Zobrazeno 1 - 10
of 323
pro vyhledávání: '"Martin Götte"'
Autor:
Maram Hilwi, Katherina Shulman, Inna Naroditsky, Sari Feld, Miriam Gross-Cohen, Ilanit Boyango, Soaad Soboh, Olga Vornicova, Malik Farhoud, Preeti Singh, Gil Bar-Sela, Hadassah Goldberg, Martin Götte, Andrew D. Sharrocks, Yaoyong Li, Ralph D. Sanderson, Neta Ilan, Israel Vlodavsky
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-13 (2024)
Abstract Unlike the intense research effort devoted to exploring the significance of heparanase in cancer, very little attention was given to Hpa2, a close homolog of heparanase. Here, we explored the role of Hpa2 in breast cancer. Unexpectedly, we f
Externí odkaz:
https://doaj.org/article/09ad1fee324e44e58f2c01dcb813d1a6
Autor:
Lidia A. Mielke Cabello, Gabriela Meresman, Dogus Darici, Noelia Carnovale, Birthe Heitkötter, Miriam Schulte, Nancy A. Espinoza-Sánchez, Quang-Khoi Le, Ludwig Kiesel, Sebastian D. Schäfer, Martin Götte
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 876 (2024)
Ferroptosis, an iron-dependent form of non-apoptotic cell death, plays a pivotal role in various diseases and is gaining considerable attention in the realm of endometriosis. Considering the classical pathomechanism theories, we hypothesized that fer
Externí odkaz:
https://doaj.org/article/304106cd3d0c40af8069a27a2180ef60
Autor:
Mark Sicking, Isabel Falke, Maria T. Löblein, Hans Th. Eich, Martin Götte, Burkhard Greve, Fabian M. Troschel
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract RNA-binding proteins have increasingly been identified as important regulators of gene expression given their ability to bind distinct RNA sequences and regulate their fate. Mounting evidence suggests that RNA-binding proteins are involved i
Externí odkaz:
https://doaj.org/article/767148948ad44e53ad0abf98308c1efd
Autor:
Marina Sourouni, Carl Opitz, Isabel Radke, Ludwig Kiesel, Joke Tio, Martin Götte, Marie‐Kristin vonWahlde
Publikováno v:
Cancer Reports, Vol 6, Iss 4, Pp n/a-n/a (2023)
Abstract Background Ductal carcinoma in situ (DCIS) is a precursor form of breast cancer. 13%–50% of these lesions will progress to invasive breast cancer, but the individual progression risk cannot be estimated. Therefore, all patients receive the
Externí odkaz:
https://doaj.org/article/3706ad351d6347d68eb0123ab93790b7
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/4903dd7fa2e64106a507bbd624632c18
Autor:
Isabel Falke, Fabian M. Troschel, Heike Palenta, Maria T. Löblein, Kathrin Brüggemann, Katrin Borrmann, Hans Theodor Eich, Martin Götte, Burkhard Greve
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Endometrial carcinoma is the most common gynecological cancer in Europe. Musashi-1 is known to be a key regulator of endometrial cancer stem cells and a negative prognostic marker. In the present study, we aimed to understand grow
Externí odkaz:
https://doaj.org/article/2a9460a3e46b4df8b17448f2d9554235
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/a4f63d87efaa481da6dae2c3a788ade0
Autor:
Nourhan Hassan, Nico Bückreiß, Janes Efing, Marie Schulz-Fincke, Philipp König, Burkhard Greve, Gerd Bendas, Martin Götte
Publikováno v:
Cells, Vol 12, Iss 6, p 910 (2023)
Syndecan-1 (Sdc-1) upregulation is associated with poor prognosis in breast cancer. Sdc-1 knockdown results in reduced angiogenesis and the dysregulation of tissue factor (TF) pathway constituents. Here, we evaluate the regulatory mechanisms and func
Externí odkaz:
https://doaj.org/article/dcd1ba93aa3845a7ac7ca753d5f42768
Autor:
Anna Stejskalová, Victoria Fincke, Melissa Nowak, Yvonne Schmidt, Katrin Borrmann, Marie-Kristin von Wahlde, Sebastian D. Schäfer, Ludwig Kiesel, Burkhard Greve, Martin Götte
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Endometriosis is a painful gynecological condition characterized by ectopic growth of endometrial cells. Little is known about its pathogenesis, which is partially due to a lack of suitable experimental models. Here, we use endometrial strom
Externí odkaz:
https://doaj.org/article/b8b9f85f6a7e4d00ad06a95a5e0ba396
Autor:
Melanie Timmen, Heriburg Hidding, Martin Götte, Thaqif El Khassawna, Daniel Kronenberg, Richard Stange
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract The heparan sulfate proteoglycan Syndecan-1, a mediator of signals between the extracellular matrix and cells involved is able to interact with OPG, one of the major regulators of osteoclastogenesis. The potential of osteoblasts to induce os
Externí odkaz:
https://doaj.org/article/9a6ee4e2f41b4963b385a2e72b22d6ad