Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Martin Guillot"'
Autor:
Vincent A. Stadelmann, Gabrielle Boyd, Martin Guillot, Jean-Guy Bienvenu, Charles Glaus, Aurore Varela
Publikováno v:
International Journal of Biomedical Imaging, Vol 2021 (2021)
Objective. While microCT evaluation of atherosclerotic lesions in mice has been formally validated, existing image processing methods remain undisclosed. We aimed to develop and validate a reproducible image processing workflow based on phosphotungst
Externí odkaz:
https://doaj.org/article/de3c6ee816b44f3bbfc576a3d40cfb50
Publikováno v:
Animals, Vol 5, Iss 4, Pp 1252-1267 (2015)
Subtle signs and conflicting physical and radiographic findings make feline osteoarthritis (OA) challenging to diagnose. A physical examination-based assessment was developed, consisting of eight items: Interaction, Exploration, Posture, Gait, Body C
Externí odkaz:
https://doaj.org/article/6dee2c626ab64ee9bc119b186766885d
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169745 (2017)
Adrenaline is known to prolong the duration of local anesthesia but its effects on the pharmacokinetic processes of local anesthetic drugs are not fully understood. Our objective was to develop a compartmental model for quantification of adrenaline's
Externí odkaz:
https://doaj.org/article/62a27cc1817d4c94a08f138c4211617e
Autor:
Beatriz P Monteiro, Mary P Klinck, Maxim Moreau, Martin Guillot, Paulo V M Steagall, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Dominique Gauvin, Jérôme R E Del Castillo, Eric Troncy
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175565 (2017)
This study aimed to (1) compare outcome assessments in normal and osteoarthritic cats and (2) evaluate the analgesic efficacy of tramadol in feline osteoarthritis (OA), in a prospective, randomised, blinded, placebo-controlled, crossover design.Twent
Externí odkaz:
https://doaj.org/article/00549db9b0714530a5a3af4745e43636
Autor:
Martin Guillot, Polly M Taylor, Pascale Rialland, Mary P Klinck, M Maxim Moreau, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Eric Troncy
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97347 (2014)
In cats, osteoarthritis causes significant chronic pain. Chronicity of pain is associated with changes in the central nervous system related to central sensitization, which have to be quantified. Our objectives were 1) to develop a quantitative senso
Externí odkaz:
https://doaj.org/article/bb4af540fa404750ad407f6882771200
Autor:
Pascale Rialland, Simon Authier, Martin Guillot, Jérôme R E Del Castillo, Daphnée Veilleux-Lemieux, Diane Frank, Dominique Gauvin, Eric Troncy
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49480 (2012)
In the context of translational research, there is growing interest in studying surgical orthopedic pain management approaches that are common to humans and dogs. The validity of postoperative pain assessment methods is uncertain with regards to resp
Externí odkaz:
https://doaj.org/article/93f08a9f9e1c4cc7bc71c0cdfaed4b9b
Autor:
Sokhna Keita-Alassane, Colombe Otis, Emilie Bouet, Martin Guillot, Marilyn Frezier, Aliénor Delsart, Maxim Moreau, Agathe Bédard, Isabelle Gaumond, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Francis Beaudry, Bertrand Lussier, Roger Lecomte, Serge Marchand, Eric Troncy
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 395:703-715
Several observational studies suggest that estrogens could bias pain perception. To evaluate the influence of estrogenic impregnation on pain expression, a prospective, randomized, controlled, blinded study was conducted in a Sprague-Dawley rat model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e6a580c8fe7c6fff24b4f69b6daedd
https://doi.org/10.1007/s00210-022-02231-5
https://doi.org/10.1007/s00210-022-02231-5
Autor:
Jeffrey L. Brown, Aurore Varela, Bruce H. Mitlak, Marilyne Boyer, Paul J. Kostenuik, Allen Pierce, Martin Guillot, Beate Lanske, Heidi Chandler, Gary Hattersley, Roland Baron, Michael S. Ominsky
Publikováno v:
Bone. 120:148-155
Male osteoporosis can occur with advanced age and with hypogonadism, with increased bone resorption and/or inadequate bone formation contributing to reduced bone mass and increased fracture risk. Abaloparatide is a selective PTH receptor agonist that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30eae52e4b8ae8c7bb3e2eb5763d8f88
https://doi.org/10.1016/j.bone.2018.10.012
https://doi.org/10.1016/j.bone.2018.10.012
Autor:
M. Krautmann, J. Messamore, P. Cole, L.M. Bergeron, Rai Sharath K, K. Saad, J. Tena, Martin Guillot, L. Chouinard, Duncan Mwangi, Paul J. Dominowski, R. Walters, Y. Zhu
Publikováno v:
Veterinary journal (London, England : 1997). 276
Nerve growth factor (NGF), a critical mediator of nociception, is a novel analgesic therapeutic target. Bedinvetmab, a canine monoclonal antibody (mAb), binds NGF and inhibits its interaction with tropomyosin receptor kinase A (trkA) and p75 neurotro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518be3f91979de319411bf4a87ef7ecd
https://pubmed.ncbi.nlm.nih.gov/34391918
https://pubmed.ncbi.nlm.nih.gov/34391918
Autor:
Alison Wolfreys, Marina Stolina, Aimee M. Deaton, Sheetal V. Kumar, Jun Yin, Gabrielle Boyd, James R. Turk, Charles Glaus, Emily M. de Koning, Lucas D. Ward, Aurore Varela, Yusheng Qu, Gill Holdsworth, Jean-Guy Bienvenu, Yudong D. He, Martin Guillot, Melanie Felx, Denise Dwyer, Michael J. Engwall, Rogely W. Boyce, Kathrin Locher
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 115
Romosozumab (EVENITY™ [romosozumab-aqqg in the US]) is a humanized monoclonal antibody that inhibits sclerostin and has been approved in several countries for the treatment of osteoporosis in postmenopausal women at high risk of fracture. Sclerosti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869719aab28883f3928edc99a9d7aba0
https://pubmed.ncbi.nlm.nih.gov/32590049
https://pubmed.ncbi.nlm.nih.gov/32590049