Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Martin Fernandez-Zapico"'
Publikováno v:
F1000Research, Vol 3 (2014)
Aberrant activation of the transcription factor GLI1, a central effector of the Hedgehog (HH) pathway, is associated with several malignancies, including pancreatic ductal adenocarcinoma (PDAC), one of most deadly human cancers. GLI1 has been describ
Externí odkaz:
https://doaj.org/article/3bb4a98c878c4ac9928117ff93ce2641
Autor:
Angela Mathison, Adrienne Grzenda, Gwen Lomberk, Gabriel Velez, Navtej Buttar, Pamela Tietz, Helen Hendrickson, Ann Liebl, Yuning Y Xiong, Gregory Gores, Martin Fernandez-Zapico, Nicholas F Larusso, William Faubion, Vijay H Shah, Raul Urrutia
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75311 (2013)
Krüppel-like factor 11 (KLF11) and the highly homologous KLF10 proteins are transcription factors originating from duplication of the Drosophila melanogaster ancestor cabut. The function of these proteins in epithelial cells has been previously char
Externí odkaz:
https://doaj.org/article/282c282af9ac4f8c896a9236ce0e4841
Autor:
Yujia Bian, Diego Alem, Francisca Beato, Tara L. Hogenson, Xinrui Yang, Kun Jiang, Jianfeng Cai, Wen Wee Ma, Martin Fernandez-Zapico, Aik Choon Tan, Nicholas J. Lawrence, Jason B. Fleming, Yu Yuan, Hao Xie
Publikováno v:
Journal of Medicinal Chemistry. 65:16432-16450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f98bc66cedf074cb006a531581df423e
https://doi.org/10.1021/acs.jmedchem.2c01300
https://doi.org/10.1021/acs.jmedchem.2c01300
Parallel functional annotation of cancer-associated missense mutations in histone methyltransferases
Using exome sequencing for biomarker discovery and precision medicine requires connecting nucleotide-level variation with functional changes in encoded proteins. However, for functionally annotating the thousands of cancer-associated missense mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43823ba06bc0f967b8b03ddd991ea68a
https://doi.org/10.21203/rs.3.rs-1746399/v1
https://doi.org/10.21203/rs.3.rs-1746399/v1
Autor:
Madeline Ross, Renzo Vera, Maite Fernandez-Barrena, Murat Toruner, Ezequiel Tolosa, Luciana Almada, Rolf Brekken, Martin Fernandez-Zapico
Publikováno v:
Innovation in Aging. 6:785-785
Pancreatic ductal adenocarcinoma (PDAC) affects many older adults in the United States. This aggressive type of pancreatic cancer is resistant to many chemotherapies, resulting in a poor prognosis and a five-year survival rate of less than ten percen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::844c8f4355ee7eb06ac2e66bccf861da
https://doi.org/10.1093/geroni/igac059.2837
https://doi.org/10.1093/geroni/igac059.2837
Autor:
Giacomo, Coltro, Abhishek A, Mangaonkar, Terra L, Lasho, Christy M, Finke, Prateek, Pophali, Ryan, Carr, Naseema, Gangat, Moritz, Binder, Animesh, Pardanani, Martin, Fernandez-Zapico, Keith D, Robertson, Alberto, Bosi, Nathalie, Droin, Alessandro M, Vannucchi, Ayalew, Tefferi, Anthony, Hunter, Eric, Padron, Eric, Solary, Mrinal M, Patnaik
Publikováno v:
Leukemia. 34(5)
Loss-of-function TET2 mutations (TET2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb4a4461495594eb113078cfc18fc718
https://pubmed.ncbi.nlm.nih.gov/31836856
https://pubmed.ncbi.nlm.nih.gov/31836856
Autor:
Barroso, Kim
Publikováno v:
Human health and pathology. Université de Bordeaux, 2016. English. ⟨NNT : 2016BORD0209⟩
P97/VCP is a member of the AAA+ ATPase family that plays major roles in various cellular processes including control of protein homeostasis and chromatin-associated functions (transcription, replication, DNA damage, cellular cycle progression). Moreo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c12feeb8bbacbde0dd90c3f7fe92fc6c
https://tel.archives-ouvertes.fr/tel-01968034/document
https://tel.archives-ouvertes.fr/tel-01968034/document
Autor:
Barroso, Kim
Publikováno v:
Human health and pathology. Université de Bordeaux, 2016. English. ⟨NNT : 2016BORD0209⟩
P97/VCP is a member of the AAA+ ATPase family that plays major roles in various cellular processes including control of protein homeostasis and chromatin-associated functions (transcription, replication, DNA damage, cellular cycle progression). Moreo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a79b39465842b3a0252d942dd9ca9805
http://hdl.handle.net/20.500.12278/5502
http://hdl.handle.net/20.500.12278/5502