Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Martin G. de Vries"'
Autor:
Jan Paul van Loon, Martin G. de Vries, Thomas I. F. H. Cremers, Marieke C. G. van der Hart, Ben H.C. Westerink, Bjarke Ebert, Kirsten D. Huinink, Elizabeth C. M. de Lange
Publikováno v:
Journal of Neuroscience Methods, 178(2), 249-254. ELSEVIER SCIENCE BV
The only method to quantify free extracellular levels of drugs in the brain of living animals is microdialysis. However, quantitative microdialysis has been hampered by methodological issues for decades. The problems arise from the need to establish
Autor:
I. Martins, Ben H. C. Westerink, Martin G. de Vries, Steven P. Wilson, Isaura Tavares, Armando Teixeira-Pinto, Paulina Carvalho
Publikováno v:
Anesthesiology. 123(3)
Background: Noradrenaline reuptake inhibitors are known to produce analgesia through a spinal action but they also act in the brain. However, the action of noradrenaline on supraspinal pain control regions is understudied. The authors addressed the n
Autor:
Ben H.C. Westerink, Isaura Tavares, Paulina Carvalho, I. Martins, Armando Teixeira-Pinto, Martin G. de Vries, Steven P. Wilson
Publikováno v:
Pain. 156(8)
The dorsal reticular nucleus (DRt) plays a key role in facilitation of nociceptive transmission at the spinal cord. In this study, we evaluated the mechanisms involved in GABA-mediated control of the DRt focusing on the role of local GABAB receptors.
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 289:R977-R981
During insulin-induced hypoglycemia, there is an increase in extracellular norepinephrine (NE) in the ventromedial hypothalamus (VMH). This brain area is known to play an important role in integrated hormonal and behavioral responses to systemic hypo
Publikováno v:
Analytical Chemistry, 85(22), 10949-10955. AMER CHEMICAL SOC INC
Continuous glucose monitoring (CGM) is an important aid for diabetic patients to optimize glycemic control and to prevent long-term complications. However, current CGM devices need further miniaturization and improved functional performance. We have
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 286(5)
This study evaluated whether attenuation of sympathoadrenal responses to recurrent hypoglycemia is mediated by diminished noradrenergic activity in the hypothalamus. Male Sprague-Dawley rats received either once daily insulin (1.0 units/kg) injection
Publikováno v:
Diabetes. 52(11)
The activity of neurons in the ventromedial hypothalamus (VMH) important for initiating compensatory responses to hypoglycemia is influenced by ambient glucose concentration. In the present study, we used in vivo microdialysis to evaluate interstitia