Výsledky vyhledávání - "Martin FM de Rooij"

Possible Mechanisms Of Resistance To The Novel BH3-Mimetic ABT-199 In In Vitro Lymph Node Models Of CLL – The Role Of Abl and Btk

Autor: Rachel Thijssen, Christian R Geest, Martin FM de Rooij, Nora Liu, Bogdan I Florea, Katinka Weller, Hermen S Overkleeft, Marinus H.J. Van Oers, Marcel Spaargaren, Arnon P. Kater, Eric Eldering

Publikováno v: Blood. 122:4188-4188

The new BH3-mimetic ABT-199 antagonizes Bcl-2 and avoids the thrombocytopenia associated with clinical application of its predecessor ABT-263 (navitoclax). Chronic lymphocytic leukemia (CLL) cells are highly sensitive to ABT-199 and the first clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d00888ecbb102f61c76d41a258f87f1
https://doi.org/10.1182/blood.v122.21.4188.4188

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