Zobrazeno 1 - 10
of 461
pro vyhledávání: '"Martin F Bachmann"'
Autor:
Filippo Ferri, Silvia Ferro, Federico Porporato, Carolina Callegari, Chiara Guglielmetti, Maria Mazza, Marta Ferrero, Chiara Crinò, Enrico Gallo, Michele Drigo, Luigi Michele Coppola, Gabriele Gerardi, Tim Paul Schulte, Stefano Ricagno, Monique Vogel, Federico Storni, Martin F Bachmann, Anne-Cathrine Vogt, Serena Caminito, Giulia Mazzini, Francesca Lavatelli, Giovanni Palladini, Giampaolo Merlini, Eric Zini
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0281822 (2023)
Systemic AA-amyloidosis is a protein-misfolding disease characterized by fibril deposition of serum amyloid-A protein (SAA) in several organs in humans and many animal species. Fibril deposits originate from abnormally high serum levels of SAA during
Externí odkaz:
https://doaj.org/article/6be68cb997bf4772b783fa246068499f
Autor:
Martin F Bachmann, Daniel E Speiser, Mona O Mohsen, Matthew Heath, Matthias F Kramer, Thalia Carreno Velazquez, Alan Bullimore, Murray A Skinner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Introduction Intratumoral injections of novel therapeutics can activate tumor antigen-specific T cells for locoregional tumor control and may even induce durable systemic protection (against distant metastases) via recirculating T cells. Here we expl
Externí odkaz:
https://doaj.org/article/17789b83693d4c3cbf6bf8e1743d20ab
Autor:
Martin F Bachmann, Said Dermime, Daniel E Speiser, Monique Vogel, Georges Coukos, Varghese Philipose Inchakalody, Mona O Mohsen, Justine Michaux, HuiSong Pak, Brian J Stevenson, Simone de Brot, Michal Bassani-Sternberg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/214a03bc5acf409c9a81b744a3de7f23
Autor:
Marika Doucet, Aadil El-Turabi, Franziska Zabel, Benjamin H M Hunn, Nora Bengoa-Vergniory, Milena Cioroch, Mauricio Ramm, Amy M Smith, Ariane Cruz Gomes, Gustavo Cabral de Miranda, Richard Wade-Martins, Martin F Bachmann
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181844 (2017)
Parkinson's disease (PD) is a progressive and currently incurable neurological disorder characterised by the loss of midbrain dopaminergic neurons and the accumulation of aggregated alpha-synuclein (a-syn). Oligomeric a-syn is proposed to play a cent
Externí odkaz:
https://doaj.org/article/701777da3c1e44d9bea88cf6df7890b6
Publikováno v:
Rheumato, Vol 4, Iss 2, Pp 63-74 (2024)
This work aimed to investigate a potential link between serum IL-1β levels in patients with giant cell arteritis (GCA) and their responsiveness to combined anti-IL-6 receptor (IL-6R) and glucocorticoid (GC) treatments within the context of two separ
Externí odkaz:
https://doaj.org/article/96feca8c25c444dab048f6503a88b95e
Autor:
Gunther Spohn, Christian Schori, Iris Keller, Katja Sladko, Christina Sina, Reto Guler, Katrin Schwarz, Pål Johansen, Gary T Jennings, Martin F Bachmann
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Neutralization of the inflammatory cytokine interleukin-1β (IL-1β) is a promising new strategy to prevent the β-cell destruction, which leads to type 2 diabetes. Here, we describe the preclinical development of a therapeutic vaccine against IL-1β
Externí odkaz:
https://doaj.org/article/56bc39e0b1774043a0401a3455439423
Autor:
Andrea Jegerlehner, Franziska Zabel, Alice Langer, Klaus Dietmeier, Gary T Jennings, Philippe Saudan, Martin F Bachmann
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78947 (2013)
Although current influenza vaccines are effective in general, there is an urgent need for the development of new technologies to improve vaccine production timelines, capacities and immunogenicity. Herein, we describe the development of an influenza
Externí odkaz:
https://doaj.org/article/05b89968b1c54e01845ed41e6fb4279a
Autor:
David A G Skibinski, Brendon J Hanson, Yufang Lin, Veronika von Messling, Andrea Jegerlehner, Jason Boon Sern Tee, De Hoe Chye, Steven K K Wong, Amanda A P Ng, Hui Yin Lee, Bijin Au, Bernett T K Lee, Lucia Santoso, Michael Poidinger, Anna-Marie Fairhurst, Alex Matter, Martin F Bachmann, Philippe Saudan, John E Connolly
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76571 (2013)
Influenza pandemics can spread quickly and cost millions of lives; the 2009 H1N1 pandemic highlighted the shortfall in the current vaccine strategy and the need for an improved global response in terms of shortening the time required to manufacture t
Externí odkaz:
https://doaj.org/article/eaf2880dd96c4e2887318de13c807206
Autor:
Dominik A. Rothen, Sudip Kumar Dutta, Pascal S. Krenger, Alessandro Pardini, Anne-Cathrine S. Vogt, Romano Josi, Ilva Lieknina, Albert D. M. E. Osterhaus, Mona O. Mohsen, Monique Vogel, Byron Martina, Kaspars Tars, Martin F. Bachmann
Publikováno v:
Vaccines, Vol 12, Iss 9, p 1053 (2024)
Declared as a Public Health Emergency in 2016 by the World Health Organization (WHO), the Zika virus (ZIKV) continues to cause outbreaks that are linked to increased neurological complications. Transmitted mainly by Aedes mosquitoes, the virus is spr
Externí odkaz:
https://doaj.org/article/e1c2ded499f140b9b93ae46ea1c677dc
Autor:
Dominik A. Rothen, Sudip Kumar Dutta, Pascal S. Krenger, Anne-Cathrine S. Vogt, Ilva Lieknina, Jan M. Sobczak, Albert D. M. E. Osterhaus, Mona O. Mohsen, Monique Vogel, Byron Martina, Kaspars Tars, Martin F. Bachmann
Publikováno v:
Vaccines, Vol 12, Iss 8, p 874 (2024)
Over the past few decades, dengue fever has emerged as a significant global health threat, affecting tropical and moderate climate regions. Current vaccines have practical limitations, there is a strong need for safer, more effective options. This st
Externí odkaz:
https://doaj.org/article/830ee719f87c4fe5bc015019897b55cc