Validation of whole-slide digitally imaged melanocytic lesions: Does z-stack scanning improve diagnostic accuracy?

Autor: Bart Sturm, David Creytens, Martin G Cook, Jan Smits, Marcory C. R. F. van Dijk, Erik Eijken, Eline Kurpershoek, Heidi V. N Küsters-Vandevelde, Ariadne H. A. G. Ooms, Carla Wauters, Willeke A. M. Blokx, Jeroen A. W. M. van der Laak

Publikováno v: Journal of Pathology Informatics, Vol 10, Iss 1, Pp 6-6 (2019)

Background: Accurate diagnosis of melanocytic lesions is challenging, even for expert pathologists. Nowadays, whole-slide imaging (WSI) is used for routine clinical pathology diagnosis in several laboratories. One of the limitations of WSI, as it is

Externí odkaz: https://doaj.org/article/a97fb7ed54fd4943b24677232d1e903a

Impact of second opinion pathology review in the diagnosis and management of atypical melanocytic lesions: A prospective study of the Italian Melanoma Intergroup (IMI) and EORTC Melanoma Group

Autor: Daniela Massi, Anna Szumera-Ciećkiewicz, Lucia Alos, Sara Simi, Filippo Ugolini, Giuseppe Palmieri, Ignazio Stanganelli, Martin G. Cook, Mario Mandalà

Publikováno v: European Journal of Cancer.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2ec88c4d4f6d76b3e2aef263e1c4066
https://doi.org/10.1016/j.ejca.2023.05.009

Impact of Next-generation Sequencing on Interobserver Agreement and Diagnosis of Spitzoid Neoplasms

Autor: Lyn M. Duncan, Alexander J. Lazar, Artur Zembowicz, Christopher R. Shea, Raymond L. Barnhill, Pedram Gerami, Jane L. Messina, Birgitta Schmidt, Lorenzo Cerroni, Richard A. Scolyer, Martin G. Cook, Iwei Yeh, Daniela Mihic-Probst, Lori Lowe, Klaus J. Busam, Martin C. Mihm, Jeffrey Zhao, Sook Jung Yun, David E. Elder, Armita Bahrami, Daniela Massi, Sarah Benton, Victor A Tron, Michael W. Piepkorn, Arnaud de la Fouchardière, Xiaowei Xu, Michael T. Tetzlaff, Bin Zhang, Gilles Landman, Iva Johansson, Philip E. LeBoit

Publikováno v: American Journal of Surgical Pathology. 45:1597-1605

Atypical Spitzoid melanocytic tumors are diagnostically challenging. Many studies have suggested various genomic markers to improve classification and prognostication. We aimed to assess whether next-generation sequencing studies using the Tempus xO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f230169f993c4ea7f6a06c64b5673eb
https://doi.org/10.1097/pas.0000000000001753

Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma

Autor: Paul Lorigan, Rohit Thakur, Miles C. Andrews, Kate Hogan, Piyushkumar A. Mundra, Richard Marais, Martin G. Cook, Kang Zeng, Louis Boon, Antonia Banyard, Nathalie Dhomen, Matthew Smith, Jennifer A. Wargo, Jonathan Greenall, Elena Galvani, Garry Ashton, A. Mandal, Beth A. Helmink, Pablo Garcia-Martinez, Gabriela Gremel, Christopher P. E. Chester, Sara Valpione

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Galvani, E, Mundra, P A, Valpione, S, Garcia-Martinez, P, Smith, M, Greenall, J, Thakur, R, Helmink, B, Andrews, M C, Boon, L, Chester, C, Gremel, G, Hogan, K, Mandal, A, Zeng, K, Banyard, A, Ashton, G, Cook, M, Lorigan, P, Wargo, J A, Dhomen, N & Marais, R 2020, ' Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma ', Nature Communications, vol. 11, no. 1, pp. 853 . https://doi.org/10.1038/s41467-020-14632-2
Nature Communications

Although immune checkpoint inhibitors (ICIs) have achieved unprecedented results in melanoma, the biological features of the durable responses initiated by these drugs remain unknown. Here we show the genetic and phenotypic changes induced by treatme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556e5bce3c32f9fe3828bc8a54567eaf
http://link.springer.com/article/10.1038/s41467-020-14632-2

Current role of sentinel lymph node biopsy in the management of cutaneous melanoma: A UK consensus statement

Autor: Pippa Corrie, B Powell, P King, R Pritchard-Jones, Ruth E Board, Martin G. Cook, Mark R. Middleton, Paul Nathan, Sally Ellis, J.M.G. Larkin, J Marsden, Marc Moncrieff, Neil Steven, Howard Peach, Paul Lorigan, Jenny L. C. Geh, Simon Rodwell, G Laitung

Publikováno v: Journal of Plastic, Reconstructive & Aesthetic Surgery. 73:36-42

Summary Sentinel node biopsy (SNB) has been at the forefront of the surgical staging of melanoma patients for the past 15 years. The high accuracy of this prognostic staging procedure is now recognised in all international guidelines for melanoma. Ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbf1bba2bdc8195ba47de41ab66e1ce
https://doi.org/10.1016/j.bjps.2019.06.020