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pro vyhledávání: '"Martin Geroldinger"'
Autor:
Martin Geroldinger, Johan Verbeeck, Andrew C. Hooker, Konstantin E. Thiel, Geert Molenberghs, Joakim Nyberg, Johann Bauer, Martin Laimer, Verena Wally, Arne C. Bathke, Georg Zimmermann
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Background Recommendations for statistical methods in rare disease trials are scarce, especially for cross-over designs. As a result various state-of-the-art methodologies were compared as neutrally as possible using an illustrative data set
Externí odkaz:
https://doaj.org/article/4f9b12e7fc3f4ae699a506a509e41b49
Autor:
Martin Geroldinger, Johan Verbeeck, Konstantin E. Thiel, Geert Molenberghs, Arne C. Bathke, Martin Laimer, Georg Zimmermann
Publikováno v:
Biometrical Journal.
Ordinal data in a repeated measures design of a crossover study for rare diseases usually do not allow for the use of standard parametric methods, and hence, nonparametric methods should be considered instead. However, only limited simulation studies