Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Martin Garrido‐Rodriguez"'
Autor:
Mira L Burtscher, Stephan Gade, Martin Garrido-Rodriguez, Anna Rutkowska, Thilo Werner, H Christian Eberl, Massimo Petretich, Natascha Knopf, Katharina Zirngibl, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff, Maria Fälth-Savitski, Julio Saez-Rodriguez
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 4, Pp 458-474 (2024)
Abstract Complex disease phenotypes often span multiple molecular processes. Functional characterization of these processes can shed light on disease mechanisms and drug effects. Thermal Proteome Profiling (TPP) is a mass-spectrometry (MS) based tech
Externí odkaz:
https://doaj.org/article/6a429efa9e5f4ec6975418af5d3be112
Autor:
Daniel Dimitrov, Dénes Türei, Martin Garrido-Rodriguez, Paul L. Burmedi, James S. Nagai, Charlotte Boys, Ricardo O. Ramirez Flores, Hyojin Kim, Bence Szalai, Ivan G. Costa, Alberto Valdeolivas, Aurélien Dugourd, Julio Saez-Rodriguez
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Multiple methods to infer cell-cell communication (CCC) from single cell data are currently available. Here, the authors systematically compare 16 CCC inference resources and 7 methods, and develop the LIANA framework as an interface to use and compa
Externí odkaz:
https://doaj.org/article/4d3fd7c242584bd58262aeacf19fb079
Autor:
Martin Garrido‐Rodriguez, Katharina Zirngibl, Olga Ivanova, Sebastian Lobentanzer, Julio Saez‐Rodriguez
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 7, Pp n/a-n/a (2022)
Abstract Signal transduction governs cellular behavior, and its dysregulation often leads to human disease. To understand this process, we can use network models based on prior knowledge, where nodes represent biomolecules, usually proteins, and edge
Externí odkaz:
https://doaj.org/article/2407e044686f4858bdba6c6dc45f7460
Autor:
Oliver Hartmann, Michaela Reissland, Carina R. Maier, Thomas Fischer, Cristian Prieto-Garcia, Apoorva Baluapuri, Jessica Schwarz, Werner Schmitz, Martin Garrido-Rodriguez, Nikolett Pahor, Clare C. Davies, Florian Bassermann, Amir Orian, Elmar Wolf, Almut Schulze, Marco A. Calzado, Mathias T. Rosenfeldt, Markus E. Diefenbacher
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Lung cancer is the most common cancer worldwide and the leading cause of cancer-related deaths in both men and women. Despite the development of novel therapeutic interventions, the 5-year survival rate for non-small cell lung cancer (NSCLC) patients
Externí odkaz:
https://doaj.org/article/25bb6c9a9e3b4539a37791d85b52657e
Autor:
Oliver, Hartmann, Michaela, Reissland, Carina R, Maier, Thomas, Fischer, Cristian, Prieto-Garcia, Apoorva, Baluapuri, Jessica, Schwarz, Werner, Schmitz, Martin, Garrido-Rodriguez, Nikolett, Pahor, Clare C, Davies, Florian, Bassermann, Amir, Orian, Elmar, Wolf, Almut, Schulze, Marco A, Calzado, Mathias T, Rosenfeldt, Markus E, Diefenbacher
Publikováno v:
Frontiers in Cell and Developmental Biology
Lung cancer is the most common cancer worldwide and the leading cause of cancer-related deaths in both men and women. Despite the development of novel therapeutic interventions, the 5-year survival rate for non-small cell lung cancer (NSCLC) patients
Autor:
Rafael Jiménez-Izquierdo, Rosario Morrugares, Lucía Suanes-Cobos, Alejandro Correa-Sáez, Martín Garrido-Rodríguez, Laura Cerero-Tejero, Omar M. Khan, Susana de la Luna, Rocío Sancho, Marco A. Calzado
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-14 (2023)
Abstract FBXW7 is a member of the F-box protein family, which functions as the substrate recognition component of the SCF E3 ubiquitin ligase. FBXW7 is a main tumor suppressor due to its ability to control proteasome-mediated degradation of several o
Externí odkaz:
https://doaj.org/article/9aee63207e8647eaa6ccbe6db4bdeada
Autor:
Adela García-Martín, Carmen Navarrete, Martin Garrido-Rodríguez, María E. Prados, Diego Caprioglio, Giovanni Appendino, Eduardo Muñoz
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 142, Iss , Pp 112007- (2021)
Some cannabinoids showed anti-inflammatory and antifibrotic activities. EHP-101 is an oral lipidic formulation of the novel non-psychotropic cannabidiol aminoquinone VCE-004.8, which showed antifibrotic activity in murine models of systemic sclerosis
Externí odkaz:
https://doaj.org/article/25da05495a90450eb804e5c2de2fb622
Autor:
Martín Garrido-Rodriguez, Daniel Lopez-Lopez, Francisco M Ortuno, María Peña-Chilet, Eduardo Muñoz, Marco A Calzado, Joaquin Dopazo
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008748 (2021)
MIGNON is a workflow for the analysis of RNA-Seq experiments, which not only efficiently manages the estimation of gene expression levels from raw sequencing reads, but also calls genomic variants present in the transcripts analyzed. Moreover, this i
Externí odkaz:
https://doaj.org/article/65ddef7a579444e2b145e6b95460fc76
Autor:
Carmen Navarrete, Adela García-Martin, Martín Garrido-Rodríguez, Leyre Mestre, Ana Feliú, Carmen Guaza, Marco A. Calzado, Eduardo Muñoz
Publikováno v:
Neurobiology of Disease, Vol 143, Iss , Pp 104994- (2020)
Multiple Sclerosis (MS) is characterized by a combination of inflammatory and neurodegenerative processes in the spinal cord and the brain. Natural and synthetic cannabinoids such as VCE-004.8 have been studied in preclinical models of MS and represe
Externí odkaz:
https://doaj.org/article/2b42990554544d50a9bff731ebb14b53
Autor:
Laura Casares, Víctor García, Martín Garrido-Rodríguez, Estrella Millán, Juan A. Collado, Adela García-Martín, Jon Peñarando, Marco A. Calzado, Laureano de la Vega, Eduardo Muñoz
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Cannabidiol (CBD) is a major non-psychotropic phytocannabinoid that attracted a great attention for its therapeutic potential against different pathologies including skin diseases. However, although the efficacy in preclinical models and the clinical
Externí odkaz:
https://doaj.org/article/f5b8c7b912af43548f7298e90e944b3f