Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Martin F, Wolfson"'
Autor:
Mark F. Maurer, Katherine E. Lewis, Joseph L. Kuijper, Dan Ardourel, Chelsea J. Gudgeon, Siddarth Chandrasekaran, Sherri L. Mudri, Kayla N. Kleist, Chris Navas, Martin F. Wolfson, Mark W. Rixon, Ryan Swanson, Stacey R. Dillon, Steven D. Levin, Yengo Raymond Kimbung, Masato Akutsu, Derek T. Logan, Björn Walse, Kristine M. Swiderek, Stanford L. Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
CD28 costimulatory signalling can be suppressed by immune checkpoints, such as CTLA-4 and PD-1. Here the authors describe the design of the fusion therapeutic davoceticept (ALPN-202), based on a variant CD80 extracellular domain engineered to bind PD
Externí odkaz:
https://doaj.org/article/1c1e0e459c4147429eef80ef95841f04
Autor:
Steven D. Levin, Lawrence S. Evans, Susan Bort, Erika Rickel, Katherine E. Lewis, Rebecca P. Wu, Joseph Hoover, Sean MacNeil, David La, Martin F. Wolfson, Mark W. Rixon, Stacey R. Dillon, Michael G. Kornacker, Ryan Swanson, Stanford L. Peng
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Immunoglobulin superfamily member (IgSF) proteins play a significant role in regulating immune responses with surface expression on all immune cell subsets, making the IgSF an attractive family of proteins for therapeutic targeting in human diseases.
Externí odkaz:
https://doaj.org/article/bed901c0bf43422ba8dc0a6914b60717
Autor:
Stacey R. Dillon, Lawrence S. Evans, Katherine E. Lewis, Susan Debrot, Tiffany C. Blair, Sherri Mudri, Kayla Kleist, Steven D. Levin, Janhavi G. Bhandari, Logan Garrett, Martin F. Wolfson, Pamela M. Holland, Mark W. Rixon, Stanford L. Peng
Publikováno v:
Arthritis & Rheumatology.
Autor:
Lawrence S. Evans, Katherine E. Lewis, Daniel DeMonte, Janhavi G. Bhandari, Logan B. Garrett, Joseph L. Kuijper, Daniel Ardourel, Martin F. Wolfson, Susan Debrot, Sherri Mudri, Kayla Kleist, Luana L. Griffin, LuAnne Hebb, Russell J. Sanderson, NingXin Wang, Michelle Seaberg, Allison G. Chunyk, Jing Yang, Youji Hong, Zahra Maria, David J. Messenheimer, Pamela M. Holland, Stanford L. Peng, Mark W. Rixon, Stacey R. Dillon
Publikováno v:
Arthritis & Rheumatology.
Autor:
Stanford L. Peng, Martin F. Wolfson, Ryan Swanson, Steven D. Levin, LS Evans, Kristine M. Swiderek, E Rickel, Katherine E. Lewis, Stacey R. Dillon
Publikováno v:
Cancer Research. 79:P1-20
This abstract was withdrawn by the authors. Citation Format: Dillon SR, Evans LS, Rickel E, Lewis KE, Swanson R, Levin SD, Wolfson M, Peng SL, Swiderek KM. Withdrawn [abstract]. In: Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 De
Autor:
Jing Yang, Steven D. Levin, Bruce R. Blazar, Kushi Kushekhar, Djamilatou Adom, Rebecca Wu, Katherine E. Lewis, Ryan Swanson, Hao Liu, Samantha Hund, Kristine M. Swiderek, Keli L. Hippen, Amanda Albright, Sophie Paczesny, Maykala Kirksey, Jinfeng Yang, Sherri Mudri, Stanford L. Peng, Erika Rickel, Katherine Henderson, Abdulraouf Ramadan, Lawrence Evans, Titilayo Adeniyan, Stacey R. Dillon, Michelle A. Seaberg, Martin F. Wolfson, Chelsea J. Gudgeon
Publikováno v:
Science Translational Medicine. 12
Acute graft-versus-host disease (aGVHD) remains a major complication of allogeneic hematopoietic cell transplantation (HCT). CD146 and CCR5 are proteins that mark activated T helper 17 (Th17) cells. The Th17 cell phenotype is promoted by the interact
Autor:
Susan Bort, Katherine E. Lewis, Sean MacNeil, Stanford L. Peng, Mark W. Rixon, David La, Steven D. Levin, Erika Rickel, Ryan Swanson, Wu Rebecca, Lawrence Evans, Joseph Hoover, Martin F. Wolfson, Stacey R. Dillon, Michael Kornacker
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2020)
Frontiers in Immunology, Vol 10 (2020)
Immunoglobulin superfamily member (IgSF) proteins play a significant role in regulating immune responses with surface expression on all immune cell subsets, making the IgSF an attractive family of proteins for therapeutic targeting in human diseases.
Autor:
I Capuano, Michael Kornacker, S MacNeil, LS Evans, Stanford L. Peng, J Hoover, Martin F. Wolfson, SS Levin, M Rixon, E Rickel, Ryan Swanson, J Bhandari
Publikováno v:
Cancer Research. 78:P1-09
Background: The presence of tumor infiltrating lymphocytes (TILs) has been associated with improved prognosis in HER2+ breast cancer patients. Antigen specific TCR and costimulatory receptor signaling drive increases in TIL number, effector function,
Autor:
Siddarth Chandrasekaran, Demonte Daniel William, Logan Garrett, Stanford L. Peng, Ardourel Daniel F, Katherine E. Lewis, Sherri Mudri, Mark F. Maurer, Kayla N. Kleist, Michelle A. Seaberg, Jing Yang, Steven D. Levin, Mark W. Rixon, Joseph L. Kuijper, Rachel Wang, Stacey R. Dillon, Hieu Nguyen, Chelsea J. Gudgeon, Martin F. Wolfson
Publikováno v:
Cancer Research. 81:1740-1740
Introduction: Checkpoint inhibition (CPI) has been shown to be an effective anti-tumor therapy, but CPI alone is frequently insufficient to control tumor growth, and costimulatory signals may also be required to produce clinically significant anti-tu
Autor:
Djamilatou, Adom, Stacey R, Dillon, Jinfeng, Yang, Hao, Liu, Abdulraouf, Ramadan, Kushi, Kushekhar, Samantha, Hund, Amanda, Albright, Maykala, Kirksey, Titilayo, Adeniyan, Katherine E, Lewis, Lawrence, Evans, Rebecca, Wu, Steven D, Levin, Sherri, Mudri, Jing, Yang, Erika, Rickel, Michelle, Seaberg, Katherine, Henderson, Chelsea J, Gudgeon, Martin F, Wolfson, Ryan M, Swanson, Kristine M, Swiderek, Stanford L, Peng, Keli L, Hippen, Bruce R, Blazar, Sophie, Paczesny
Publikováno v:
Sci Transl Med
Acute graft-versus-host disease (aGVHD) remains a major complication of allogeneic hematopoietic cell transplantation (HCT). CD146 and CCR5 are proteins that mark activated T helper 17 (Th17) cells. The Th17 cell phenotype is promoted by the interact