Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Martin Filipec"'
Autor:
Andrea Stadnikova, Lubica Dudakova, Pavlina Skalicka, Zdenek Valenta, Martin Filipec, Katerina Jirsova
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175509 (2017)
Posterior polymorphous corneal dystrophy (PPCD) is characterized by abnormal proliferation of corneal endothelial cells. It was shown that TGF-β2 present in aqueous humor (AH) could help maintaining the corneal endothelium in a G1-phase-arrest state
Externí odkaz:
https://doaj.org/article/da1e8d80b7cc418091b6ab4af2582ef3
Autor:
Petra Liskova, Rhian Gwilliam, Martin Filipec, Katerina Jirsova, Stanislava Reinstein Merjava, Panos Deloukas, Tom R Webb, Shomi S Bhattacharya, Neil D Ebenezer, Alex G Morris, Alison J Hardcastle
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45495 (2012)
Posterior polymorphous corneal dystrophy (PPCD) is a rare autosomal dominant genetically heterogeneous disorder. Nineteen Czech PPCD pedigrees with 113 affected family members were identified, and 17 of these kindreds were genotyped for markers on ch
Externí odkaz:
https://doaj.org/article/3db6f0fbd97f483eadb7b26a06a19a39
Autor:
James D. Lauderdale, Viera Vesela, Michalis Palos, Stanislava Merjava, Pavlina Skalicka, Lubica Dudakova, Gabriela Mahelkova, Sek-Shir Cheong, Enkela Hrdlickova, Deli Krizova, Jena L. Chojnowski, Martin Hlozanek, Katerina Jirsova, Martin Filipec, Marcela Michalickova, Petra Liskova, Marie Trkova, Alison J. Hardcastle, Vincent Plagnol, Nikolas Pontikos
Publikováno v:
Stem cell reviews and reports. 14(1)
Autor:
Stephen J. Tuft, Petra Liskova, Pavlina Hrabcikova, Katerina Jirsova, Cerys J. Evans, Lubica Dudakova, Alice E. Davidson, Ales Horinek, Alison J. Hardcastle, Martin Filipec
Publikováno v:
Annals of Human Genetics. 79:1-9
Summary Posterior polymorphous corneal dystrophy 3 (PPCD3) is a rare autosomal dominant disorder caused by mutations in ZEB1. To date all identified disease-causing variants were unique to the studied families, except for c.1576dup. We have detected
Autor:
Aref Al Fakih, Martin Filipec, Ivana Krabcova, Kristyna Brejchova, Katerina Jirsova, Viera Vesela, Michalis Palos
Publikováno v:
Current Eye Research. 39:21-30
To assess the impact of autologous serum (AS) eye drops on the ocular surface of patients with bilateral severe dry eye and to draw a comparison between the clinical and laboratory examinations and the degree of subjective symptoms before and after s
Autor:
Eva Malinova, Stanislava Merjava, Zuzana Zemanova, Katerina Jirsova, Kyra Michalova, Petra Liskova, Martin Filipec
Publikováno v:
Histochemistry and Cell Biology. 136:93-101
Posterior polymorphous corneal dystrophy (PPCD) is a rare, bilateral autosomal dominant disorder affecting primarily the corneal endothelium and descemet membrane (DM). The aim of this study was to establish the origin of abnormal endothelium in a pa
Publikováno v:
Transplant Immunology. 24:189-194
Limbal transplantation or limbal stem cell (LSC) transfer represents the only way to treat severe ocular surface damage or LSC deficiency. However, limbal allografts are promptly rejected in spite of extensive immunosuppressive therapy. To characteri
Publikováno v:
European Journal of Haematology. 63:1-10
We have studied the expression of cytokine receptors CD25 (IL-2R alpha, 55 kD), CD116 (hGM-CSFR, 145 kD), CD117 (CSFR, 145 kD), CD120a (TNFR, 55 kD), CD120b (TNFR, 75 kD), CD121a (IL-1R, type I, 80 kD), CDw123 (IL-3R), CD124 (IL-4R, 140 kD), CD126 (I
Autor:
Gordon K. Klintworth, Brandy L. Bowling, Martin Filipec, Shomi S. Bhattacharya, Katerina Jirsova, Stephen J. Tuft, Petra Liskova, Neil D. Ebenezer, Alison J. Hardcastle
Publikováno v:
Ophthalmic Research. 40:105-108
Aims: To evaluate mutations in the transforming-growth-factor-β-induced (TGFBI) gene in patients of Czech origin with autosomal dominant corneal dystrophies. Methods: The coding sequence of the TGFBI gene was analysed in 22 affected Czech individual
Autor:
Martin Filipec, Klara Sedlakova
Publikováno v:
Cornea. 26:1111-1114
PURPOSE Understanding xenograft rejection is crucial for the potential introduction of xenotransplantation into clinical practice. Small-animal models play an essential role in this context and substantially contribute to our knowledge about mechanis