaction of isopropyl-S-acetylthioacetimidate for the chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5b8b242d409c6d4b93f8eac9fcfb30
https://doi.org/10.1016/j.biomaterials.2004.03.011
https://doi.org/10.1016/j.biomaterials.2004.03.011
Publikováno v:
Drug Development and Industrial Pharmacy. 31:885-893
The aim of this study was the synthesis of a new thiolated chitosan conjugate and the evaluation of its viscoelastic properties in vitro. The modification of chitosan was achieved by covalent attachment of isopropyl-S-acetylthioacetimidate to chitosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8717622264e6ddfaae4c425d152e7f24
https://doi.org/10.1080/03639040500271985
https://doi.org/10.1080/03639040500271985
Publikováno v:
International Journal of Pharmaceutics. 278:353-360
d -Glucosamine and chitosan were modified by the immobilization of thiol groups utilizing 2-iminothiolane. The toxicity profile of the resulting d -glucosamine-TBA (4-thiobutylamidine) conjugate, of chitosan-TBA conjugate and of the corresponding unm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722a547465b6e32f5f9ea4c5266ba43e
https://doi.org/10.1016/j.ijpharm.2004.03.016
https://doi.org/10.1016/j.ijpharm.2004.03.016
Autor:
Martin H. Hoffer, Martin Werle
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 111(1-2)
The aim of the present study was to evaluate the influence of glutathione (GSH), the thiomer chitosan-4-thiobutylamidine (chitosan-TBA) and a combination of both compounds on P-glycoprotein (P-gp) activity. Permeation studies were performed with fres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1d8e175f9e3b4abe48224bdb5024ff
https://pubmed.ncbi.nlm.nih.gov/16377016
https://pubmed.ncbi.nlm.nih.gov/16377016
Publikováno v:
Biomaterials. 27(1)
The aim of this study was to establish improved reaction conditions for the synthesis of chitosan–thioethylamidine (Ch-TEA) conjugate and to evaluate the properties of the obtained Ch-TEA conjugate. The influence of different factors on the couplin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba048a738c20b876dd42606c7eab34f
https://pubmed.ncbi.nlm.nih.gov/16045983
https://pubmed.ncbi.nlm.nih.gov/16045983
Autor:
Krauland, Alexander H.1 (AUTHOR), Hoffer, Martin H.2 (AUTHOR), Bernkop-Schnürch, Andreas1,3 (AUTHOR) andreas.bernkop@uibk.ac.at
Publikováno v:
Drug Development & Industrial Pharmacy. Oct2005, Vol. 31 Issue 9, p885-893. 9p.
Selected, peer reviewed papers from the 3rd international Conference on Manufacturing Science and Engineering (ICMSE 2012), March 27-29, 2012, Xiamen, China
