Zobrazeno 1 - 10
of 712
pro vyhledávání: '"Martin G. Larson"'
Autor:
Patricia E. Miller, Priya Gajjar, Gary F. Mitchell, Sadiya S. Khan, Ramachandran S. Vasan, Martin G. Larson, Gregory D. Lewis, Ravi V. Shah, Matthew Nayor
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 3279-3289 (2024)
Abstract Aims New tools are needed to identify heart failure (HF) risk earlier in its course. We evaluated the association of multidimensional cardiopulmonary exercise testing (CPET) phenotypes with subclinical risk markers and predicted long‐term
Externí odkaz:
https://doaj.org/article/27d9174b544d4deca982e05568f0ef56
Autor:
Tianxiao Huan, Roby Joehanes, Jian Rong, Ming-Huei Chen, Rima Mustafa, Abbas Dehghan, Mohsen Ghanbari, Hannah Karlin, Shih-Jen Hwang, Paul Courchesne, Martin G. Larson, Andrew D. Johnson, Jane E. Freedman, Daniel Levy
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110988- (2024)
Summary: MicroRNAs, crucial in regulating protein-coding gene expression, are implicated in various diseases. We performed a genome-wide association study of plasma miRNAs (ex-miRNAs) in 3,743 Framingham Heart Study (FHS) participants and identified
Externí odkaz:
https://doaj.org/article/0af562d70c8345678e66f7cd70367565
Autor:
Sandhiya Ravichandran, Priya Gajjar, Maura E. Walker, Brenton Prescott, Connie W. Tsao, Mawra Jha, Prashant Rao, Patricia Miller, Martin G. Larson, Ramachandran S. Vasan, Ravi V. Shah, Vanessa Xanthakis, Gregory D. Lewis, Matthew Nayor
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background The relation of cardiorespiratory fitness (CRF) to lifestyle behaviors and factors linked with cardiovascular health remains unclear. We aimed to understand how the American Heart Association's Life's Essential 8 (LE8) score (and its chang
Externí odkaz:
https://doaj.org/article/a8330f7ca0a44f87a7f4dc1a2b839653
Autor:
Rebecca J. Song, Martin G. Larson, Hugo J. Aparicio, J. Michael Gaziano, Peter Wilson, Kelly Cho, Ramachandran S. Vasan, Matthew P. Fox, Luc Djoussé, On Behalf Of the Million Veteran Program
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background There is inconsistent evidence on the association of moderate alcohol consumption and stroke risk in the general population and is not well studied among U.S. Veterans. Furthermore, it is unclear whether primarily drinking beer, w
Externí odkaz:
https://doaj.org/article/041e15c4536e4261b60d9509ea8afa7a
Autor:
Elena V. Feofanova, Michael R. Brown, Taryn Alkis, Astrid M. Manuel, Xihao Li, Usman A. Tahir, Zilin Li, Kevin M. Mendez, Rachel S. Kelly, Qibin Qi, Han Chen, Martin G. Larson, Rozenn N. Lemaitre, Alanna C. Morrison, Charles Grieser, Kari E. Wong, Robert E. Gerszten, Zhongming Zhao, Jessica Lasky-Su, NHLBI Trans-Omics for Precision Medicine (TOPMed), Bing Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Circulating metabolite levels may reflect the state of the human organism in health and disease, however, the genetic architecture of metabolites is not fully understood. We have performed a whole-genome sequencing association analysis of bo
Externí odkaz:
https://doaj.org/article/fd8c3eb176234d4c8fc8bb86a09934a5
Autor:
Matthew Nayor, Priya Gajjar, Patricia Miller, Venkatesh L. Murthy, Ravi V. Shah, Nicholas E. Houstis, Raghava S. Velagaleti, Martin G. Larson, Ramachandran S. Vasan, Gregory D. Lewis, Gary F. Mitchell
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background During exercise, a healthy arterial system facilitates increased blood flow and distributes it effectively to essential organs. Accordingly, we sought to understand how arterial stiffening might impair cardiorespiratory fitness in communit
Externí odkaz:
https://doaj.org/article/39cae384aa64483187b7d78039fb5ffc
Autor:
Honghuang Lin, Alan C. Kwan, Cecilia Castro-Diehl, Meghan I. Short, Vanessa Xanthakis, Ibrahim M. Yola, Gerran Salto, Gary F. Mitchell, Martin G. Larson, Ramachandran S. Vasan, Susan Cheng
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract The drivers of sexual dimorphism in heart failure phenotypes are currently poorly understood. Divergent phenotypes may result from differences in heritability and genetic versus environmental influences on the interplay of cardiac structure
Externí odkaz:
https://doaj.org/article/69d134e7d644458c851acfb610f53b02
Autor:
Jasper Tromp, David Bauer, Brian L. Claggett, Matthew Frost, Mathias Bøtcher Iversen, Narayana Prasad, Mark C. Petrie, Martin G. Larson, Justin A. Ezekowitz, Scott D. Solomon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Deep learning can automate the interpretation of medical imaging tests. Here, the authors formally assess the interchangeability of deep learning algorithms with expert human measurements for interpreting echocardiographic studies.
Externí odkaz:
https://doaj.org/article/399be6a8039f45d19de79a68ec302dd6
Autor:
Daniel Gonzalez Izundegui, Patricia E. Miller, Ravi V. Shah, Clary B. Clish, Maura E. Walker, Gary F. Mitchell, Robert E. Gerszten, Martin G. Larson, Ramachandran S. Vasan, Matthew Nayor
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background New biomarkers to identify cardiovascular disease (CVD) risk earlier in its course are needed to enable targeted approaches for primordial prevention. We evaluated whether intraindividual changes in blood metabolites in response t
Externí odkaz:
https://doaj.org/article/fa2a77f62fbc47a9958baa44aa8a585e
Autor:
Yi Li, Ayana Gray, Liying Xue, Melissa G. Farb, Nir Ayalon, Charlotte Andersson, Darae Ko, Emelia J. Benjamin, Daniel Levy, Ramachandran S. Vasan, Martin G. Larson, Jian Rong, Vanessa Xanthakis, Chunyu Liu, Jessica L. Fetterman, Deepa M. Gopal
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)
Background The American Heart Association's framework “ideal cardiovascular health” (CVH) focuses on modifiable risk factors to reduce cardiovascular disease (CVD). Metabolomics provides important pathobiological insights into risk factors and CV
Externí odkaz:
https://doaj.org/article/d355e82bff914ecd806f016c4a0ef577