Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Martin F. Bach"'
Publikováno v:
Rheumato, Vol 4, Iss 2, Pp 63-74 (2024)
This work aimed to investigate a potential link between serum IL-1β levels in patients with giant cell arteritis (GCA) and their responsiveness to combined anti-IL-6 receptor (IL-6R) and glucocorticoid (GC) treatments within the context of two separ
Externí odkaz:
https://doaj.org/article/96feca8c25c444dab048f6503a88b95e
Autor:
Romano Josi, Daniel E. Speiser, Simone de Brot, Anne-Cathrine Vogt, Eva M. Sevick-Muraca, Genrich V. Tolstonog, Martin F. Bachmann, Mona O. Mohsen
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109439- (2024)
Summary: The global incidence of human papillomavirus (HPV) associated head and neck carcinoma is on the rise, in response to this a tetravalent therapeutic vaccine named Qβ-HPVag was developed. This vaccine, utilizing virus-like particles (VLPs) lo
Externí odkaz:
https://doaj.org/article/a49fdf0e3fd7450d86b3b6168590695c
Autor:
Jan M. Sobczak, Irena Barkovska, Ina Balke, Dominik A. Rothen, Mona O. Mohsen, Dace Skrastina, Anete Ogrina, Byron Martina, Juris Jansons, Janis Bogans, Monique Vogel, Martin F. Bachmann, Andris Zeltins
Publikováno v:
Vaccines, Vol 12, Iss 6, p 661 (2024)
T help (Th), stimulation of toll-like receptors (pathogen-associated molecular patterns, PAMPs), and antigen organization and repetitiveness (pathogen-associated structural patterns, PASPs) were shown numerous times to be important in driving B-cell
Externí odkaz:
https://doaj.org/article/dd21e3c1a8eb4f19965421a98dc62725
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
The rising global incidence of IgE-mediated allergic reactions poses a significant challenge to the quality of life of affected individuals and to healthcare systems, with current treatments being limited in effectiveness, safety, and disease-modifyi
Externí odkaz:
https://doaj.org/article/ba77a043962c47d3991436105c44b29e
Autor:
Queenie Fernandes, Varghese Philipose Inchakalody, Maysaloun Merhi, Sarra Mestiri, Nassiba Taib, Dina Moustafa Abo El-Ella, Takwa Bedhiafi, Afsheen Raza, Lobna Al-Zaidan, Mona O. Mohsen, Mariam Ali Yousuf Al-Nesf, Ali Ait Hssain, Hadi Mohamad Yassine, Martin F. Bachmann, Shahab Uddin, Said Dermime
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 524-540 (2022)
The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for change in the form of newer and more adaptive diagnostic methods for the detection of SARS-CoV-2 infections. On the other hand, developing rapid and sensitive diagno
Externí odkaz:
https://doaj.org/article/ee3ec5dd64c44c558549a2623b2047e9
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1852 (2023)
The mechanisms of action of allergen-specific immunotherapy (AIT) are often referred to as the induction of ‘tolerance’. However, immunological ‘tolerance’ is defined as an alteration in the function or composition of immune cells. For AIT, t
Externí odkaz:
https://doaj.org/article/34a02d90422a4f548eb545cbafca6142
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
It is well established that immunoglobulin E (IgE) plays a crucial role in atopy by binding to two types of Fcε receptors (FcεRI and FcεRII, also known as CD23). The cross-linking of FcεRI-bound IgE on effector cells, such as basophils and mast c
Externí odkaz:
https://doaj.org/article/34b18a2486e745669094c2603f3751f4
Autor:
Anete Ogrina, Ina Balke, Ieva Kalnciema, Dace Skrastina, Juris Jansons, Martin F. Bachmann, Andris Zeltins
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Virus-like particles (VLPs) are virus-derived artificial nanostructures that resemble a native virus-stimulating immune system through highly repetitive surface structures. Improved safety profiles, flexibility in vaccine construction, and the ease o
Externí odkaz:
https://doaj.org/article/f31428eeb5c1404bb725f2cbd812544c
Autor:
Xinyue Chang, Xuelan Liu, Byron Martina, Andris Zeltins, Gilles Augusto, Monique Vogel, Mona O. Mohsen, Daniel E. Speiser, Martin F. Bachmann
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSARS-CoV-2 has developed a number of Variants of Concern (VOC) with increased infectivity and/or reduced recognition by neutralizing antibodies specific for the receptor binding domain (RBD) of the spike protein. Extended studies of other
Externí odkaz:
https://doaj.org/article/8997e4d91f0b4854ad635de68eacdb46
IgE glycans promote anti-IgE IgG autoantibodies that facilitate IgE serum clearance via Fc Receptors
Autor:
Kevin Plattner, Zahra Gharailoo, Simon Zinkhan, Paul Engeroff, Martin F. Bachmann, Monique Vogel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundRecent studies have shown that IgE glycosylation significantly impacts the ability of IgE to bind to its high-affinity receptor FcεRI and exert effector functions. We have recently demonstrated that immunizing mice with IgE in a complex wi
Externí odkaz:
https://doaj.org/article/351c439fc890445c9fb93c55d9d3e8c8