Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Martin Gauster"'
Autor:
Beatrice Anna Brugger, Lena Neuper, Jacqueline Guettler, Désirée Forstner, Stefan Wernitznig, Daniel Kummer, Freya Lyssy, Julia Feichtinger, Julian Krappinger, Amin El-Heliebi, Lilli Bonstingl, Gerit Moser, Giovanny Rodriguez-Blanco, Olaf A. Bachkönig, Benjamin Gottschalk, Michael Gruber, Olivia Nonn, Florian Herse, Stefan Verlohren, Hans-Georg Frank, Nirav Barapatre, Cornelia Kampfer, Herbert Fluhr, Gernot Desoye, Martin Gauster
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-21 (2023)
Abstract Background The human placenta, a tissue with a lifespan limited to the period of pregnancy, is exposed to varying shear rates by maternal blood perfusion depending on the stage of development. In this study, we aimed to investigate the effec
Externí odkaz:
https://doaj.org/article/bca08208558c4bd4873129488493152b
Autor:
Olivia Nonn, Lilli Bonstingl, Katja Sallinger, Lena Neuper, Julia Fuchs, Martin Gauster, Berthold Huppertz, Dagmar Brislinger, Amin El-Heliebi, Herbert Fluhr, Eva Kampelmühler, Philipp Klaritsch
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Pregnant women have an increased risk of getting infected with SARS-CoV-2 and are more prone to severe illness. Data on foetal demise in affected pregnancies and its underlying aetiology is scarce and pathomechanisms remain largel
Externí odkaz:
https://doaj.org/article/99e6721d49e04522aa7576d12a5112a6
Autor:
Désirée Forstner, Jacqueline Guettler, Beatrice A. Brugger, Freya Lyssy, Lena Neuper, Christine Daxboeck, Gerhard Cvirn, Julia Fuchs, Kristin Kraeker, Alina Frolova, Daniela S. Valdes, Christina Stern, Birgit Hirschmugl, Herbert Fluhr, Christian Wadsack, Berthold Huppertz, Olivia Nonn, Florian Herse, Martin Gauster
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Tissue insults in response to inflammation, hypoxia and ischemia are accompanied by the release of ATP into the extracellular space. There, ATP modulates several pathological processes, including chemotaxis, inflammasome induction and platelet activa
Externí odkaz:
https://doaj.org/article/a66dbffd2a5348b3ace6efb87477d991
Autor:
Lena Neuper, Daniel Kummer, Désirée Forstner, Jacqueline Guettler, Nassim Ghaffari-Tabrizi-Wizsy, Cornelius Fischer, Herbert Juch, Olivia Nonn, Martin Gauster
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12326 (2022)
Angiotensin II receptor 1 blockers are commonly used to treat hypertension in women of childbearing age. While the fetotoxic effects of these drugs in the second and third trimesters of pregnancy are well documented, their possible impacts on placent
Externí odkaz:
https://doaj.org/article/66f4dbf553af4fbba226ad55b5892dc3
Autor:
Jelena Krstic, Alexander Deutsch, Julia Fuchs, Martin Gauster, Tina Gorsek Sparovec, Ursula Hiden, Julian Christopher Krappinger, Gerit Moser, Katrin Pansy, Marta Szmyra, Daniela Gold, Julia Feichtinger, Berthold Huppertz
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1065 (2022)
Placenta-specific trophoblast and tumor cells exhibit many common characteristics. Trophoblast cells invade maternal tissues while being tolerated by the maternal immune system. Similarly, tumor cells can invade surrounding tissues and escape the imm
Externí odkaz:
https://doaj.org/article/c2aeccb92ac64f8d888bc4fef60274b5
Autor:
Christina Stern, Sarah Schwarz, Gerit Moser, Silvija Cvitic, Evelyn Jantscher-Krenn, Martin Gauster, Ursula Hiden
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12722 (2021)
The placenta is an endocrine fetal organ, which secretes a plethora of steroid- and proteo-hormones, metabolic proteins, growth factors, and cytokines in order to adapt maternal physiology to pregnancy. Central to the growth of the fetus is the suppl
Externí odkaz:
https://doaj.org/article/6042246efa6b400eb37ef0fe28ed670e
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10732 (2021)
Upon activation, maternal platelets provide a source of proinflammatory mediators in the intervillous space of the placenta. Therefore, platelet-derived factors may interfere with different trophoblast subtypes of the developing human placenta and mi
Externí odkaz:
https://doaj.org/article/0cb229ec190e4fe2ada29cb020627a87
Autor:
Alejandro Majali-Martinez, Ursula Weiss-Fuchs, Heidi Miedl, Desiree Forstner, Julia Bandres-Meriz, Denise Hoch, Josip Djelmis, Marina Ivanisevic, Ursula Hiden, Martin Gauster, Gernot Desoye
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 10989 (2021)
Type 1 diabetes mellitus (T1DM) is associated with reduced fetal growth in early pregnancy, but a contributing role of the placenta has remained elusive. Thus, we investigated whether T1DM alters placental development in the first trimester. Using a
Externí odkaz:
https://doaj.org/article/8040b46ed4ee4a93b7930bf843631aa9
Autor:
Katharina B. Kuentzel, Ivan Bradić, Alena Akhmetshina, Melanie Korbelius, Silvia Rainer, Dagmar Kolb, Martin Gauster, Nemanja Vujić, Dagmar Kratky
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10416 (2021)
Cholesterol and fatty acids are essential lipids that are critical for membrane biosynthesis and fetal organ development. Cholesteryl esters (CE) are degraded by hormone-sensitive lipase (HSL) in the cytosol and by lysosomal acid lipase (LAL) in the
Externí odkaz:
https://doaj.org/article/cf81f782e3b44dc7abe7bfa201f7c13d
Autor:
Sarah M. Kedziora, Kristin Kräker, Lajos Markó, Julia Binder, Meryam Sugulle, Martin Gauster, Dominik N. Müller, Ralf Dechend, Nadine Haase, Florian Herse
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3762 (2021)
Preeclampsia (PE) is characterized by the onset of hypertension (≥140/90 mmHg) and presence of proteinuria (>300 mg/L/24 h urine) or other maternal organ dysfunctions. During human PE, renal injuries have been observed. Some studies suggest that wo
Externí odkaz:
https://doaj.org/article/3c5603cffa53406baa9693b3424ca8d5